OP0058 Low-dose radiation therapy as treatment for hand and knee osteoarthritis: two double-blinded rct’s

• Published in: Annals of the rheumatic diseases Vol. 77; no. Suppl 2; p. 79
• Main Authors: Minten, M., Mahler, E., Leseman-Hoogenboom, M., Boks, S., Kloppenburg, M., Leer, J.W., Poortmans, P., van den Hoogen, F., den Broeder, A., van den Ende, C.
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.06.2018
• Subjects: Analgesics; Animal models; Arthritis; Clinical outcomes; Effusion; Hand; Inflammation; Joint diseases; Knee; Literature reviews; Magnetic resonance imaging; Osteoarthritis; Pain; Patients; Radiation therapy; Synovitis; Ultrasound

BackgroundSynovial inflammation plays an important role in osteoarthritis (OA) pathophysiology. In some countries, low-dose radiation therapy (LD-RT) is widely used as treatment for OA, while relatively unknown in others. Studies in vitro and in OA animal models have shown anti-inflammatory effects...