702 Phase 1 study of DLL3-directed chimeric antigen receptor T-cells in subjects with extensive stage small cell lung cancer

• Published in: Journal for immunotherapy of cancer Vol. 11; no. Suppl 1; p. A797
• Main Authors: Sands, Jacob, Schoenfeld, Adam, Schwarzenberger, Paul, delCorral, Christopher, Geng, Dong, Yun, Zhong, Wang, Chaun, Amato, Gianni, Vahora, Sahista, Pacaud, Lida, Hao, Zhonglin, Chiappori, Alberto
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd 01.11.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Cancer therapies; Chemotherapy; Immunotherapy; Ligands; Lung cancer; Regular and Young Investigator Award Abstracts; United States > US

BackgroundExtensive Stage Small Cell Lung Cancer (ES-SCLC) and Large Cell Neuroendocrine of the lung (LCNEC) are aggressive neuroendocrine carcinomas with an exceptionally poor prognosis.1 2 Although the majority of patients experience response to first line of therapy, the durability of response is...