THU0103 Synovial plasma cells predict relapse after rituximab therapy in rheumatoid arthritis

• Published in: Annals of the rheumatic diseases Vol. 71; no. Suppl 3; p. 189
• Main Authors: Vital, E., El-Sherbiny, Y.M., Henshaw, K., Dass, S., Das, S., Buch, M., Ponchel, F., Emery, P.
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and European League Against Rheumatism 01.06.2013; BMJ Publishing Group LTD

Background Response to rituximab in patients with RA is followed by relapse after a variable interval. Previous studies have associated initial response to rituximab with lower numbers of CD79a+ B cells at baseline and CD138+ plasma cells at 16 weeks. We recently demonstrated that numbers of plasmab...