Concordance between Two Phenotypic Assays and Ultradeep Pyrosequencing for Determining HIV-1 Tropism
Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commerc...
Saved in:
Published in | Antimicrobial Agents and Chemotherapy Vol. 55; no. 6; pp. 2831 - 2836 |
---|---|
Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Washington, DC
American Society for Microbiology
01.06.2011
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Classifications
Services
AAC
Citing Articles
Google Scholar
PubMed
Related Content
Social Bookmarking
CiteULike
Delicious
Digg
Facebook
Google+
Mendeley
Reddit
StumbleUpon
Twitter
current issue
AAC
About
AAC
Subscribers
Authors
Reviewers
Advertisers
Inquiries from the Press
Permissions & Commercial Reprints
ASM Journals Public Access Policy
AAC
RSS Feeds
1752 N Street N.W. • Washington DC 20036
202.737.3600 • 202.942.9355 fax • journals@asmusa.org
Print ISSN:
0066-4804
Online ISSN:
1098-6596
Copyright © 2014
by the
American Society for Microbiology.
For an alternate route to
AAC
.asm.org, visit:
AAC
|
---|---|
AbstractList | There have been few studies on the concordance between phenotypic assays for predicting human immunodeficiency virus type 1 (HIV-1) coreceptor usage. The sensitivity of ultradeep pyrosequencing combined with genotyping tools is similar to that of phenotypic assays for detecting minor CXCR4-using variants. We evaluated the agreement between two phenotypic assays, the Toulouse tropism test (TTT) and the Trofile assay, and ultradeep pyrosequencing for determining the tropism of HIV-1 quasispecies. The concordance between the TTT and Trofile assays was assessed for 181 samples successfully phenotyped by both assays. The TTT was 86% concordant with the standard Trofile assay and 91.7% with its enhanced-sensitivity version. The concordance between phenotypic characterization of HIV-1 tropism and ultradeep pyrosequencing genotypic prediction was further studied in selected samples. The HIV-1 tropism inferred from ultradeep pyrosequencing of 11 samples phenotyped as X4 and dualtropic and 12 phenotyped as R5-tropic agreed closely with the results of phenotyping. However, ultradeep pyrosequencing detected minor CXCR4-using variants in 3 of 12 samples phenotyped as R5-tropic. Ultradeep pyrosequencing also detected minor CXCR4-using variants that had been missed by direct sequencing in 6 of 9 samples phenotyped as X4-tropic but genotyped as R5-tropic by direct sequencing. Ultradeep pyrosequencing was 87% concordant with the Trofile and TTT phenotypic assays and was in the same range of sensitivity (0.4%) than these two phenotypic assays (0.3 to 0.5%) for detecting minor CXCR4-using variants. Ultradeep pyrosequencing provides a new way to improve the performance of genotypic prediction of HIV-1 tropism to match that of the phenotypic assays. ABSTRACT There have been few studies on the concordance between phenotypic assays for predicting human immunodeficiency virus type 1 (HIV-1) coreceptor usage. The sensitivity of ultradeep pyrosequencing combined with genotyping tools is similar to that of phenotypic assays for detecting minor CXCR4-using variants. We evaluated the agreement