Hepatoprotective effects of Aureobasidium pullulans derived Beta 1,3-1,6 biological response modifier glucans in a STAM- animal model of non-alcoholic steatohepatitis

• Published in: bioRxiv
• Main Authors: Ikewaki, Nobunao, Kurosawa, Gene, Iwasaki, Masaru, Preethy, Senthilkumar, Dedeepiya, Vidyasagar Devaprasad, Vaddi, Suryaprakash, Senthilkumar, Rajappa, Levy, Gary A, Abraham, Samuel JK
• Format: Paper
• Language: Japanese
• Published: Cold Spring Harbor Laboratory 09.07.2021
• Edition: 1.1
• Subjects: Pharmacology and Toxicology; Anti-fibrotic; Hepatoprotective; Non-alcoholic fatty liver disease (NAFLD); Beta glucans; Anti-inflammatory; Non-alcoholic steatohepatitis (NASH); Telmisartan

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are highly prevalent conditions characterized by inflammation and fibrosis of the liver which can progress to cirrhosis and hepatocellular carcinoma if left untreated. Lifestyle disorders such as obesity, diabetes and...