Comparative Genomic Analysis Provides Insights into the Evolution and Genetic Diversity of Community-Genotype Sequence Type 72 Staphylococcus aureus Isolates
Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea, has emerged as a major cause of bloodstream infection in hospital settings. However, relatively little information is available regarding th...
Saved in:
Published in | mSystems Vol. 6; no. 5; p. e0098621 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
1752 N St., N.W., Washington, DC
American Society for Microbiology
26.10.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea, has emerged as a major cause of bloodstream infection in hospital settings. However, relatively little information is available regarding the genomic characteristics and dissemination of ST72. Here, we characterized the whole-genome sequence of 24 ST72 isolates from China, along with 83 ST72 genomes from global sources. Of these 107 ST72 isolates, 63 were MRSA and 44 were methicillin-susceptible S. aureus (MSSA). Phylogenetic analysis revealed four distinct clades (A, B, C, and D), of which clade D contained only MSSA isolates. By characterizing the evolutionary dynamics of the ST72 lineage, we found that the MRSA from China might not have developed from the MSSA in China. Furthermore, we observed both international transmission of ST72 isolates and interregional transmission within China. The distributions of the SCCmec and spa types of isolates differed among clades. Additionally, in silico analyses revealed that the distributions of resistance genes, virulence genes, and mobile genetic elements (MGEs) also differed among isolates of the four clades. This was especially true for clade D isolates, which had the lowest level of antimicrobial resistance and had obtained specific virulence genes such as tsst-1 by acquisition of specific MGEs. Notably, ST72 MRSA isolates were more antibiotic resistant than ST72 MSSA isolates, but comparably virulent. Our findings provide insight into the potential transmission and genotypic features of ST72 clones across the globe. IMPORTANCE Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage. We found that the MSSA lineage in China might have evolved independently from the MRSA isolates from China, and that ST72 isolates have the potential to undergo both international transmission and interregional transmission within China. The diversity of isolates correlated with distinct acquisitions of SCCmec elements, antibiotic resistance genes, virulence genes, and mobile genetic elements. The comprehensive information on the ST72 lineage emerging from this study will enable improved therapeutic approaches and rapid molecular diagnosis. |
---|---|
AbstractList | Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage.
ABSTRACT Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea, has emerged as a major cause of bloodstream infection in hospital settings. However, relatively little information is available regarding the genomic characteristics and dissemination of ST72. Here, we characterized the whole-genome sequence of 24 ST72 isolates from China, along with 83 ST72 genomes from global sources. Of these 107 ST72 isolates, 63 were MRSA and 44 were methicillin-susceptible S. aureus (MSSA). Phylogenetic analysis revealed four distinct clades (A, B, C, and D), of which clade D contained only MSSA isolates. By characterizing the evolutionary dynamics of the ST72 lineage, we found that the MRSA from China might not have developed from the MSSA in China. Furthermore, we observed both international transmission of ST72 isolates and interregional transmission within China. The distributions of the SCC mec and spa types of isolates differed among clades. Additionally, in silico analyses revealed that the distributions of resistance genes, virulence genes, and mobile genetic elements (MGEs) also differed among isolates of the four clades. This was especially true for clade D isolates, which had the lowest level of antimicrobial resistance and had obtained specific virulence genes such as tsst-1 by acquisition of specific MGEs. Notably, ST72 MRSA isolates were more antibiotic resistant than ST72 MSSA isolates, but comparably virulent. Our findings provide insight into the potential transmission and genotypic features of ST72 clones across the globe. IMPORTANCE Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage. We found that the MSSA lineage in China might have evolved independently from the MRSA isolates from China, and that ST72 isolates have the potential to undergo both international transmission and interregional transmission within China. The diversity of isolates correlated with distinct acquisitions of SCC mec elements, antibiotic resistance genes, virulence genes, and mobile genetic elements. The comprehensive information on the ST72 lineage emerging from this study will enable improved therapeutic approaches and rapid molecular diagnosis. Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea, has emerged as a major cause of bloodstream infection in hospital settings. However, relatively little information is available regarding the genomic characteristics and dissemination of ST72. Here, we characterized the whole-genome sequence of 24 ST72 isolates from China, along with 83 ST72 genomes from global sources. Of these 107 ST72 isolates, 63 were MRSA and 44 were methicillin-susceptible S. aureus (MSSA). Phylogenetic analysis revealed four distinct clades (A, B, C, and D), of which clade D contained only MSSA isolates. By characterizing the evolutionary dynamics of the ST72 lineage, we found that the MRSA from China might not have developed from the MSSA in China. Furthermore, we observed both international transmission of ST72 isolates and interregional transmission within China. The distributions of the SCC mec and spa types of isolates differed among clades. Additionally, in silico analyses revealed that the distributions of resistance genes, virulence genes, and mobile genetic elements (MGEs) also differed among isolates of the four clades. This was especially true for clade D isolates, which had the lowest level of antimicrobial resistance and had obtained specific virulence genes such as tsst-1 by acquisition of specific MGEs. Notably, ST72 MRSA isolates were more antibiotic resistant than ST72 MSSA isolates, but comparably virulent. Our findings provide insight into the potential transmission and genotypic features of ST72 clones across the globe. IMPORTANCE Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage. We found that the MSSA lineage in China might have evolved independently from the MRSA isolates from China, and that ST72 isolates have the potential to undergo both international transmission and interregional transmission within China. The diversity of isolates correlated with distinct acquisitions of SCC mec elements, antibiotic resistance genes, virulence genes, and mobile genetic elements. The comprehensive information on the ST72 lineage emerging from this study will enable improved therapeutic approaches and rapid molecular diagnosis. Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage. ABSTRACT Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea, has emerged as a major cause of bloodstream infection in hospital settings. However, relatively little information is available regarding the genomic characteristics and dissemination of ST72. Here, we characterized the whole-genome sequence of 24 ST72 isolates from China, along with 83 ST72 genomes from global sources. Of these 107 ST72 isolates, 63 were MRSA and 44 were methicillin-susceptible S. aureus (MSSA). Phylogenetic analysis revealed four distinct clades (A, B, C, and D), of which clade D contained only MSSA isolates. By characterizing the evolutionary dynamics of the ST72 lineage, we found that the MRSA from China might not have developed from the MSSA in China. Furthermore, we observed both international transmission of ST72 isolates and interregional transmission within China. The distributions of the SCC mec and spa types of isolates differed among clades. Additionally, in silico analyses revealed that the distributions of resistance genes, virulence genes, and mobile genetic elements (MGEs) also differed among isolates of the four clades. This was especially true for clade D isolates, which had the lowest level of antimicrobial resistance and had obtained specific virulence genes such as tsst-1 by acquisition of specific MGEs. Notably, ST72 MRSA isolates were more antibiotic resistant than ST72 MSSA isolates, but comparably virulent. Our findings provide insight into the potential transmission and genotypic features of ST72 clones across the globe. IMPORTANCE Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage. We found that the MSSA lineage in China might have evolved independently from the MRSA isolates from China, and that ST72 isolates have the potential to undergo both international transmission and interregional transmission within China. The diversity of isolates correlated with distinct acquisitions of SCC mec elements, antibiotic resistance genes, virulence genes, and mobile genetic elements. The comprehensive information on the ST72 lineage emerging from this study will enable improved therapeutic approaches and rapid molecular diagnosis. Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea, has emerged as a major cause of bloodstream infection in hospital settings. However, relatively little information is available regarding the genomic characteristics and dissemination of ST72. Here, we characterized the whole-genome sequence of 24 ST72 isolates from China, along with 83 ST72 genomes from global sources. Of these 107 ST72 isolates, 63 were MRSA and 44 were methicillin-susceptible S. aureus (MSSA). Phylogenetic analysis revealed four distinct clades (A, B, C, and D), of which clade D contained only MSSA isolates. By characterizing the evolutionary dynamics of the ST72 lineage, we found that the MRSA from China might not have developed from the MSSA in China. Furthermore, we observed both international transmission of ST72 isolates and interregional transmission within China. The distributions of the SCCmec and spa types of isolates differed among clades. Additionally, in silico analyses revealed that the distributions of resistance genes, virulence genes, and mobile genetic elements (MGEs) also differed among isolates of the four clades. This was especially true