Liver Progenitors and Adult Cell Plasticity in Hepatic Injury and Repair: Knowns and Unknowns

• Published in: Annual review of pathology Vol. 15; p. 23
• Main Authors: Ko, Sungjin, Russell, Jacquelyn O, Molina, Laura M, Monga, Satdarshan P
• Format: Journal Article
• Language: English
• Published: United States 24.01.2020
• Subjects: Adult Stem Cells - physiology; Animals; Cell Differentiation; Cell Plasticity - physiology; End Stage Liver Disease - etiology; End Stage Liver Disease - physiopathology; Hepatocytes - physiology; Humans; Liver - injuries; Liver - physiology; Liver Diseases - physiopathology; Regeneration - physiology; Stem Cells - physiology; oval cell; ductular reaction; liver stem cell; liver cancer; liver regeneration

The liver is a complex organ performing numerous vital physiological functions. For that reason, it possesses immense regenerative potential. The capacity for repair is largely attributable to the ability of its differentiated epithelial cells, hepatocytes and biliary epithelial cells, to proliferat...