Anti-HIV Tigliane Diterpenoids from Wikstroemia scytophylla

• Published in: Journal of natural products (Washington, D.C.) Vol. 83; no. 12; pp. 3584 - 3590
• Main Authors: Otsuki, Kouharu, Zhang, Mi, Yamamoto, Asuka, Tsuji, Minami, Tejima, Miyuko, Bai, Zi-Song, Zhou, Di, Huang, Li, Chen, Chin-Ho, Lee, Kuo-Hsiung, Li, Ning, Li, Wei, Koike, Kazuo
• Format: Journal Article
• Language: English
• Published: WASHINGTON American Chemical Society and American Society of Pharmacognosy 24.12.2020; Amer Chemical Soc
• Subjects: Anti-HIV Agents - chemistry; Anti-HIV Agents - isolation & purification; Anti-HIV Agents - pharmacology; antiretroviral agents; antiretroviral properties; Cell Line; Chemistry, Medicinal; Diterpenes - isolation & purification; Diterpenes - pharmacology; diterpenoids; HIV infections; Humans; Life Sciences & Biomedicine; Pharmacology & Pharmacy; Phorbols - pharmacology; Plant Sciences; Science & Technology; spectral analysis; Spectrum Analysis - methods; Wikstroemia; Wikstroemia - chemistry; DAPHNANE-TYPE DITERPENOIDS; BUDS; STEMS

During a chemical investigation of Wikstroemia scytophylla, three new [wikstrocins A–C (1–3)] and three known tigliane diterpenoids (4–6) were isolated. The structures of the new compounds were elucidated from extensive physiochemical and spectroscopic analysis. The correlations between the ECD Cott...