Expression of Reactive Oxygen Species-Related Transcripts in Egyptian Children With Autism

• Published in: Biomarker Insights Vol. 2017; pp. 1 - 9-003
• Main Authors: Meguid, Nagwa A, Ghozlan, Said A S, Mohamed, Magda F, Ibrahim, Marwa K, Dawood, Reham M, Bader El Din, Noha G, Abdelhafez, Tawfeek H, Hemimi, Maha, El Awady, Mostafa K
• Format: Journal Article
• Language: English
• Published: London, England Libertas Academica 2017; SAGE Publications; Sage Publications Ltd; SAGE Publishing
• Subjects: Amino acids; Antioxidants; Authorship; Autism; Biomarkers; Children; Children & youth; Diagnostic tests; Enzymes; Experiments; Families & family life; Gene expression; Genetic factors; Medical research; Medical screening; Original Research; Oxidative stress; Peer review; Peripheral blood; Polymerase chain reaction; Proteins; Reactive oxygen species; Studies; Superoxide dismutase; Transcription; Egypt; Autism; neurodevelopmental disorders; gene expression; oxidative stress; ROS; PCR array

The molecular basis of the pathophysiological role of oxidative stress in autism is understudied. Herein, we used polymerase chain reaction (PCR) array to analyze transcriptional pattern of 84 oxidative stress genes in peripheral blood mononuclear cell pools isolated from 32 autistic patients (16 mi...