between two phenotypic assays, the Toulouse tropism test (TTT) and the Trofile assay, and ultradeep pyrosequencing for determining the tropism of HIV-1 quasispecies. The concordance between the TTT and Trofile assays was assessed for 181 samples successfully phenotyped by both assays. The TTT was 86% concordant with the standard Trofile assay and 91.7% with its enhanced-sensitivity version. The concordance between phenotypic characterization of HIV-1 tropism and ultradeep pyrosequencing genotypic prediction was further studied in selected samples. The HIV-1 tropism inferred from ultradeep pyrosequencing of 11 samples phenotyped as X4 and dualtropic and 12 phenotyped as R5-tropic agreed closely with the results of phenotyping. However, ultradeep pyrosequencing detected minor CXCR4-using variants in 3 of 12 samples phenotyped as R5-tropic. Ultradeep pyrosequencing also detected minor CXCR4-using variants that had been missed by direct sequencing in 6 of 9 samples phenotyped as X4-tropic but genotyped as R5-tropic by direct sequencing. Ultradeep pyrosequencing was 87% concordant with the Trofile and TTT phenotypic assays and was in the same range of sensitivity (0.4%) than these two phenotypic assays (0.3 to 0.5%) for detecting minor CXCR4-using variants. Ultradeep pyrosequencing provides a new way to improve the performance of genotypic prediction of HIV-1 tropism to match that of the phenotypic assays. Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology. For an alternate route to AAC .asm.org, visit: AAC |
Author | Jacques Izopet the ANRS AC11 Resistance Study Group Pierre Delobel Bernard Masquelier Stéphanie Raymond Adrien Saliou Martine Dubois Florence Nicot Vincent Calvez |
Author_xml | – sequence: 1 givenname: Adrien surname: SALIOU fullname: SALIOU, Adrien organization: INSERM, UMR1043, 31300,Toulouse, France – sequence: 2 givenname: Pierre surname: DELOBEL fullname: DELOBEL, Pierre organization: INSERM, UMR1043, 31300,Toulouse, France – sequence: 3 givenname: Martine surname: DUBOIS fullname: DUBOIS, Martine organization: INSERM, UMR1043, 31300,Toulouse, France – sequence: 4 givenname: Florence surname: NICOT fullname: NICOT, Florence organization: INSERM, UMR1043, 31300,Toulouse, France – sequence: 5 givenname: Stéphanie surname: RAYMOND fullname: RAYMOND, Stéphanie organization: INSERM, UMR1043, 31300,Toulouse, France – sequence: 6 givenname: Vincent surname: CALVEZ fullname: CALVEZ, Vincent organization: Laboratoire de Virologie, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, UMPC Université Paris 06, INSERM U943, Paris, France – sequence: 7 givenname: Bernard surname: MASQUELIER fullname: MASQUELIER, Bernard organization: Laboratoire de Virologie, CHU de Bordeaux, Bordeaux, France – sequence: 8 givenname: Jacques surname: IZOPET fullname: IZOPET, Jacques organization: INSERM, UMR1043, 31300,Toulouse, France |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24242470$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/21464245$$D View this record in MEDLINE/PubMed https://hal.science/hal-00675722$$DView record in HAL |
