Impact of reinfection with SARS-CoV-2 Omicron variants in previously infected hamsters

• Published in: bioRxiv
• Main Authors: Shiwa-Sudo, Nozomi, Sakai, Yusuke, Iwata-Yoshikawa, Naoko, Watanabe, Shinji, Yamada, Souichi, Kuroda, Yudai, Yamamoto, Tsukasa, Shirakura, Masayuki, Fujisaki, Seiichiro, Miyazaki, Kaya, Miura, Hideka, Nagata, Shiho, Fukushi, Shuetsu, Maeda, Ken, Hasegawa, Hideki, Suzuki, Tadaki, Nagata, Noriyo
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 01.09.2022; Cold Spring Harbor Laboratory
• Edition: 1.2
• Subjects: Amino acids; Chemokines; Cytokines; Infections; Inflammation; Microbiology; Mutation; Replication; Respiratory tract diseases; RNA viruses; Severe acute respiratory syndrome coronavirus 2; Viral infections

The diversity of SARS-CoV-2 mutations raises the possibility of reinfection of individuals previously infected with earlier variants, and this risk is further increased by the emergence of the B.1.1.529 Omicron variant. In this study, we used an in vivo, hamster infection model to assess the potenti...