Handbook of Heterocyclic Chemistry (3rd Edition)
Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, this book is thoroug...
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| Main Author | |
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| Format | eBook Book |
| Language | English |
| Published |
Oxford ; Tokyo
Elsevier
2010
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| Edition | 3 |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, this book is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. |
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| AbstractList | Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course.
-Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work -Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts -Features 35% new material to compliment the completely revised text Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, this book is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. |
| Author | Zhdankin Viktor V Ramsden Christopher A Katritzky Alan R Joule John A |
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| Copyright | 2010 |
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| DOI | 10.1016/C2009-0-05547-0 |
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| Discipline | Chemistry |
| EISBN | 9780080958446 0080958443 |
| Edition | 3 3rd ed. |
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| Notes | Includes bibliographical references (p. 917-970) and index Previous ed.: 2000 |
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| Snippet | Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse... |
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| SubjectTerms | Chemistry & Chemical Engineering General References Handbooks, manuals, etc Heterocyclic chemistry |
| TableOfContents | Title Page
Notes on the Arrangement of the Material in the Handbook
Explanation of the Reference System
Table of Contents
2.1 Overview
2.2 Structure of Six-Membered Rings
2.3 Structure of Five-Membered Rings with One Heteroatom
2.4 Structure of Five-Membered Rings with Two or More Heteroatoms
2.5 Structure of Small and Large Rings
3.1 Overview
3.2 Reactivity of Six-Membered Rings
3.3 Reactivity of Five-Membered Rings with One Heteroatom
3.4 Reactivity of Five-Membered Rings with Two or More Heteroatoms
3.5 Reactivity of Small and Large Rings
4.1 Overview
4.2 Synthesis of Monocyclic Rings with One Heteroatom
4.3 Synthesis of Monocyclic Rings with Two or More Heteroatoms
4.4 Synthesis of Bicyclic Ring Systems without Ring Junction Heteroatoms
4.5 Synthesis of Tri- and Polycyclic Ring Systems without Ring Junction Heteroatoms
4.6 Synthesis of Fused Ring Systems with Ring Junction Heteroatoms
References
Index
Journal Abbreviations 4.4.1 Synthesis by Substituent Introduction and Modification -- 4.4.2 One Heteroatom Adjacent to a Ring Junction -- 4.4.3 One Heteroatom Not Adjacent to a Ring Junction -- 4.4.4 Two Heteroatoms 1,2 to a Ring Junction -- 4.4.5 Two Heteroatoms 1,3 to a Ring Junction -- 4.4.6 Two Heteroatoms 1,4 to a Ring Junction -- 4.4.7 Two Heteroatoms 2,3 to a Ring Junction -- 4.4.8 Three or More Heteroatoms -- 4.5 Synthesis of Tri- and Polycyclic Ring Systems Without Ring Junction Heteroatoms -- 4.5.1 Two Adjacent Fused Rings, One Heteroatom -- 4.5.2 Two Adjacent Fused Rings, Two Heteroatoms -- 4.5.3 Two Nonadjacent Fused Rings, One Heteroatom -- 4.5.4 Two Nonadjacent Fused Rings, Two Heteroatoms -- 4.5.5 peri-Annulated Heterocyclic Systems -- 4.5.6 Three Fused Rings -- 4.6 Synthesis of Fused Ring Systems with Ring Junction Heteroatoms -- 4.6.1 Formation of Three- or Four-Membered Rings with One N Atom at a Ring Junction -- 4.6.2 Formation of a Five-Membered Ring with One N Atom at a Ring Junction -- 4.6.3 Formation of a Six-Membered Ring with One N Atom at a Ring Junction -- 4.6.4 Formation of a Seven-Membered Ring with One N Atom at a Ring Junction -- 4.6.5 Two Nitrogen Atoms at a