4CPS-239 Therapeutic drug monitoring of gentamicin in neonates

• Published in: European journal of hospital pharmacy. Science and practice Vol. 28; no. Suppl 1; pp. A34 - A35
• Main Authors: Ortega-Garcia, MP, Zaragozá- González, M, Pérez-Villalón, P, Gil-Gómez, I, Moya-Gil Ana, A, Gómez-Bayona, E, Laguía-Sánchez, R, Blasco-Segura, P
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.03.2021
• Subjects: Conflicts of interest; Drug dosages

Background and importancePeak (maximum plasma concentration)/MIC >8–15 is a pharmacokinetic (PK)/pharmacodynamic (PD) parameter that best correlates with the effectiveness of aminoglycosides. A peak between 8 and 15 mg/L is necessary to achieve this. In neonates, doses of 3–5 mg/kg/day for the fi...