Peri-adolescent THC exposure does not lead to anxiety-like behavior in adult mice

• Published in: bioRxiv
• Main Authors: Sestan-Pesa, Matija, Shanabrough, Marya, Horvath, Tamas L, Miletta, Maria Consolata
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 01.09.2020; Cold Spring Harbor Laboratory
• Edition: 1.1
• Subjects: Adolescents; Animal Behavior and Cognition; Animal models; Anxiety; Behavior; Cannabis; Child development; Feeding behavior; Genotypes; Ghrelin; Growth hormones; Mental depression; Mental disorders; Rodents; Schizophrenia; Tetrahydrocannabinol; THC; peri-adolescence; endocannabinoid system; GHSR signaling; Ghrelin; Tetrahydrocannabinol (THC)

Abstract As marijuana use during adolescence has been increasing, the need to understand the effects of its long-term use becomes crucial. Previous research suggested that marijuana consumption during adolescence increases the risk of developing mental illness, such as schizophrenia, depression, and...