Ring Junction -- 4.6.6 Sulfur at a Ring Junction -- References -- Index -- Journal Abbreviations Cover -- Handbook of Heter ocylic Chemistry -- Copyright -- Part 1 Preliminaries -- 1.1 Foreword -- 1.2 Detailed Contents -- 1.3 Notes on the Arrangement of the Material in the Handbook -- 1.4 Explanation of the Reference System -- Part 2 Structure of Heterocycles -- 2.1 Overview -- 2.1.1 Relationship of Heterocyclic and Carbocyclic Aromatic Compounds -- 2.1.2 Arrangement of Structure Chapters -- 2.1.3 Nomenclature -- 2.1.4 Computer-Aided Studies of Heterocycles -- 2.1.5 Glossary of General Terms Used in Chapters 2.2-2.5 -- 2.2 Structure of Six-membered Rings -- 2.2.1 Survey of Possible Structures and Nomenclature -- 2.2.2 Theoretical Methods -- 2.2.3 Structural Methods -- 2.2.4 Thermodynamic Aspects -- 2.2.5 Tautomerism -- 2.2.6 Supramolecular Structures -- 2.3 Structure of Five-Membered Rings with One Heteroatom -- 2.3.1 Survey of Possible Structures and Nomenclature -- 2.3.2 Theoretical Methods -- 2.3.3 Structural Methods -- 2.3.4 Thermodynamic Aspects -- 2.3.5 Tautomerism -- 2.4 Structure of Five-membered Rings with Two or More Heteroatoms -- 2.4.1 Survey of Possible Structures and Nomenclature -- 2.4.2 Theoretical Methods -- 2.4.3 Structural Methods -- 2.4.4 Thermodynamic Aspects -- 2.4.5 Tautomerism -- 2.5 Structure of Small and Large Rings -- 2.5.1 Survey of Possible Structures and Nomenclature -- 2.5.2 Theoretical Methods -- 2.5.3 Structural Methods -- 2.5.4 Thermodynamic Aspects -- 2.5.5 Tautomerism -- Part 3 Reactivity of Heterocycles -- 3.1 Overview -- 3.1.1 Reaction Types -- 3.1.2 Heteroaromatic Reactivity -- 3.1.3 Arrangement of the Reactivity Sections -- 3.2 Reactivity of Six-membered Rings -- 3.2.1 Reactivity of Aromatic Rings -- 3.2.2 Reactions of Nonaromatic Compounds -- 3.2.3 Reactions of Substituents -- 3.3 Reactivity of Five-Membered Rings with One Heteroatom -- 3.3.1 Reactions at Heteroaromatic Rings 3.3.2 Reactivity of Nonaromatic Compounds -- 3.3.3 Reactivity of Substituents -- 3.4 Reactivity of Five-membered Rings with Two or More Heteroatoms -- 3.4.1 Reactions at Heteroaromatic Rings -- 3.4.2 Reactions of Nonaromatic Compounds -- 3.4.3 Reactions of Substituents -- 3.5 Reactivity of Small and Large Rings -- 3.5.1 General Survey -- 3.5.2 Thermal and Photochemical Reactions, Not Formally Involving Other Species -- 3.5.3 Electrophilic Attack on Ring Heteroatoms -- 3.5.4 Nucleophilic Attack on Ring Heteroatoms -- 3.5.5 Nucleophilic Attack on Ring Carbon Atoms -- 3.5.6 Base Attack on Protons Attached to Ring Atoms -- 3.5.7 Attack by Radicals or Electron-Deficient Species. Oxidation and Reduction -- 3.5.8 Reactions with Cyclic Transition States -- 3.5.9 Reactivity of Transition Metal Complexes -- 3.5.10 Reactivity of Substituents Attached to Heteroatom or Ring Carbon Atoms -- 4 Synthesis of Heterocycles -- 4.1 Overview -- 4.1.1 Aims and Organization -- 4.1.2 Ring Formation from Two Components -- 4.1.3 Ring Closure of a Single Component -- 4.1.4 Modification of an Existing Ring -- 4.2 Synthesis of Monocyclic Rings with One Heteroatom -- 4.2.1 Rings Containing No Endocyclic Double Bonds -- 4.2.2 Rings Containing One Endocyclic Double Bond -- 4.2.3 Rings Containing Two Endocyclic Double Bonds -- 4.2.4 Rings Containing Three Endocyclic Double Bonds -- 4.3 Synthesis of Monocyclic Rings with Two or More Heteroatoms -- 4.3.1 Substituent Introduction and Modification -- 4.3.2 Two Heteroatoms in the 1,2-Positions -- 4.3.3 Two Heteroatoms in the 1,3-Positions -- 4.3.4 Two Heteroatoms in the 1,4-Positions -- 4.3.5 Three Heteroatoms in the 1,2,3-Positions -- 4.3.6 Three Heteroatoms in the 1,2,4-Positions -- 4.3.7 Three Heteroatoms in the 1,3,5-Positions -- 4.3.8 Four or More Heteroatoms -- 4.4 Synthesis of Bicyclic Ring Systems Without Ring Junction Heteroatoms |
| Title | Handbook of Heterocyclic Chemistry (3rd Edition) |
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