for clade D isolates, which had the lowest level of antimicrobial resistance and had obtained specific virulence genes such as tsst-1 by acquisition of specific MGEs. Notably, ST72 MRSA isolates were more antibiotic resistant than ST72 MSSA isolates, but comparably virulent. Our findings provide insight into the potential transmission and genotypic features of ST72 clones across the globe. IMPORTANCE Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly spread into hospital settings and caused serious health issues. In this study, we first carried out genome-wide analysis of 107 global ST72 isolates to characterize the evolution and genetic diversity of the ST72 lineage. We found that the MSSA lineage in China might have evolved independently from the MRSA isolates from China, and that ST72 isolates have the potential to undergo both international transmission and interregional transmission within China. The diversity of isolates correlated with distinct acquisitions of SCCmec elements, antibiotic resistance genes, virulence genes, and mobile genetic elements. The comprehensive information on the ST72 lineage emerging from this study will enable improved therapeutic approaches and rapid molecular diagnosis. Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus |
Author | Xiong, Luying Zhou, Wangxiao Jin, Ye Luo, Qixia Wang, Yuan Xiao, Yonghong Zhou, Yanzi |
Author_xml | – sequence: 1 givenname: Wangxiao surname: Zhou fullname: Zhou, Wangxiao organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China – sequence: 2 givenname: Ye surname: Jin fullname: Jin, Ye organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China – sequence: 3 givenname: Yanzi surname: Zhou fullname: Zhou, Yanzi organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China – sequence: 4 givenname: Yuan surname: Wang fullname: Wang, Yuan organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China – sequence: 5 givenname: Luying surname: Xiong fullname: Xiong, Luying organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China – sequence: 6 givenname: Qixia surname: Luo fullname: Luo, Qixia organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China – sequence: 7 givenname: Yonghong surname: Xiao fullname: Xiao, Yonghong organization: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China |
BookMark | eNqNkt9qHCEUh4eS0qRpHqB3XvZmth7nj-NNIaRpuhBoYdNrcZ3jrsuMbtVZmIfJu9bNhtJQKMWL41G_T5Tf2-LMeYdF8R7oAoB1H8fVHBOOcUGp6NqSwaviglVclA3l_OyP-XlxFeOOUgptxYGJN8V5VdcCaNdcFI83ftyroJI9ILlD50erybVTwxxtJN-DP9geI1m6aDfbFIl1yZO0RXJ78MOUrHdEuf5IYsrk56wJ0aaZeEOyepxcbsqjOM17JCv8OaHTSB6OHWdkldR-Ow9ee62nSNQUMJdl9INKGN8Vr40aIl4918vix5fbh5uv5f23u-XN9X2pGg6p5JxyJlS9XpsO81A9Nz3VpjW8FWveVBpAN4AalBC8Ea2hhlJmRNMYjqCry2J58vZe7eQ-2FGFWXpl5dOCDxupQn7fgFLoFgA61bYM6xYqURlV9Y0RNXCq11V2fTq59tN6xF6jS0ENL6Qvd5zdyo0_yK6pec1EFnx4FgSffysmOdqocRiUQz9FyRpOgQom6nwUTkd18DEGNL-vASqPKZFjPKVEPqVEMvgfZvU3szgxKo5M7vwUckLiP4Bf4WPWmw |
CitedBy_id | crossref_primary_10_1016_j_crfs_2023_100669 crossref_primary_10_1128_spectrum_04209_22 crossref_primary_10_1186_s12866_023_03027_0 crossref_primary_10_1128_spectrum_05351_22 crossref_primary_10_3389_fmicb_2023_1198200 crossref_primary_10_1016_j_jiac_2023_10_020 crossref_primary_10_1093_jac_dkad250 crossref_primary_10_1128_spectrum_00342_22 |
Cites_doi | 10.1056/NEJM199808203390806 10.1093/infdis/jir441 10.1073/pnas.1202869109 10.1002/cpbi.102 10.1093/nar/gky783 10.1093/jac/dkx200 10.1038/s41598-018-20661-1 10.1586/edm.10.6 10.1093/jac/dkm309 10.1093/cid/ciz621 10.1128/JCM.00590-12 10.1093/jac/dku475 10.1080/22221751.2020.1868950 10.1001/jama.290.22.2976 10.1186/s13059-016-1108-8 10.1590/s0074-02762011000800013 10.1186/1471-2334-14-459 10.1146/annurev.micro.112408.134309 10.1016/j.ijmm.2013.02.007 10.1001/jama.279.8.593 10.1038/srep27899 10.1016/S0140-6736(02)08713-5 10.1086/593953 10.1007/s12275-016-6157-x 10.1093/infdis/jiu462 10.1093/nar/gku1196 10.2147/IDR.S307856 10.1073/pnas.1401006111 10.1093/molbev/msz257 10.1016/j.jhin.2016.03.012 10.1093/bioinformatics/btu033 10.1111/j.1574-695X.2012.00937.x 10.1128/mBio.00802-17 10.1093/bioinformatics/btu153 10.1101/gr.147710.112 |
ContentType | Journal Article |
Copyright | Copyright © 2021 Zhou et al. Copyright © 2021 Zhou et al. 2021 Zhou et al. |
Copyright_xml | – notice: Copyright © 2021 Zhou et al. – notice: Copyright © 2021 Zhou et al. 2021 Zhou et al. |
DBID | AAYXX CITATION 7X8 5PM DOA |
DOI | 10.1128/mSystems.00986-21 |
DatabaseName | CrossRef MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
DatabaseTitle | CrossRef MEDLINE - Academic |
DatabaseTitleList | CrossRef CrossRef |
Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Biology |
EISSN | 2379-5077 |
Editor | Yildirim, Suleyman |
Editor_xml | – sequence: 1 givenname: Suleyman surname: Yildirim fullname: Yildirim, Suleyman |
EndPage | e0098621 |
ExternalDocumentID | oai_doaj_org_article_9c61118a662e461393fa3d5f94170cb3 10_1128_msystems_00986_21 10_1128_mSystems_00986_21 mSystems00986-21 |
GrantInformation_xml | – fundername: MOST | National Key Research and Development Program of China (973 Program) grantid: 2017YFC1200203 funderid: https://doi.org/10.13039/501100012166 – fundername: National Natural Science Foundation of China (NSFC) grantid: 81971984 funderid: https://doi.org/10.13039/501100001809 – fundername: ; grantid: 2017YFC1200203 – fundername: ; grantid: 81971984 |
