Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India
IntroductionPrior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on dru...
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Published in | BMJ Public Health Vol. 2; no. 1; p. e000748 |
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Abstract | IntroductionPrior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on drug/vaccine development process.MethodsThis was an online survey conducted among young adults enrolled as students in a university in south India between 15 September 2022 and 31 October 2022. Until recently, these students attended online classes from various locations across India, likely reflecting a diverse regional and traditional background. Information regarding their sociodemographic status, awareness and perception about CR was collected and analysed applying the principle of descriptive and inferential statistics.ResultsA total of N=4796 eligible survey responses were analysed. Approximately, 50% were unfamiliar with CR but 42.4% expressed willingness to participate in a future CR. The significant predictors for a higher favourable perception score were having heard about CR (p<0.001), known exactly what a CR means (p<0.001) and having known anyone who participated in a CR (p<0.001). The significant predictors for willingness to participate in a CR were those living in villages as against those living in cities (p=0.002), belongs to Brahm Govind (BG) Prasad’s socioeconomic status class 1 (p=0.023) or class 4 (p=0.011) as against those in class 5, those who have heard about CR (p=0.023), participated in CR (p<0.001), have known someone participated in a CR (p<0.001) or higher total score of favourable perceptions (p<0.001).ConclusionsWhile there was extensive media coverage on drug/vaccine development processes during the COVID-19 pandemic, significant knowledge gaps and concerns regarding various aspects of CR persisted. Although some individuals showed a positive view of CR and its societal benefits, the overall public awareness remains insufficient. |
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AbstractList | Introduction Prior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on drug/vaccine development process.Methods This was an online survey conducted among young adults enrolled as students in a university in south India between 15 September 2022 and 31 October 2022. Until recently, these students attended online classes from various locations across India, likely reflecting a diverse regional and traditional background. Information regarding their sociodemographic status, awareness and perception about CR was collected and analysed applying the principle of descriptive and inferential statistics.Results A total of N=4796 eligible survey responses were analysed. Approximately, 50% were unfamiliar with CR but 42.4% expressed willingness to participate in a future CR. The significant predictors for a higher favourable perception score were having heard about CR (p<0.001), known exactly what a CR means (p<0.001) and having known anyone who participated in a CR (p<0.001). The significant predictors for willingness to participate in a CR were those living in villages as against those living in cities (p=0.002), belongs to Brahm Govind (BG) Prasad’s socioeconomic status class 1 (p=0.023) or class 4 (p=0.011) as against those in class 5, those who have heard about CR (p=0.023), participated in CR (p<0.001), have known someone participated in a CR (p<0.001) or higher total score of favourable perceptions (p<0.001).Conclusions While there was extensive media coverage on drug/vaccine development processes during the COVID-19 pandemic, significant knowledge gaps and concerns regarding various aspects of CR persisted. Although some individuals showed a positive view of CR and its societal benefits, the overall public awareness remains insufficient. IntroductionPrior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus, we aim to investigate if the pandemic has influenced awareness and attitudes towards CR given the wide mass and social media coverage on drug/vaccine development process.MethodsThis was an online survey conducted among young adults enrolled as students in a university in south India between 15 September 2022 and 31 October 2022. Until recently, these students attended online classes from various locations across India, likely reflecting a diverse regional and traditional background. Information regarding their sociodemographic status, awareness and perception about CR was collected and analysed applying the principle of descriptive and inferential statistics.ResultsA total of N=4796 eligible survey responses were analysed. Approximately, 50% were unfamiliar with CR but 42.4% expressed willingness to participate in a future CR. The significant predictors for a higher favourable perception score were having heard about CR (p<0.001), known exactly what a CR means (p<0.001) and having known anyone who participated in a CR (p<0.001). The significant predictors for willingness to participate in a CR were those living in villages as against those living in cities (p=0.002), belongs to Brahm Govind (BG) Prasad’s socioeconomic status class 1 (p=0.023) or class 4 (p=0.011) as against those in class 5, those who have heard about CR (p=0.023), participated in CR (p<0.001), have known someone participated in a CR (p<0.001) or higher total score of favourable perceptions (p<0.001).ConclusionsWhile there was extensive media coverage on drug/vaccine development processes during the COVID-19 pandemic, significant knowledge gaps and concerns regarding various aspects of CR persisted. Although some individuals showed a positive view of CR and its societal benefits, the overall public awareness remains insufficient. |
Author | Kureethara, Joseph Varghese Tomy, Suraj Kallarakal Raj, Jeffrey Pradeep Kallarakal, Tomy K Jose, Amrutha Kashyap, Aadrika |
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Cites_doi | 10.1186/s12910-017-0217-6 10.2147/PPA.S261903 10.4103/picr.PICR_97_19 10.3934/publichealth.2022018 10.4103/2229-3485.128018 10.1371/journal.pone.0010730 10.47263/JASEM.4(2)01 10.2196/37367 10.1038/s41539-018-0022-0 10.4172/2155-9627.1000201 10.1016/j.jesp.2009.03.009 10.1186/s12889-023-15928-w 10.1016/j.cct.2007.02.004 10.7759/cureus.10453 10.1371/journal.pone.0068666 10.1056/NEJMp048361 10.4103/ija.IJA_143_17 10.4103/jfmpc.jfmpc_1478_22 10.1017/gheg.2015.5 10.1186/s12874-021-01478-5 10.1371/journal.pone.0286968 10.4103/picr.PICR_208_19 |
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publication-title: PLoS One doi: 10.1371/journal.pone.0286968 contributor: fullname: Greul – volume: 18 year: 2017 ident: 2024080103212320000_2.1.e000748.4 article-title: Collaborative partnership and the social value of clinical research: a qualitative secondary analysis publication-title: BMC Med Ethics doi: 10.1186/s12910-017-0217-6 contributor: fullname: Nurmi – volume: 5 start-page: 1 year: 2014 ident: 2024080103212320000_2.1.e000748.2 article-title: Clinical research environment in India: challenges and proposed solutions publication-title: J Clin Res Bioeth contributor: fullname: Burt – volume: 12 start-page: 93 year: 2021 ident: 2024080103212320000_2.1.e000748.11 article-title: A survey of knowledge and variables influencing perceptions about clinical research: a cross-sectional study from Mumbai publication-title: Perspect Clin Res doi: 10.4103/picr.PICR_97_19 contributor: fullname: Figer – volume: 11 start-page: 37 year: 2020 ident: 2024080103212320000_2.1.e000748.23 article-title: New drugs and clinical trials rules 2019: changes in responsibilities of the ethics committee publication-title: Perspect Clin Res doi: 10.4103/picr.PICR_208_19 contributor: fullname: Singh – ident: 2024080103212320000_2.1.e000748.3 doi: 10.1056/NEJMp048361 – volume: 1 year: 2016 ident: 2024080103212320000_2.1.e000748.5 article-title: Regulatory developments in the conduct of clinical trials in India publication-title: Glob Health Epidemiol Genom doi: 10.1017/gheg.2015.5 contributor: fullname: Roy Chaudhury – volume: 5 year: 2010 ident: 2024080103212320000_2.1.e000748.21 article-title: What leads Indians to participate in clinical trials? A meta-analysis of qualitative studies publication-title: PLoS One doi: 10.1371/journal.pone.0010730 contributor: fullname: Shah |
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Snippet | IntroductionPrior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps. Thus,... Introduction Prior studies on public attitudes and awareness of clinical research (CR) in India before the pandemic identified significant knowledge gaps.... |
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Title | Knowledge and perceptions about clinical research and its ethical conduct among college students from non-science background: a representative nation-wide survey from India |
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