Proof of concept study to develop a novel connectivity-based electric-field modelling approach for individualized targeting of transcranial magnetic stimulation treatment

• Published in: bioRxiv
• Main Authors: Balderston, Nicholas L, Beer, Joanne C, Darsol Seok, Makhoul, Walid, Zhi-De Deng, Girelli, Tommaso, Teferi, Marta, Smyk, Nathan, Jaskir, Marc, Oathes, Desmond J, Sheline, Yvette I
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 19.03.2021; Cold Spring Harbor Laboratory
• Edition: 1.3
• Subjects: Magnetic fields; Neural networks; Neuroscience; Transcranial magnetic stimulation; Transcranial Magnetic Stimulation; anxiety; resting state; anxious misery; functional connectivity; depression; electric field modelling

Abstract Background Resting state functional connectivity (rsFC) offers promise for individualizing stimulation targets for transcranial magnetic stimulation (TMS) treatments. However current targeting approaches do not account for non-focal TMS effects or large-scale connectivity patterns. To overc...