MiR-195 Inhibits Tumor Growth and Metastasis in Papillary Thyroid Carcinoma Cell Lines by Targeting CCND1 and FGF2

• Published in: International Journal of Endocrinology Vol. 2017; no. 2017; pp. 1 - 12
• Main Authors: Xiao, Haipeng, Li, Yanbing, Liu, Yujie, Chen, Shuwei, Huang, Yanrui, Yu, Shuang, Hong, Shubin, Yin, Yali, Zhang, Quan
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Limiteds 01.01.2017; Hindawi Publishing Corporation; Hindawi; John Wiley & Sons, Inc; Wiley
• Subjects: Antibodies; Antigens; Cell adhesion & migration; Cloning; Development and progression; Endocrinology; Genes; Genetic aspects; Medical prognosis; Metastasis; MicroRNA; MicroRNAs; Pathogenesis; Plasmids; Thyroid cancer; United States > US; Switzerland; China; Germany

Background. MicroRNA (miRNA) dysregulation was commonly seen in papillary thyroid carcinoma (PTC), and miR-195 was verified to be downregulated in PTC by the large data set analysis from The Cancer Genome Atlas (TCGA). Our study aimed to explore the biological functions and the underlying molecular...