Intermolecular interactions play a role in the distribution and transport of charged contrast agents in a cartilage model

• Published in: bioRxiv
• Main Authors: Söderman, Olle, Algotsson, Jenny, Jönsson, Peter, sman, Jan, Topgaard, Daniel
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 27.03.2019; Cold Spring Harbor Laboratory
• Edition: 1.1
• Subjects: Biophysics; Cartilage (articular); Contrast agents; Electrostatic properties; Magnetic resonance imaging; NMR; Nuclear magnetic resonance; Polyelectrolytes; Solutes; Synovial fluid

The transport of charged solutes into articular cartilage through diffusion mechanism is important both for the maintaining of the metabolic function of the tissue, as well as for medical examinations of the cartilage status with help of contrast agents. The scientific issues include the rate of tra...