GroupedDBID | 0R 3V. 53G 5VS 7X7 8FE 8FH 8FI 8FJ AAUOK ABUWG ADACO ADBBV AFKRA ALMA_UNASSIGNED_HOLDINGS AOIJS BBAFP BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI BXI EBS FYUFA GROUPED_DOAJ HCIFZ HYE KQ8 LK8 M48 M7P O9- OK1 PIMPY PQEST PQQKQ PQUKI PRINS PROAC RHI RPM RSF 0R~ AAFWJ AAYXX ACPRK AFPKN AHMBA ALIPV CCPQU CITATION FRP H13 HMCUK M~E UKHRP 7X8 5PM |
ID | FETCH-LOGICAL-a571t-770729a4bbf8e8e8ad7fd0cf6f769b753c11c51ec1a997596f0f002f955f7e1c3 |
IEDL.DBID | RPM |
ISSN | 2379-5077 |
IngestDate | Thu Sep 05 15:45:22 EDT 2024 Tue Sep 17 21:23:28 EDT 2024 Fri Aug 16 21:48:10 EDT 2024 Fri Aug 23 04:24:19 EDT 2024 Fri Aug 23 02:04:37 EDT 2024 Tue Dec 28 13:58:56 EST 2021 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 5 |
Keywords | transmission virulence antimicrobial resistance evolutionary dynamics mobile genetic elements Staphylococcus aureus sequence type 72 |
Language | English |
License | This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. https://creativecommons.org/licenses/by/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-a571t-770729a4bbf8e8e8ad7fd0cf6f769b753c11c51ec1a997596f0f002f955f7e1c3 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Authors Wangxiao Zhou, Ye Jin, and Yanzi Zhou contributed equally to this work. Author order was determined in order of increasing seniority. Citation Zhou W, Jin Y, Zhou Y, Wang Y, Xiong L, Luo Q, Xiao Y. 2021. Comparative genomic analysis provides insights into the evolution and genetic diversity of community-genotype sequence type 72 Staphylococcus aureus isolates. mSystems 6:e00986-21. https://doi.org/10.1128/mSystems.00986-21. |
OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547429/ |
PMID | 34491085 |
PQID | 2570109294 |
PQPubID | 23479 |
PageCount | 16 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_9c61118a662e461393fa3d5f94170cb3 pubmedcentral_primary_oai_pubmedcentral_nih_gov_8547429 proquest_miscellaneous_2570109294 crossref_primary_10_1128_msystems_00986_21 crossref_primary_10_1128_mSystems_00986_21 asm2_journals_10_1128_mSystems_00986_21 |
PublicationCentury | 2000 |
PublicationDate | 20211026 |
PublicationDateYYYYMMDD | 2021-10-26 |
PublicationDate_xml | – month: 10 year: 2021 text: 20211026 day: 26 |
PublicationDecade | 2020 |
PublicationPlace | 1752 N St., N.W., Washington, DC |
PublicationPlace_xml | – name: 1752 N St., N.W., Washington, DC |
PublicationTitle | mSystems |
PublicationTitleAbbrev | mSystems |
PublicationYear | 2021 |
Publisher | American Society for Microbiology |
Publisher_xml | – name: American Society for Microbiology |
References | Yu, Y, Blair, C, He, X (B34) 2020; 37 Baba, T, Takeuchi, F, Kuroda, M, Yuzawa, H, Aoki, K-i, Oguchi, A, Nagai, Y, Iwama, N, Asano, K, Naimi, T, Kuroda, H, Cui, L, Yamamoto, K, Hiramatsu, K (B9) 2002; 359 Otto, M (B1) 2010; 5 Kim, ES, Song, JS, Lee, HJ, Choe, PG, Park, KH, Cho, JH, Park, WB, Kim, S-H, Bang, J-H, Kim, D-M, Park, KU, Shin, S, Lee, MS, Choi, HJ, Kim, NJ, Kim, E-C, Oh, M-D, Kim, HB, Choe, KW (B14) 2007; 60 Prjibelski, A, Antipov, D, Meleshko, D, Lapidus, A, Korobeynikov, A (B30) 2020; 70 Yang, X, Zhao, J, Wang, Y, Wu, J, Wang, X, Wang, Y, Zhang, Y, Li, H (B19) 2021; 14 Uhlemann, A-C, Dordel, J, Knox, JR, Raven, KE, Parkhill, J, Holden, MT, Peacock, SJ, Lowy, FD (B21) 2014; 111 Jiménez, JN, Ocampo, AM, Vanegas, JM, Rodríguez, EA, Garcés, CG, Patiño, LA, Ospina, S, Correa, MM (B28) 2011; 106 Didelot, X, Croucher, NJ, Bentley, SD, Harris, SR, Wilson, DJ (B35) 2018; 46 Holden, MTG, Hsu, L-Y, Kurt, K, Weinert, LA, Mather, AE, Harris, SR, Strommenger, B, Layer, F, Witte, W, de Lencastre, H, Skov, R, Westh, H, Zemlicková, H, Coombs, G, Kearns, AM, Hill, RLR, Edgeworth, J, Gould, I, Gant, V, Cooke, J, Edwards, GF, McAdam, PR, Templeton, KE, McCann, A, Zhou, Z, Castillo-Ramírez, S, Feil, EJ, Hudson, LO, Enright, MC, Balloux, F, Aanensen, DM, Spratt, BG, Fitzgerald, JR, Parkhill, J, Achtman, M, Bentley, SD, Nübel, U (B27) 2013; 23 Stamatakis, A (B33) 2014; 30 Brynildsrud, O, Bohlin, J, Scheffer, L, Eldholm, V (B36) 2016; 17 Tsukimori, A, Nakamura, I, Okamura, S, Sato, A, Fukushima, S, Mizuno, Y, Yamaguchi, T, Matsumoto, T (B18) 2014; 14 Park, SH, Park, C, Yoo, J-H, Choi, S-M, Choi, J-H, Shin, H-H, Lee, D-G, Lee, S, Kim, J, Choi, SE, Kwon, Y-M, Shin, W-S (B15) 2009; 30 Joo, E-J, Choi, J-Y, Chung, DR, Song, J-H, Ko, KS (B16) 2016; 54 Thurlow, LR, Joshi, GS, Richardson, AR (B3) 2012; 65 Otto, M (B10) 2010; 64 Moradigaravand, D, Jamrozy, D, Mostowy, R, Anderson, A, Nickerson, EK, Thaipadungpanit, J, Wuthiekanun, V, Limmathurotsakul, D, Tandhavanant, S, Wikraiphat, C, Wongsuvan, G, Teerawattanasook, N, Jutrakul, Y, Srisurat, N, Chaimanee, P, Eoin West, T, Blane, B, Parkhill, J, Chantratita, N, Peacock, SJ (B24) 2017; 8 Seemann, T (B31) 2014; 30 Lee, GC, Dallas, SD, Wang, Y, Olsen, RJ, Lawson, KA, Wilson, J, Frei, CR (B26) 2017; 72 Kobayashi, SD, Malachowa, N, Whitney, AR, Braughton, KR, Gardner, DJ, Long, D, Wardenburg, JB, Schneewind, O, Otto, M, DeLeo, FR (B11) 2011; 204 O'Hara, LM, Calfee, DP, Miller, LG, Pineles, L, Magder, LS, Johnson, JK, Morgan, DJ, Harris, AD (B22) 2019; 69 (B4) 1999; 48 Chen, Y, Yeh, AJ, Cheung, GY, Villaruz, AE, Tan, VY, Joo, H-S, Chatterjee, SS, Yu, Y, Otto, M (B8) 2015; 211 McAdam, PR, Templeton, KE, Edwards, GF, Holden, MTG, Feil, EJ, Aanensen, DM, Bargawi, HJA, Spratt, BG, Bentley, SD, Parkhill, J, Enright, MC, Holmes, A, Girvan, EK, Godfrey, PA, Feldgarden, M, Kearns, AM, Rambaut, A, Robinson, DA, Fitzgerald, JR (B23) 2012; 109 Otto, M (B7) 2013; 303 Park, K-H, Chong, YP, Kim, S-H, Lee, S-O, Choi, S-H, Lee, MS, Jeong, J-Y, Woo, JH, Kim, YS (B13) 2015; 70 Croucher, NJ, Page, AJ, Connor, TR, Delaney, AJ, Keane, JA, Bentley, SD, Parkhill, J, Harris, SR (B32) 2015; 43 Herold, BC, Immergluck, LC, Maranan, MC, Lauderdale, DS, Gaskin, RE, Boyle-Vavra, S, Leitch, CD, Daum, RS (B6) 1998; 279 Potel, C, Rey, S, Otero, S, Rubio, J, Álvarez, M (B20) 2016; 93 Naimi, TS, LeDell, KH, Como-Sabetti, K, Borchardt, SM, Boxrud, DJ, Etienne, J, Johnson, SK, Vandenesch, F, Fridkin, S, O'Boyle, C, Danila, RN, Lynfield, R (B5) 2003; 290 Chung, DR, Baek, JY, Kim, HA, Lim, MH, Kim, SH, Ko, KS, Kang, C-I, Peck, KR, Lee, NY, Song, J-H (B17) 2012; 50 Li, M, Dai, Y, Zhu, Y, Fu, C-L, Tan, VY, Wang, Y, Wang, X, Hong, X, Liu, Q, Li, T, Qin, J, Ma, X, Fang, J, Otto, M (B12) 2016; 6 Lowy, FD (B2) 1998; 339 Jian, Y, Zhao, L, Zhao, N, Lv, H-Y, Liu, Y, He, L, Liu, Q, Li, M (B25) 2021; 10 Choe, D, Szubin, R, Dahesh, S, Cho, S, Nizet, V, Palsson, B, Cho, B-K (B29) 2018; 8 e_1_3_2_26_2 e_1_3_2_27_2 e_1_3_2_28_2 e_1_3_2_29_2 e_1_3_2_20_2 e_1_3_2_21_2 e_1_3_2_22_2 e_1_3_2_23_2 e_1_3_2_24_2 e_1_3_2_25_2 e_1_3_2_9_2 e_1_3_2_15_2 Centers for Disease Control and Prevention (CDC) (e_1_3_2_5_2) 1999; 48 e_1_3_2_8_2 e_1_3_2_16_2 e_1_3_2_37_2 e_1_3_2_7_2 e_1_3_2_17_2 e_1_3_2_6_2 e_1_3_2_18_2 e_1_3_2_19_2 e_1_3_2_30_2 e_1_3_2_32_2 e_1_3_2_10_2 e_1_3_2_31_2 e_1_3_2_11_2 e_1_3_2_34_2 e_1_3_2_4_2 e_1_3_2_12_2 e_1_3_2_33_2 e_1_3_2_3_2 e_1_3_2_13_2 e_1_3_2_36_2 e_1_3_2_2_2 e_1_3_2_14_2 e_1_3_2_35_2 |
References_xml | – volume: 339 start-page: 520 year: 1998 end-page: 532 ident: B2 article-title: Staphylococcus aureus infections publication-title: N Engl J Med doi: 10.1056/NEJM199808203390806 contributor: fullname: Lowy, FD – volume: 204 start-page: 937 year: 2011 end-page: 941 ident: B11 article-title: Comparative analysis of USA300 virulence determinants in a rabbit model of skin and soft tissue infection publication-title: J Infect Dis doi: 10.1093/infdis/jir441 contributor: fullname: DeLeo, FR – volume: 109 start-page: 9107 year: 2012 end-page: 9112 ident: B23 article-title: Molecular tracing of the emergence, adaptation, and transmission of hospital-associated methicillin-resistant Staphylococcus aureus publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1202869109 contributor: fullname: Fitzgerald, JR – volume: 70 year: 2020 ident: B30 article-title: Using SPAdes de novo assembler publication-title: Curr Protoc Bioinformatics doi: 10.1002/cpbi.102 contributor: fullname: Korobeynikov, A – volume: 46 year: 2018 ident: B35 article-title: Bayesian inference of ancestral dates on bacterial phylogenetic trees publication-title: Nucleic Acids Res doi: 10.1093/nar/gky783 contributor: fullname: Wilson, DJ – volume: 72 start-page: 2461 year: 2017 end-page: 2468 ident: B26 article-title: Emerging multidrug resistance in community-associated Staphylococcus aureus involved in skin and soft tissue infections and nasal colonization publication-title: J Antimicrob Chemother doi: 10.1093/jac/dkx200 contributor: fullname: Frei, CR – volume: 8 start-page: 2215 year: 2018 end-page: 2213 ident: B29 article-title: Genome-scale analysis of Methicillin-resistant Staphylococcus aureus USA300 reveals a tradeoff between pathogenesis and drug resistance publication-title: Sci Rep doi: 10.1038/s41598-018-20661-1 contributor: fullname: Cho, B-K – volume: 5 start-page: 183 year: 2010 end-page: 195 ident: B1 article-title: Staphylococcus colonization of the skin and antimicrobial peptides publication-title: Expert Rev Dermatol doi: 10.1586/edm.10.6 contributor: fullname: Otto, M – volume: 60 start-page: 1108 year: 2007 end-page: 1114 ident: B14 article-title: A survey of community-associated methicillin-resistant Staphylococcus aureus in Korea publication-title: J Antimicrob Chemother doi: 10.1093/jac/dkm309 contributor: fullname: Choe, KW – volume: 69 start-page: S171 year: 2019 end-page: S177 ident: B22 article-title: Optimizing contact precautions to curb the spread of antibiotic-resistant bacteria in hospitals: a multicenter cohort study to identify patient characteristics and healthcare personnel interactions associated with transmission of methicillin-resistant Staphylococcus aureus publication-title: Clin Infect Dis doi: 10.1093/cid/ciz621 contributor: fullname: Harris, AD – volume: 50 start-page: 2513 year: 2012 end-page: 2514 ident: B17 article-title: First report of vancomycin-intermediate resistance in sequence type 72 community genotype methicillin-resistant Staphylococcus aureus publication-title: J Clin Microbiol doi: 10.1128/JCM.00590-12 contributor: fullname: Song, J-H – volume: 70 start-page: 1185 year: 2015 end-page: 1192 ident: B13 article-title: Community-associated MRSA strain ST72-SCCmecIV causing bloodstream infections: clinical outcomes