BookMark | eNqFktFv0zAQxi00xLrBG88oPCCERIadxI7zghR1QCdVYg8dr9bVubSeEruz01X973HWsgESQn6wzvfzd6fv7oycWGeRkNeMXjCWyU91Pb2glFYsZewZmTBayVTwSpyQCaVCpIWkxSk5C-E2UjFBX5DTjBWiyAo-Ic3UWe18A1ZjssRhh2iTxc4l12u0bthvjE7qEGAfErBNctMNHhrETXK99y7g3RatNnaVtM4nlzig740d49nVj5QlC-82JvQvyfMWuoCvjvc5ufn6ZTGdpfPv366m9TwFnldD2kpkRaGpLJccOGYNFDkFCW0GspECsRGiaAXKRlDWthXKLAeteVuJEijy_Jx8PuhutsseG402dtupjTc9-L1yYNSfGWvWauXuVc4oyyWNAh8OAuu_vs3quRrfooMlL7PsnkX2_bGYd9GGMKjeBI1dBxbdNqiKMcZlxf9PyijJSl7JSH48kDqaGzy2j00wqsZpqzht9TDtGD61C6HP1K3behvt_Rf75ndvHoV_rUIE3h0BCBq61seVMOGJK8ZTjh69PXpkVuud8ahidQWgFedKqEzmLP8J_l3L5g |
CODEN | AACHAX |
CitedBy_id | crossref_primary_10_1016_j_jviromet_2018_08_001 crossref_primary_10_1371_journal_pone_0053603 crossref_primary_10_1517_14740338_2012_640670 crossref_primary_10_1371_journal_pone_0049602 crossref_primary_10_1007_s11908_014_0401_5 crossref_primary_10_1371_journal_pone_0127816 crossref_primary_10_1016_j_jcv_2014_06_013 crossref_primary_10_1002_jmv_23209 crossref_primary_10_1093_jac_dku147 crossref_primary_10_3109_1040841X_2013_867829 crossref_primary_10_1038_srep42215 crossref_primary_10_1002_0471142727_mb0705s96 crossref_primary_10_1128_JCM_02762_14 crossref_primary_10_1038_srep16944 crossref_primary_10_1186_1742_4690_8_56 crossref_primary_10_1128_AAC_02710_13 crossref_primary_10_2217_fvl_13_21 crossref_primary_10_1016_j_dib_2015_12_008 crossref_primary_10_1093_infdis_jir719 crossref_primary_10_1093_jac_dkv026 crossref_primary_10_1097_COH_0b013e328356f6d7 crossref_primary_10_1586_14787210_2013_852469 crossref_primary_10_22207_JPAM_16_2_45 crossref_primary_10_1016_S0213_005X_11_70043_X crossref_primary_10_1016_j_coviro_2011_09_012 crossref_primary_10_1097_QAD_0b013e3283498305 crossref_primary_10_3390_v12070758 crossref_primary_10_1371_journal_pone_0177033 crossref_primary_10_1097_COH_0b013e328356e9da crossref_primary_10_1128_JCM_00798_13 crossref_primary_10_1128_AAC_02159_12 crossref_primary_10_1371_journal_ppat_1006754 crossref_primary_10_1093_jac_dkt290 crossref_primary_10_1016_j_antiviral_2012_11_002 crossref_primary_10_1128_JCM_00092_13 crossref_primary_10_1016_j_virusres_2016_12_008 |
Cites_doi | 10.1016/j.jviromet.2010.06.012 10.1128/JVI.75.1.251-259.2001 10.1038/381667a0 10.1128/AAC.00853-06 10.1128/JCM.01118-06 10.1126/science.1905842 10.1177/135965350701200709 10.1086/648090 10.1016/j.jcv.2009.11.018 10.1038/nbt1371 10.1093/jac/dkq379 10.1126/science.281.5375.363 10.1038/nature03959 10.1038/34571 10.1038/381661a0 10.1126/science.272.5263.872 10.1097/QAD.0b013e32830ebcd4 10.1097/QAD.0b013e32832b4399 10.1056/NEJMoa0803154 10.1093/jac/dkp063 10.1128/AAC.49.11.4721-4732.2005 10.1056/NEJMoa0803152 10.1097/QAI.0b013e3181c8413b 10.1128/JCM.02090-06 10.1128/AAC.00148-10 10.1128/JVI.77.24.13376-13388.2003 10.1128/JCM.02439-08 10.1097/QAD.0b013e3282ef81ea 10.1086/650697 10.1128/jvi.66.5.3183-3187.1992 10.1097/QAD.0b013e32833e6cfb 10.1097/COH.0b013e328322f973 |
ContentType | Journal Article |
