Phase I, Open-Label, Safety and Pharmacokinetic Study To Assess Bronchopulmonary Disposition of Intravenous Eravacycline in Healthy Men and Women - Connors, Kevin P.; Housman, Seth T.; Pope, J. Samuel; Russomanno, John; Salerno, Edward; Shore, Eric; Redican, Susan; Nicolau, David P. (Antimicrobial agents and chemotherapy, 2014)
Keywords: Adult; Anti-Bacterial Agents; Anti-Bacterial Agents - adverse effects; Anti-Bacterial Agents - blood; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - urine; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Female; Humans; Macrophages, Alveolar - metabolism; Male; Medical sciences; Pharmacology; Pharmacology. Drug treatments; Tetracyclines - adverse effects; Tetracyclines - blood; Tetracyclines - pharmacokinetics; Tetracyclines - urine; Young Adult; Human; Intravenous administration; Healthy subject; Toxicity; Tetracycline derivatives; Sex; Bronchopulmonary; Eravacycline; Antibiotic; Phase I trial; Protein synthesis inhibitor; Safety; Antibacterial agent; Pharmacokinetics