Phosphorylation of disordered proteins tunes local and global intramolecular interactions

• Published in: bioRxiv
• Main Authors: Usher, Emery T, Fossat, Martin J, Holehouse, Alex S
• Format: Journal Article Paper
• Language: English
• Published: United States Cold Spring Harbor Laboratory 12.06.2024
• Edition: 1.1
• Subjects: Biophysics

Protein post-translational modifications, such as phosphorylation, are important regulatory signals for diverse cellular functions. In particular, intrinsically disordered protein regions (IDRs) are subject to phosphorylation as a means to modulate their interactions and functions. Toward understand...