Contributor | Montes, B Chidiac, C Maillard, A Michelet, C Weiss, L Poizot-Martin, I Ruffault, A Yazdanpanah, Y Ferré, V Trabaud, M A Cotte, L Izopet, J Raffi, F Lazrek, M Katlama, C Louis, I Neau, D Morand-Joubert, L Nicot, F Cottalorda, J Raymond, S Verdon, R Brun-Vezinet, F Desbois, D Yeni, P Girard, P M Pallier, C Raymond, I Schneider, V Andre, P Tamalet, C Delobel, P Masquelier, B Pialoux, G Reynes, J Massip, P Ravaut, I Durant, J Descamps, D Morlat, P Si-Mohammed, A Macé, M Flandre, F Ragnaud, J M Amiel, C Recordon-Pinson, P Tardy, J C Dupon, M Vittecocq, D Dussaix, E Soulié, C Marcelin, A G Fleury, H Charpentier, C Segondy, M Calvez, V Marchou, B Vabret, A Delfraissy, J F Prazuck, T |
Contributor_xml | – sequence: 1 givenname: P surname: Recordon-Pinson fullname: Recordon-Pinson, P – sequence: 2 givenname: H surname: Fleury fullname: Fleury, H – sequence: 3 givenname: B surname: Masquelier fullname: Masquelier, B – sequence: 4 givenname: A surname: Vabret fullname: Vabret, A – sequence: 5 givenname: C surname: Pallier fullname: Pallier, C – sequence: 6 givenname: M surname: Lazrek fullname: Lazrek, M – sequence: 7 givenname: P surname: Andre fullname: Andre, P – sequence: 8 givenname: J C surname: Tardy fullname: Tardy, J C – sequence: 9 givenname: M A surname: Trabaud fullname: Trabaud, M A – sequence: 10 givenname: C surname: Tamalet fullname: Tamalet, C – sequence: 11 givenname: B surname: Montes fullname: Montes, B – sequence: 12 givenname: M surname: Segondy fullname: Segondy, M – sequence: 13 givenname: V surname: Ferré fullname: Ferré, V – sequence: 14 givenname: J surname: Cottalorda fullname: Cottalorda, J – sequence: 15 givenname: M surname: Macé fullname: Macé, M – sequence: 16 givenname: D surname: Descamps fullname: Descamps, D – sequence: 17 givenname: F surname: Brun-Vezinet fullname: Brun-Vezinet, F – sequence: 18 givenname: A surname: Si-Mohammed fullname: Si-Mohammed, A – sequence: 19 givenname: C surname: Charpentier fullname: Charpentier, C – sequence: 20 givenname: D surname: Desbois fullname: Desbois, D – sequence: 21 givenname: E surname: Dussaix fullname: Dussaix, E – sequence: 22 givenname: A G surname: Marcelin fullname: Marcelin, A G – sequence: 23 givenname: C surname: Soulié fullname: Soulié, C – sequence: 24 givenname: V surname: Calvez fullname: Calvez, V – sequence: 25 givenname: F surname: Flandre fullname: Flandre, F – sequence: 26 givenname: L surname: Morand-Joubert fullname: Morand-Joubert, L – sequence: 27 givenname: C surname: Amiel fullname: Amiel, C – sequence: 28 givenname: V surname: Schneider fullname: Schneider, V – sequence: 29 givenname: A surname: Maillard fullname: Maillard, A – sequence: 30 givenname: A surname: Ruffault fullname: Ruffault, A – sequence: 31 givenname: J surname: Izopet fullname: Izopet, J – sequence: 32 givenname: F surname: Nicot fullname: Nicot, F – sequence: 33 givenname: P surname: Delobel fullname: Delobel, P – sequence: 34 givenname: S surname: Raymond fullname: Raymond, S – sequence: 35 givenname: P surname: Morlat fullname: Morlat, P – sequence: 36 givenname: I surname: Louis fullname: Louis, I – sequence: 37 givenname: J M surname: Ragnaud fullname: Ragnaud, J M – sequence: 38 givenname: D surname: Neau fullname: Neau, D – sequence: 39 givenname: M surname: Dupon fullname: Dupon, M – sequence: 40 givenname: I surname: Raymond fullname: Raymond, I – sequence: 41 givenname: R surname: Verdon fullname: Verdon, R – sequence: 42 