Relationship between structure and convulsant properties of some beta-lactam antibiotics following intracerebroventricular microinjection in rats

• Published in: Antimicrobial Agents and Chemotherapy Vol. 39; no. 1; pp. 232 - 237
• Main Authors: DE SARRO, A, AMMENDOLA, D, ZAPPALA, M, GRASSO, S, DE SARRO, G. B
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.01.1995
• Subjects: Animals; Anti-Bacterial Agents; Anti-Bacterial Agents - pharmacology; beta-Lactams; Biological and medical sciences; Comparative Study; Dose-Response Relationship, Drug; Drug toxicity and drugs side effects treatment; Injections, Intraventricular; Male; Medical sciences; Pharmacology. Drug treatments; Rats; Rats, Wistar; Research Support, Non-U.S. Gov't; Seizures; Seizures - chemically induced; Structure-Activity Relationship; Toxicity: nervous system and muscle; Rat; Toxicity; Rodentia; Lactam; Vertebrata; Antibiotic; Mammalia; Convulsion; Structure activity relation; Animal; Intracerebral administration; Neurological disorder; Antibacterial agent
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.39.1.232

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