and bacterial virulence factors publication-title: J Antimicrob Chemother doi: 10.1093/jac/dku475 contributor: fullname: Kim, YS – volume: 10 start-page: 109 year: 2021 end-page: 154 ident: B25 article-title: Increasing prevalence of hypervirulent ST5 methicillin susceptible Staphylococcus aureus subtype poses a serious clinical threat publication-title: Emerg Microbes Infect doi: 10.1080/22221751.2020.1868950 contributor: fullname: Li, M – volume: 290 start-page: 2976 year: 2003 end-page: 2984 ident: B5 article-title: Comparison of community- and health care-associated methicillin-resistant Staphylococcus aureus infection publication-title: JAMA doi: 10.1001/jama.290.22.2976 contributor: fullname: Lynfield, R – volume: 17 start-page: 238 year: 2016 end-page: 239 ident: B36 article-title: Rapid scoring of genes in microbial pan-genome-wide association studies with Scoary publication-title: Genome Biol doi: 10.1186/s13059-016-1108-8 contributor: fullname: Eldholm, V – volume: 106 start-page: 980 year: 2011 end-page: 985 ident: B28 article-title: Characterisation of virulence genes in methicillin susceptible and resistant Staphylococcus aureus isolates from a paediatric population in a university hospital of Medellin, Colombia publication-title: Mem Inst Oswaldo Cruz doi: 10.1590/s0074-02762011000800013 contributor: fullname: Correa, MM – volume: 14 start-page: 459 year: 2014 ident: B18 article-title: First case report of vancomycin-intermediate sequence type 72 Staphylococcus aureus with nonsusceptibility to daptomycin publication-title: BMC Infect Dis doi: 10.1186/1471-2334-14-459 contributor: fullname: Matsumoto, T – volume: 64 start-page: 143 year: 2010 end-page: 162 ident: B10 article-title: Basis of virulence in community-associated methicillin-resistant Staphylococcus aureus publication-title: Annu Rev Microbiol doi: 10.1146/annurev.micro.112408.134309 contributor: fullname: Otto, M – volume: 303 start-page: 324 year: 2013 end-page: 330 ident: B7 article-title: Community-associated MRSA: what makes them special? publication-title: Int J Med Microbiol doi: 10.1016/j.ijmm.2013.02.007 contributor: fullname: Otto, M – volume: 279 start-page: 593 year: 1998 end-page: 598 ident: B6 article-title: Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk publication-title: JAMA doi: 10.1001/jama.279.8.593 contributor: fullname: Daum, RS – volume: 6 start-page: 27899 year: 2016 ident: B12 article-title: Virulence determinants associated with the Asian community-associated methicillin-resistant Staphylococcus aureus lineage ST59 publication-title: Sci Rep doi: 10.1038/srep27899 contributor: fullname: Otto, M – volume: 359 start-page: 1819 year: 2002 end-page: 1827 ident: B9 article-title: Genome and virulence determinants of high virulence community-acquired MRSA publication-title: Lancet doi: 10.1016/S0140-6736(02)08713-5 contributor: fullname: Hiramatsu, K – volume: 30 start-page: 146 year: 2009 end-page: 155 ident: B15 article-title: Emergence of community-associated methicillin-resistant Staphylococcus aureus strains as a cause of healthcare-associated bloodstream infections in Korea publication-title: Infect Control Hosp Epidemiol doi: 10.1086/593953 contributor: fullname: Shin, W-S – volume: 54 start-page: 445 year: 2016 end-page: 450 ident: B16 article-title: Characteristics of the community-genotype sequence type 72 methicillin-resistant Staphylococcus aureus isolates that underlie their persistence in hospitals publication-title: J Microbiol doi: 10.1007/s12275-016-6157-x contributor: fullname: Ko, KS – volume: 48 start-page: 707 year: 1999 end-page: 710 ident: B4 article-title: Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999 publication-title: MMWR Morbidity and Mortality Wkly Report – volume: 211 start-page: 472 year: 2015 end-page: 480 ident: B8 article-title: Basis of virulence in a Panton-Valentine leukocidin-negative community-associated methicillin-resistant Staphylococcus aureus strain publication-title: J Infect Dis doi: 10.1093/infdis/jiu462 contributor: fullname: Otto, M – volume: 43 year: 2015 ident: B32 article-title: Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins publication-title: Nucleic Acids Res doi: 10.1093/nar/gku1196 contributor: fullname: Harris, SR – volume: 14 start-page: 1635 year: 2021 end-page: 1643 ident: B19 article-title: Molecular epidemiology of methicillin-resistant Staphylococcus aureus in hospitalized patients in eastern Heilongjiang Province, China publication-title: Infect Drug Resist doi: 10.2147/IDR.S307856 contributor: fullname: Li, H – volume: 111 start-page: 6738 year: 2014 end-page: 6743 ident: B21 article-title: Molecular tracing of the emergence, diversification, and transmission of S. aureus sequence type 8 in a New York community publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1401006111 contributor: fullname: Lowy, FD – volume: 37 start-page: 604 year: 2020 end-page: 606 ident: B34 article-title: RASP 4: ancestral state reconstruction tool for multiple genes and characters publication-title: Mol Biol Evol doi: 10.1093/molbev/msz257 contributor: fullname: He, X – volume: 93 start-page: 382 year: 2016 end-page: 385 ident: B20 article-title: Molecular characterization and clonal