givenname: J F surname: Delfraissy fullname: Delfraissy, J F – sequence: 43 givenname: Y surname: Yazdanpanah fullname: Yazdanpanah, Y – sequence: 44 givenname: C surname: Chidiac fullname: Chidiac, C – sequence: 45 givenname: L surname: Cotte fullname: Cotte, L – sequence: 46 givenname: I surname: Poizot-Martin fullname: Poizot-Martin, I – sequence: 47 givenname: I surname: Ravaut fullname: Ravaut, I – sequence: 48 givenname: J surname: Reynes fullname: Reynes, J – sequence: 49 givenname: F surname: Raffi fullname: Raffi, F – sequence: 50 givenname: J surname: Durant fullname: Durant, J – sequence: 51 givenname: T surname: Prazuck fullname: Prazuck, T – sequence: 52 givenname: P surname: Yeni fullname: Yeni, P – sequence: 53 givenname: L surname: Weiss fullname: Weiss, L – sequence: 54 givenname: D surname: Vittecocq fullname: Vittecocq, D – sequence: 55 givenname: C surname: Katlama fullname: Katlama, C – sequence: 56 givenname: P M surname: Girard fullname: Girard, P M – sequence: 57 givenname: G surname: Pialoux fullname: Pialoux, G – sequence: 58 givenname: C surname: Michelet fullname: Michelet, C – sequence: 59 givenname: B surname: Marchou fullname: Marchou, B – sequence: 60 givenname: P surname: Massip fullname: Massip, P |
Copyright | 2015 INIST-CNRS Copyright © 2011, American Society for Microbiology Distributed under a Creative Commons Attribution 4.0 International License Copyright © 2011, American Society for Microbiology 2011 American Society for Microbiology |
Copyright_xml | – notice: 2015 INIST-CNRS – notice: Copyright © 2011, American Society for Microbiology – notice: Distributed under a Creative Commons Attribution 4.0 International License – notice: Copyright © 2011, American Society for Microbiology 2011 American Society for Microbiology |
CorporateAuthor | ANRS AC11 Resistance Study Group the ANRS AC11 Resistance Study Group |
CorporateAuthor_xml | – name: ANRS AC11 Resistance Study Group – name: the ANRS AC11 Resistance Study Group |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 7T7 7U9 8FD C1K FR3 H94 P64 1XC 5PM |
DOI | 10.1128/AAC.00091-11 |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic Industrial and Applied Microbiology Abstracts (Microbiology A) Virology and AIDS Abstracts Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database AIDS and Cancer Research Abstracts Biotechnology and BioEngineering Abstracts Hyper Article en Ligne (HAL) PubMed Central (Full Participant titles) |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic Virology and AIDS Abstracts Technology Research Database AIDS and Cancer Research Abstracts Engineering Research Database Industrial and Applied Microbiology Abstracts (Microbiology A) Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management |
DatabaseTitleList | CrossRef MEDLINE Virology and AIDS Abstracts |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Pharmacy, Therapeutics, & Pharmacology Biology |
EISSN | 1098-6596 |
EndPage | 2836 |
ExternalDocumentID | oai_HAL_hal_00675722v1 10_1128_AAC_00091_11 0091-11 21464245 24242470 aac_55_6_2831 |
Genre | Research Support, Non-U.S. Gov't Journal Article |
