Calcium Density of Coronary Artery Plaque and Risk of Incident Cardiovascular Events

• Published in: JAMA : the journal of the American Medical Association Vol. 311; no. 3; pp. 271 - 278
• Main Authors: Criqui, Michael H, Denenberg, Julie O, Ix, Joachim H, McClelland, Robyn L, Wassel, Christina L, Rifkin, Dena E, Carr, Jeffrey J, Budoff, Matthew J, Allison, Matthew A
• Format: Journal Article
• Language: English
• Published: Chicago, IL American Medical Association 15.01.2014
• Subjects: Aged; Aged, 80 and over; Atherosclerosis (general aspects, experimental research); Atherosclerosis - diagnostic imaging; Biological and medical sciences; Blood and lymphatic vessels; Calcium; Calcium - analysis; Cardiology. Vascular system; Cardiovascular disease; Coronary Disease - epidemiology; Coronary Disease - prevention & control; Coronary Vessels - chemistry; Coronary Vessels - diagnostic imaging; Coronary Vessels - pathology; Female; General aspects; Humans; Male; Medical research; Medical sciences; Middle Aged; Plaque, Atherosclerotic - chemistry; Predictive Value of Tests; Prospective Studies; Reference Values; Risk; Tomography, X-Ray Computed; Mishap; Calcium; Coronary artery; Cardiovascular disease; Risk; Inorganic element; Density; Incidence; Vascular disease; Medicine; Atherosclerotic plaque; Atherosclerosis; Risk factor

IMPORTANCE Coronary artery calcium (CAC), measured by computed tomography (CT), has strong predictive value for incident cardiovascular disease (CVD) events. The standard CAC score is the Agatston, which is weighted upward for greater calcium density. However, some data suggest increased plaque calc...