FRI0030 Jak2/stat3 is a major pathway of leptin-induced interleukin-6 production by rheumatoid synovial fibroblasts
Background Since proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6, play major pathophysiological roles in rheumatoid arthritis (RA), their inhibitors have recently been developed as potent biological anti-rheumatic drugs. However, they are not curat...
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Published in | Annals of the rheumatic diseases Vol. 72; no. Suppl 3; p. A378 |
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Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
London
BMJ Publishing Group Ltd and European League Against Rheumatism
01.06.2013
BMJ Publishing Group LTD |
Online Access | Get full text |
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