336 Long-term quality of life of out of hospital cardiac arrest (OHCA) survivors: feasibility of using EQ-5D-3L in an Asian population

• Published in: BMJ open Vol. 12; no. Suppl 1; p. A16
• Main Authors: Yang, X, Kwan, C, Pek, P, Lim, S, Shahidah, N, Graves, N, Siddiqui, FJ, Liu, N, Ho, A, Ong, M, Investigators, PAROSStudy
• Format: Journal Article
• Language: English
• Published: London British Medical Journal Publishing Group 01.05.2022; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Abstracts; Ambulance services; Asian people; Cardiac arrest; Cardiovascular disease; Clinical outcomes; Heart attacks; Longitudinal studies; Neurological disorders; Quality of life; Survivor
• ISSN: 2044-6055; 2044-6055
• DOI: 10.1136/bmjopen-2022-EMS.37

BackgroundThe purpose of this study was to evaluate the health-related Quality of Life (HRQoL) of OHCA survivors in Singapore using EQ-5D-3L and to assess the factors affecting survey response.MethodAdult OHCA patients aged >/= 18 years between April 2014 to December 2017 who survived to hospital discharge or 30 days were included in a retrospective follow-up study using data obtained from a national registry. EMS-witnessed arrests, those of a drowning or traumatic aetiology, or immediately pronounced dead at scene were excluded. Uncontactable and deceased patients at time of survey were deemed ineligible. The remaining were administered the EQ-5D-3L questionnaire via telephone follow-up at different time points.ResultsOf 2727 patients with ROSC, 368 (25%) survived to discharge or were alive at 30 days. At point of survey, 77 (20.9%) had passed away and 38 (10.3%) were uncontactable. Of the remaining 253, 121 (47.8%) refused and interviews were conducted with 132 (52.2% ) patients or proxies. The median follow-up time was 24.5 months (19.2, 33.3)The mean EQ5D index score was 0.77 (SD 0.44), 86 (65.7%) patients had a full score of 1. The mean EQ5D VAS score was 76.3 (SD17.6). Non-responders tended to be older (60.8 vs 54.9, p<0.003), and had poorer neurological status (CPC 3 or 4) (53.7% vs 35.6%, p<0.001).ConclusionMajority of the OHCA survivors interviewed had a good quality of life post-OHCA at time of follow-up. However, the study was limited by the low response rate, variable follow-up time and selection bias (responders vs non-responders). For future QoL studies, we recommend that follow-up time be standardised after OHCA. Other measurements of HRQoL should be explored in our population.Conflict of interestNo conflict of interests to declare.FundingNone.