Suppression of Murine Endotoxin Response by E5531, a Novel Synthetic Lipid A Antagonist

• Published in: Antimicrobial Agents and Chemotherapy Vol. 42; no. 11; pp. 2824 - 2829
• Main Authors: KOBAYASHI, S, KAWATA, T, KIMURA, A, MIYAMOTO, K, KATAYAMA, K, YAMATSU, I, ROSSIGNOL, D. P, CHRIST, W. J, KISHI, Y
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.11.1998
• Subjects: Animals; Biologic Response Modifiers; Biological and medical sciences; Bones, joints and connective tissue. Antiinflammatory agents; Lipid A; Lipid A - analogs & derivatives; Lipid A - antagonists & inhibitors; Lipid A - pharmacology; Lipopolysaccharides; Lipopolysaccharides - antagonists & inhibitors; Lipopolysaccharides - metabolism; Liver - drug effects; Male; Medical sciences; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pharmacology. Drug treatments; Tumor Necrosis Factor-alpha - metabolism; Toxicity; Liver; Rodentia; Antiinflammatory agent; Cytokine; Lipids; Activation; Endotoxin; In vitro; In vivo; Vertebrata; Mammalia; Mouse; Animal; Lipopolysaccharide; Digestive diseases; Antagonist; Mechanism of action; Tumor necrosis factor α; Macrophage; Biological receptor
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/aac.42.11.2824

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