diversity of meticillin-resistant Staphylococcus aureus isolated from the community in Spain: emergence of clone sequence type 72 publication-title: J Hosp Infect doi: 10.1016/j.jhin.2016.03.012 contributor: fullname: Álvarez, M – volume: 30 start-page: 1312 year: 2014 end-page: 1313 ident: B33 article-title: RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies publication-title: Bioinformatics doi: 10.1093/bioinformatics/btu033 contributor: fullname: Stamatakis, A – volume: 65 start-page: 5 year: 2012 end-page: 22 ident: B3 article-title: Virulence strategies of the dominant USA300 lineage of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) publication-title: FEMS Immunol Med Microbiol doi: 10.1111/j.1574-695X.2012.00937.x contributor: fullname: Richardson, AR – volume: 8 year: 2017 ident: B24 article-title: Evolution of the Staphylococcus argenteus ST2250 clone in Northeastern Thailand is linked with the acquisition of livestock-associated staphylococcal genes publication-title: mBio doi: 10.1128/mBio.00802-17 contributor: fullname: Peacock, SJ – volume: 30 start-page: 2068 year: 2014 end-page: 2069 ident: B31 article-title: Prokka: rapid prokaryotic genome annotation publication-title: Bioinformatics doi: 10.1093/bioinformatics/btu153 contributor: fullname: Seemann, T – volume: 23 start-page: 653 year: 2013 end-page: 664 ident: B27 article-title: A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic publication-title: Genome Res doi: 10.1101/gr.147710.112 contributor: fullname: Nübel, U – ident: e_1_3_2_14_2 doi: 10.1093/jac/dku475 – ident: e_1_3_2_13_2 doi: 10.1038/srep27899 – ident: e_1_3_2_36_2 doi: 10.1093/nar/gky783 – ident: e_1_3_2_8_2 doi: 10.1016/j.ijmm.2013.02.007 – ident: e_1_3_2_18_2 doi: 10.1128/JCM.00590-12 – ident: e_1_3_2_17_2 doi: 10.1007/s12275-016-6157-x – ident: e_1_3_2_34_2 doi: 10.1093/bioinformatics/btu033 – ident: e_1_3_2_29_2 doi: 10.1590/s0074-02762011000800013 – ident: e_1_3_2_24_2 doi: 10.1073/pnas.1202869109 – ident: e_1_3_2_33_2 doi: 10.1093/nar/gku1196 – ident: e_1_3_2_2_2 doi: 10.1586/edm.10.6 – ident: e_1_3_2_4_2 doi: 10.1111/j.1574-695X.2012.00937.x – ident: e_1_3_2_15_2 doi: 10.1093/jac/dkm309 – ident: e_1_3_2_3_2 doi: 10.1056/NEJM199808203390806 – ident: e_1_3_2_9_2 doi: 10.1093/infdis/jiu462 – ident: e_1_3_2_37_2 doi: 10.1186/s13059-016-1108-8 – volume: 48 start-page: 707 year: 1999 ident: e_1_3_2_5_2 article-title: Four pediatric deaths from community-acquired methicillin-resistant Staphylococcus aureus—Minnesota and North Dakota, 1997–1999 publication-title: MMWR Morbidity and Mortality Wkly Report contributor: fullname: Centers for Disease Control and Prevention (CDC) – ident: e_1_3_2_28_2 doi: 10.1101/gr.147710.112 – ident: e_1_3_2_11_2 doi: 10.1146/annurev.micro.112408.134309 – ident: e_1_3_2_32_2 doi: 10.1093/bioinformatics/btu153 – ident: e_1_3_2_30_2 doi: 10.1038/s41598-018-20661-1 – ident: e_1_3_2_6_2 doi: 10.1001/jama.290.22.2976 – ident: e_1_3_2_25_2 doi: 10.1128/mBio.00802-17 – ident: e_1_3_2_26_2 doi: 10.1080/22221751.2020.1868950 – ident: e_1_3_2_35_2 doi: 10.1093/molbev/msz257 – ident: e_1_3_2_20_2 doi: 10.2147/IDR.S307856 – ident: e_1_3_2_12_2 doi: 10.1093/infdis/jir441 – ident: e_1_3_2_7_2 doi: 10.1001/jama.279.8.593 – ident: e_1_3_2_19_2 doi: 10.1186/1471-2334-14-459 – ident: e_1_3_2_22_2 doi: 10.1073/pnas.1401006111 – ident: e_1_3_2_27_2 doi: 10.1093/jac/dkx200 – ident: e_1_3_2_10_2 doi: 10.1016/S0140-6736(02)08713-5 – ident: e_1_3_2_23_2 doi: 10.1093/cid/ciz621 – ident: e_1_3_2_16_2 doi: 10.1086/593953 – ident: e_1_3_2_31_2 doi: 10.1002/cpbi.102 – ident: e_1_3_2_21_2 doi: 10.1016/j.jhin.2016.03.012 |
SSID | ssj0001637129 |
Score | 2.2630088 |
Snippet | Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea,... Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly... Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus isolates is important, as isolates of this lineage have rapidly... Staphylococcus aureus sequence type (ST) 72, the predominant community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) lineage in South Korea,... Understanding the evolution and dissemination of community-genotype ST72 Staphylococcus aureus |
SourceID | doaj pubmedcentral proquest crossref asm2 |
SourceType | Open Website Open Access Repository Aggregation Database |
StartPage | e0098621 |
SubjectTerms | Evolution Research Article |
SummonAdditionalLinks | – databaseName: American Society for Microbiology Open Access dbid: AAUOK link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEBZhQ6GX0ifdvphCoVBwupKt13GbJk1a-oB2ITchayWSQ-wSewv5Mf2vnfHKSU17KMUHgy1boG-k-UbSfGLshY-hrpHXYmxibVFJHoq6TqoIgcS5jIxpOHnu4yd1tKren8iTHabGXJjcgt2e786Hhfyrni3M6_Os4r1HKpiqoPzxXbQhI2Zsd7lcff5wPbuiSo2eLC9j_vVbHIOxDjHxR4Ns_4RrTndK_uZ6Dm-zW5kzwnIL8h22E5u77Mb2FMnLe-zn_rWCN7yLQ54xjGIj8GWbatfBcdNRIN7BWdO3gLwPDn5kuwPfrOlLSmiEt-NODWgT5PyR_rKgH9N8LXzNm6-BQljQApCvIlboFNsQNh34zUXE2zEaNfHY-2x1ePBt_6jIpy4UXmreI90mMXFfIWQm4uXXOq0XIamkla0xugmcB8lj4N5aLa1Ki4TDarJSJh15KB-wWdM28SEDjFC1qUn1DokPF7UJOKRFW1ExFYScs5cEgRtBd0NEIowbwXIDWE7wOXs1ouS-b2U4_rNw90fhNwT6VUGS2x4eoPG53HudDQp9gvFKiVghAbJl8uVaJltxvQh1OWfPR5Nx2D1pzcU3sd10jg4J5AvkoNWc6YktTWqcvmnOTgehbyMrjXzh0T8302N2U9CeG_StQj1hs_5iE58iaerrZ7mH_ALPAhoS priority: 102 providerName: