CP-221 Clinical experience with intrathecal rituximab for treatment of progressive multiple sclerosis

• Published in: European journal of hospital pharmacy. Science and practice Vol. 24; no. Suppl 1; p. A99
• Main Authors: Robles, AA García, Albir, MJ Company, Vericat, JE Megías, Gascó, A Ferrada, Megía, MJ Fernández, Miralles, FC Pérez, Vicente, C Alcalá, Blasco, I Boscá, Andrés, JL Poveda, Estruch, B Casanova
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group LTD 01.03.2017
• Subjects: Immunotherapy; Lymphocytes; Monoclonal antibodies; Multiple sclerosis; Patients

BackgroundInaccessibility of inflammation compartmentalised to the CNS may underlie the lack of effectiveness of immunomodulatory treatments in progressive multiple sclerosis (PMS), turning its treatment into a challenge for researches. Intrathecal rituximab (IT-RTX) is a new treatment option which...