THU0445 The Change of Laboratory Markers in Serum Under the Influence of Inhibitor of Interleukin-1 in the Therapy of Secondary Osteoarthritis in Patients with Rheumatoid Arthritis

• Published in: Annals of the rheumatic diseases Vol. 74; no. Suppl 2; p. 361
• Main Authors: Starodubtseva, I., Vasilieva, L., Nikitin, A., Barsukova, N.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier Limited 01.06.2015

BackgroundDiacerein and its active metabolite, rhein, are anthraquinone derivatives. It is considered, that diacerein works by blocking/reducing the actions of interleukin-1β, a protein involved in the process of articular cartilage destruction and synovial inflammation 1-4.ObjectivesTo evaluate the...