American Society for Microbiology – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3di9QwEA-yIPgifuL6xQiCINTbZJukedTzzjtBEfTg3kKSTfAerpVr9-D-GP_Xm0lT3eKDINKHQpu2oTPJ_CaZ-Q1jL10M3iOuRd_EmKqWPFTeJ1WFQORcjYwpV5779FkdndQfT-XpTqkvigkb6YHHH7dngsLh2DilRKzR9ph1cuuNTKbmehX8yPPJ5Y4zlVdX1FqjJSvbmDgH750XBvA3xKCpKuIGXbj-XMzsUabtn2HNeaTkjuk5vMNuF8wIb8e-3mU3YnuP3RyrSF7dZz_3fzN4w4eY84xhIhuBL2OqXQ_HbU-OeA9n7dAB4j44uCx6B67d0JOU0Ajvp0gN6BKU_JHhqqIX03otfC3B10AuLGgBiFdRVmgUuxC2PbjtRcTTMSo14dgH7OTw4Nv-UVWqLlROaj4g3CYycVejyJqIh9votFmFpJJWxqN3EzgPksfAnTFaGpVWCafVZKRMOvKwfsgWbdfGRwzQQ9WNJ9Y7BD5c-CbglBZNTc1UEHLJXpEIbBk2vc0eiWjsJCybhWUFX7LXk5Tsj5GG4x8b9380fkdC_9WQ6LbzBVRCW5TQ_k0Jl-zFpDIWhyftubg2dtveUpFAvkIMWi-ZnunS7IvzO-3Z90z03chaI154_D-6-ITdEhSOg2ZXqKdsMVxs4zPEU4N_nofONVVWIZY priority: 102 providerName: Directory of Open Access Journals – databaseName: Scholars Portal Open Access Journals dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bi9UwEA7LiuCLrDc83oggCELXkzSX5kFE1113hRVBD-xbSHOSdcFt19Me8fwY_6szaaoW90XpQ6FNU9qZZL5JZr4h5IkLvq4B14JvYkwhJPNFXUdVeI_kXJUMMVWeO36vDhfi3Yk82SJjeav8A7tLXTusJ7VYfdn9_nXzEgb8iyEBpnp-nsm9d5EcUxWYVn6Fi1Kgwh9ntJ-WXFSpWapbxkttCkBCOu9zXtoLTNKuO-cTg5V4_SdgdBpK-YdtOtgh1zOopK8GLbhBtkJzk1wdykxubpEfe78pvunbkBKR6chGQj8MuXgdPWo69NQ7etb0LQVgSPe_ZcWkrlnik5jxSN-MoRy0jTQnmPSbAjvGBV36MUdnU_RxqeYUAC0IE6xm6_26o269CnA6Aq1HoHubLA72P-0dFrksQ-GkZj3gcWQbdwJkWgU43FLH5dxHFbUyNbg_njEvWfDMGaOlUXEeYd6NRsqoA_PlHbLdtE24Syi4sLqqkRYPkBHjdeVhzgtGYDPluZyRpygCO6qFTS4Lr-woLJuEZTmbkWejlOzFwNPxn427vxq_RqH_aoh83OlCuzq1eXhb4xUYjcopxYMAhGTK6MqljEYwPfd1OSOPR5WxMH5xU8Y1oV13FqsIsjmAVDEjeqJLkzdO7zRnnxMTeCWFBkBx718-_j65xjEuB-wvVw_Idr9ah4cArPr6URouPwFV3SWJ priority: 102 providerName: Scholars Portal |
Title | Comparative Genomic Analysis Provides Insights into the Evolution and Genetic Diversity of Community-Genotype Sequence Type 72 Staphylococcus aureus Isolates |
URI | https://journals.asm.org/doi/10.1128/mSystems.00986-21 https://search.proquest.com/docview/2570109294 https://pubmed.ncbi.nlm.nih.gov/PMC8547429 https://doaj.org/article/9c61118a662e461393fa3d5f94170cb3 |
Volume | 6 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1ta9swEBZtx2Bfxl5Z9hI0GAwGTiJZL9bHNEvXbqQL2wL5JmRF2gKLXeJk0B-z_7qTIm81-1YMNtiSbbiT7jnp7jmE3hhnyxJwLfgmSmWME5uVpReZtYGcq-DOx8pzs0txvmAfl3x5hHibCxOD9m25HlQ_N4Nq_SPGVl5t7LCNExvOZ5OCM_Do1PAYHcs8v-Gix4UVkUswYmkHE6bf4SaRfw8CeabIaKgOkzOmQuA9zMSm2dCOVYrk_R3E2Y2XvGGAzh6g-wk54vHhDx-iI1c9QncPtSSvH6Pfk3883viDi9nGuKUcwfNDwl2DL6omuOMNXle7GgP6w9NfSfuwqVahZ0hrxO_beA1ce5yySHbXWXhxWLXFX1MINg6OLJYUA2oFiYFprK3dN9jstw4uF6DaAc0-QYuz6bfJeZZqL2SGS7ID0B0oxQ0DwRUODrOSfjWyXngpVAk-jiXEcuIsMUpJroQfeZhcveLcS0ds_hSdVHXlniEMfqosysB9B_CH0LKwMLE5xUIzYSnvobdBBDoNnkZHv4QWupWbjnLTlPTQu1ZK-upAxnHLxs1_jU-D0P82DKTb8Ua9_a6T6mllBViGwghBHQMYpHJv8hX3ihE5smXeQ69bldEwSMPOi6lcvW90KBVIRoBEWQ_Jji51vth9Atof6b6Ttj-_dc8X6B4NkThgcal4iU522717BVBqV_ZhAC1lH90ZjxefP8H1dHo5_9KPCxNwnrGiHwfXH9IRKQs |
link.rule.ids | 230,315,733,786,790,870,891,2115,2236,24346,27957,27958,31755,33780,53182,53195,53208,53827,53829 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3di9QwEA-yh-iLeH7g-nFGEASh56ZtkuZx78td70PBW7i3kGQT7sRr5dIV7o_xf3Wmm3oWfRDpQ6FNW-jMZH6TzPyGkNfGO2sB10JsolRWcuYya4PInENyror70HWeOz4Rs0X54YyfpaxKrIX5gn15v8ZtEy-7fXw0bFyITv0Iq3eXicl7G5kwRYY15BvY3KAakY3pdPHx8GaFRRQSvFnayvzrszAPw4fygU_qqPsHeHOYLfmb-zm4T-4l3Eina0Fvklu-fkBurztJXj8kP3ZvWLzpe9_VGtOecIR-WpfbRTqvIwbjkV7UbUMB-9H970n3qKmX-CQWNdK9PluDNoGmGpL2OsMX45ot_ZwSsCmGsVTmFDAryAscY-PcKlKzuvJwmoNiI5Z9RBYH-6e7syx1XsgMl6wFyI2E4qYEsVUeDrOUYTlxQQQplIUIxzHmOPOOGaUkVyJMAkytQXEepGeueExGdVP7J4RClCori8x3AH5YbisH05pXJQ4TLudj8gZFoJPpRN1FJXmle2HpTlg6Z2PytpeS_ram4vjPwfGPwTso9F8DkXK7uwAaqJMFa-UE-IXKCJH7EkCQKoIpljyoksmJs8WYvOpVRoOJ4r6LqX2zihobBbIJ4NByTORAlwZfHN6pL847su-KlxIww9N__k0vyZ3Z6fGRPpqfHD4jd3PMwQFfm4vnZNRerfwLAFGt3UrW8hNWSB5s |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwELXQViAuiE-xlA8jISEhpayd2I6PS9ulS6FUgpV6s2zHVntoUjXZSv0x_Fdmsg4lggNCe4i0cRIpb-x5E8-8IeSNDd454LUQm2idFYL5zLkoM-9RnKsUIfad574cyYNV8elEnKSsSqyFSW-w3bHteb-RjzP7ooqpH2H5_jwpee-gEqbMsIZ8C-1ITMjWfL76enjzhUXmCrxZ2sr867WwDsNz-Mgn9dL9I745zpb8zf0s7pN7iTfS-QboB-RWqB-S25tOktePyI_dGxVv-jH0tcZ0EByhx5tyu5Yu6xaD8Zae1V1DgfvR_atke9TWFV6JRY10b8jWoE2kqYaku87wxvjNln5LCdgUw1iqOAXOCniBY2y8X7fUri8DHJZg2MhlH5PVYv_77kGWOi9kVijWAeVGQXFbAGxlgJ-tVKxmPsqopHYQ4XjGvGDBM6u1ElrGWYSlNWohogrM50_IpG7q8JRQiFJV6VD5DsgP4670sKwFXeAw6bmYkrcIgRmAN31UwkszgGV6sAxnU_JuQMlcbKQ4_nNw-8fgDwj6r4Eoud3_AQZo0gw22kvwC6WVkocCSJDOo80rEXXB1My7fEpeDyZjYIrivoutQ7NuDTYKZDPgocWUqJEtjZ44PlOfnfZi36UoFHCGZ__8ml6RO8d7C_N5eXS4Te5yTMEBV8vlczLpLtfhBXCozr1Mk-UnNqkeEQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Comparative+Genomic+Analysis+Provides+Insights+into+the+Evolution+and+Genetic+Diversity+of+Community-Genotype+Sequence+Type+72+Staphylococcus+aureus+Isolates&rft.jtitle=mSystems&rft.au=Zhou%2C+Wangxiao&rft.au=Jin%2C+Ye&rft.au=Zhou%2C+Yanzi&rft.au=Wang%2C+Yuan&rft.date=2021-10-26&rft.issn=2379-5077&rft.eissn=2379-5077&rft.volume=6&rft.issue=5&rft_id=info:doi/10.1128%2FmSystems.00986-21&rft.externalDBID=n%2Fa&rft.externalDocID=10_1128_mSystems_00986_21 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2379-5077&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2379-5077&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2379-5077&client=summon |