GroupedDBID | --- .55 .GJ 08R 0R~ 23M 2WC 39C 3O- 4.4 53G 5GY 5RE 5VS 6J9 AAPBV AAUGY ACGFO ADBBV AENEX AFMIJ AGNAY AI. ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BTFSW C1A CS3 DIK E3Z EBS EJD F5P FRP GX1 H13 HH5 HYE HZ~ H~9 IQODW J5H K-O KQ8 L7B LSO MVM NEJ O9- OK1 P2P RHF RHI RNS RPM RSF TR2 UHB VH1 W2D W8F WH7 WHG WOQ X7M X7N XOL Y6R ZA5 ZGI ZXP ~A~ AGVNZ CGR CUY CVF ECM EIF NPM - 0R 55 A ABFLS ADACO BXI HZ AAYXX CITATION 7X8 7T7 7U9 8FD C1K FR3 H94 P64 1XC 5PM |
ID | FETCH-LOGICAL-a539t-f8e144c087b5a5e2da430a8af2a8d86eed664f6e8d601ff9e823acc5f967a0e53 |
IEDL.DBID | RPM |
ISSN | 0066-4804 |
IngestDate | Tue Sep 17 21:20:18 EDT 2024 Tue Oct 15 15:29:50 EDT 2024 Fri Aug 16 04:19:49 EDT 2024 Wed Jul 24 13:56:37 EDT 2024 Thu Sep 12 17:51:17 EDT 2024 Tue Dec 28 13:59:10 EST 2021 Sat Sep 28 07:58:38 EDT 2024 Sun Oct 22 16:05:38 EDT 2023 Wed May 18 15:26:49 EDT 2016 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 6 |
Keywords | Tropism Immunopathology HIV-1 virus Retroviridae AIDS Immune deficiency Lentivirus Infection Virus Phenotype Viral disease Concordance Human immunodeficiency virus |
Language | English |
License | CC BY 4.0 Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-a539t-f8e144c087b5a5e2da430a8af2a8d86eed664f6e8d601ff9e823acc5f967a0e53 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1 PMCID: PMC3101380 |
ORCID | 0000-0002-3780-5844 0000-0002-8462-3234 0000-0002-3674-1965 |
OpenAccessLink | https://europepmc.org/articles/pmc3101380?pdf=render |
PMID | 21464245 |
PQID | 875717598 |
PQPubID | 23479 |
PageCount | 6 |
ParticipantIDs | crossref_primary_10_1128_AAC_00091_11 proquest_miscellaneous_911158951 pubmedcentral_primary_oai_pubmedcentral_nih_gov_3101380 pubmed_primary_21464245 hal_primary_oai_HAL_hal_00675722v1 proquest_miscellaneous_875717598 asm2_journals_10_1128_AAC_00091_11 highwire_asm_aac_55_6_2831 pascalfrancis_primary_24242470 |
PublicationCentury | 2000 |
PublicationDate | 2011-06-01 |
PublicationDateYYYYMMDD | 2011-06-01 |
PublicationDate_xml | – month: 06 year: 2011 text: 2011-06-01 day: 01 |
PublicationDecade | 2010 |
PublicationPlace | Washington, DC |
PublicationPlace_xml | – name: Washington, DC – name: United States – name: 1752 N St., N.W., Washington, DC |
PublicationTitle | Antimicrobial Agents and Chemotherapy |
PublicationTitleAbbrev | Antimicrob Agents Chemother |
PublicationTitleAlternate | Antimicrob Agents Chemother |
PublicationYear | 2011 |
Publisher | American Society for Microbiology |
Publisher_xml | – name: American Society for Microbiology |
References | 20599562 - J Virol Methods. 2010 Oct;169(1):39-46 8629022 - Science. 1996 May 10;272(5263):872-7 9705713 - Science. 1998 Jul 17;281(5375):363, 365 20736814 - AIDS. 2010 Oct 23;24(16):2517-25 9440686 - Nature. 1998 Jan 15;391(6664):240 18066037 - Nat Biotechnol. 2007 Dec;25(12):1407-10 19996764 - J Acquir Immune Defic Syndr. 2010 Feb;53(2):167-75 18753930 - AIDS. 2008 Sep 12;22(14):F11-6 19439544 - J Clin Microbiol. 2009 Jul;47(7):2292-4 19339953 - Curr Opin HIV AIDS. 2009 Mar;4(2):136-42 16056220 - Nature. 2005 Sep 15;437(7057):376-80 18832245 - N Engl J Med. 2008 Oct 2;359(14):1442-55 16251317 - Antimicrob Agents Chemother. 