772 Novel RNA-nanoparticle vaccine for the treatment of early melanoma recurrence following adjuvant anti-PD-1 antibody therapy

• Published in: Journal for immunotherapy of cancer Vol. 11; no. Suppl 1; pp. A867 - A869
• Main Authors: Doonan, Bently, Shaw, Christiana, Lee, Ji-Hyun, Manso, Eugenio, Mendez-Gomez, Hector, Roemeling, Christina Von, Mitchell, Duane A, Sayour, Elias
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd 01.11.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Antibodies; Immune checkpoint inhibitors; Immunotherapy; Lipids; Melanoma; Nanoparticles; Regular and Young Investigator Award Abstracts; Vaccines

BackgroundMelanoma is an increasing public health concern. Immune checkpoint inhibitors (ICI) has revolutionized the treatment of advanced melanoma. Unfortunately, in the adjuvant setting, up to 30% of subjects have disease recurrence within 1 year of treatment. Previous studies have shown that subj...