Tissue Tregs

• Published in: Annual review of immunology Vol. 34; no. 1; pp. 609 - 633
• Main Authors: Panduro, Marisella, Benoist, Christophe, Mathis, Diane
• Format: Journal Article
• Language: English
• Published: United States Annual Reviews 20.05.2016
• Subjects: adipose tissue; Adipose Tissue - immunology; Animals; Colon - immunology; Forkhead Transcription Factors - metabolism; Homeostasis; Humans; metabolism; microbiota; mucosal immunology; Mucous Membrane - immunology; Muscle, Skeletal - immunology; Organ Specificity; skeletal muscle; T-Lymphocytes, Regulatory - immunology; tissue repair; microbiota; adipose tissue; mucosal immunology; metabolism; skeletal muscle; tissue repair

The immune system is responsible for defending an organism against the myriad of microbial invaders it constantly confronts. It has become increasingly clear that the immune system has a second major function: the maintenance of organismal homeostasis. Foxp3 + CD4 + regulatory T cells (Tregs) are im...