Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response

• Published in: Mediators of Inflammation Vol. 2015; no. 2015; pp. 137 - 147-011
• Main Authors: Griffith, David, Kurdowska, A., Baughman, Robert P., Torzewska, Agnieszka, Brzostek, Anna, Wojciechowska, Dominika, Kepka, Ewa, Dziadek, Bozena R., Fol, Marek, Krupa, Agnieszka, Dziadek, Jaroslaw
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Limiteds 01.01.2015; Hindawi Publishing Corporation; John Wiley & Sons, Inc; Wiley
• Subjects: Biology; Bronchoalveolar Lavage Fluid - immunology; Chemokines; Colleges & universities; Health aspects; Human subjects; Humans; Immune response; Immune system; Immunity, Innate; Infections; Infectious diseases; Interleukin-8; Interleukin-8 - analysis; Interleukin-8 - physiology; Lung - immunology; Lymphocytes; Medical research; Medicine, Experimental; Mycobacterium tuberculosis; Mycobacterium tuberculosis - immunology; Phagocytosis; Physiological aspects; Science; Tuberculosis

Interleukin-8 (IL-8) has been implicated in the pathogenesis of several human respiratory diseases, including tuberculosis (TB). Importantly and in direct relevance to the objectives of this report quite a few findings suggest that the presence of IL-8 may be beneficial for the host. IL-8 may aid wi...