Regulation of gene expression by repression condensates during development

• Published in: bioRxiv
• Main Authors: Treen, Nicholas, Shimobayashi, Shunsuke F., Eeftens, Jorine, Brangwynne, Clifford P., Levine, Michael S.
• Format: Paper
• Language: English; Japanese
• Published: Cold Spring Harbor Laboratory 04.03.2020
• Edition: 1.1
• Subjects: Developmental Biology

There is emerging evidence for transcription condensates in the activation of gene expression1–3. However, there is considerably less information regarding transcriptional repression, despite its pervasive importance in regulating gene expression in development and disease. Here, we explore the role...