Are Quaternary Ammonium Compounds, the Workhorse Disinfectants, Effective against Severe Acute Respiratory Syndrome-Coronavirus-2?

• Published in: ACS infectious diseases Vol. 6; no. 7; pp. 1553 - 1557
• Main Authors: Schrank, Cassandra L, Minbiole, Kevin P. C, Wuest, William M
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 10.07.2020
• Subjects: Anti-Infective Agents, Local - pharmacology; Benzalkonium Compounds - pharmacology; Betacoronavirus - chemistry; Betacoronavirus - drug effects; Coronavirus Infections - prevention & control; Coronavirus Infections - virology; COVID-19; Disinfectants - pharmacology; Disinfection - methods; Hand Disinfection - methods; Humans; Membrane Lipids; Pandemics - prevention & control; Pneumonia, Viral - prevention & control; Pneumonia, Viral - virology; Sanitation - methods; SARS-CoV-2; Treatment Outcome; Virus Replication - drug effects

A novel virus named Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) emerged from Wuhan, China in late 2019. Since then, the virus has quickly spread worldwide, leading the World Health Organization to declare it as a pandemic; by the end of April 2020, the number of cases exceeded 3 mil...