2005 Nov;49(11):4721-32 18018768 - Antivir Ther. 2007;12(7):1097-106 11119595 - J Virol. 2001 Jan;75(1):251-9 19874179 - J Infect Dis. 2009 Dec 1;200(11):1724-8 1560543 - J Virol. 1992 May;66(5):3183-7 19424056 - AIDS. 2009 Jun 19;23(10):1209-18 14645592 - J Virol. 2003 Dec;77(24):13376-88 18832244 - N Engl J Med. 2008 Oct 2;359(14):1429-41 8649511 - Nature. 1996 Jun 20;381(6584):661-6 20947622 - J Antimicrob Chemother. 2010 Dec;65(12):2493-501 17329448 - J Clin Microbiol. 2007 May;45(5):1572-80 17721088 - AIDS. 2007 Sep 12;21(14):F17-24 8649512 - Nature. 1996 Jun 20;381(6584):667-73 17122004 - J Clin Microbiol. 2007 Feb;45(2):279-84 19261623 - J Antimicrob Chemother. 2009 May;63(5):1006-10 20530226 - Antimicrob Agents Chemother. 2010 Aug;54(8):3335-40 20151839 - J Infect Dis. 2010 Mar 15;201(6):803-13 1905842 - Science. 1991 Jul 5;253(5015):71-4 17116663 - Antimicrob Agents Chemother. 2007 Feb;51(2):566-75 20015684 - J Clin Virol. 2010 Feb;47(2):126-30 B27 McGovern, R. A. (B20) 2010; 24 Raymond, S. (B22) 2010; 47 Skrabal, K. (B31) 2007; 45 Lengauer, T., Sander, O., Sierra, S., Thielen, A., Kaiser, R. (B15) 2007; 25 Raymond, S. (B23) 2009; 47 Archer, J. (B1) 2009; 23 Cooper, D. A. (B3) 2010; 201 Lin, N. H. (B16) 2010; 169 Su, Z. (B32) 2009; 200 Feng, Y., Broder, C. C., Kennedy, P. E., Berger, E. A. (B9) 1996; 272 Gonzalez, N. (B11) 2010; 65 Rose, J. D., Rhea, A. M., Weber, J., Quinones-Mateu, M. E. (B29) 2009; 4 Raymond, S. (B25) 2010; 53 Sing, T. (B30) 2007; 12 Low, A. J. (B17) 2007; 21 Dorr, P. (B6) 2005; 49 Dragic, T. (B7) 1996; 381 Margulies, M. (B18) 2005; 437 Fouchier, R. A. (B10) 1992; 66 B19 Berger, E. A. (B2) 1998; 391 Deng, H. (B5) 1996; 381 Whitcomb, J. M. (B34) 2007; 51 Ronaghi, M., Uhlen, M., Nyren, P. (B28) 1998; 281 Hwang, S. S., Boyle, T. J., Lyerly, H. K., Cullen, B. R. (B13) 1991; 253 Jensen, M. A. (B14) 2003; 77 Trouplin, V. (B33) 2001; 75 Delobel, P. (B4) 2007; 45 Recordon-Pinson, P. (B26) 2010; 54 Poveda, E. (B21) 2009; 63 Fatkenheuer, G. (B8) 2008; 359 Gulick, R. M. (B12) 2008; 359 Raymond, S. (B24) 2008; 22 e_1_3_3_17_2 Reeves J. D. (e_1_3_3_28_2) 2007 e_1_3_3_16_2 e_1_3_3_19_2 e_1_3_3_18_2 e_1_3_3_13_2 e_1_3_3_12_2 e_1_3_3_15_2 e_1_3_3_34_2 e_1_3_3_14_2 e_1_3_3_35_2 e_1_3_3_32_2 e_1_3_3_33_2 e_1_3_3_11_2 e_1_3_3_30_2 e_1_3_3_10_2 McGovern R. (e_1_3_3_20_2) 2010 e_1_3_3_6_2 Sing T. (e_1_3_3_31_2) 2007; 12 e_1_3_3_5_2 e_1_3_3_8_2 e_1_3_3_7_2 e_1_3_3_9_2 e_1_3_3_27_2 e_1_3_3_29_2 e_1_3_3_24_2 e_1_3_3_23_2 e_1_3_3_26_2 e_1_3_3_25_2 e_1_3_3_2_2 e_1_3_3_4_2 e_1_3_3_22_2 e_1_3_3_3_2 e_1_3_3_21_2 |
References_xml | – volume: 47 start-page: 126 year: 2010 end-page: 130 ident: B22 article-title: Development and performance of a new recombinant virus phenotypic entry assay to determine HIV-1 coreceptor usage publication-title: J. Clin. Virol contributor: fullname: Raymond, S. – ident: B19 article-title: McGovern R. . 2010 . Population-based sequencing of the V3-loop is comparable to the enhanced sensitivity Trofile assay in predicting virologic response to maraviroc of treatment-naive patients in the MERIT Trial . 17th Conference on Retroviruses and Opportunistic Infections , San Francisco, CA . – volume: 63 start-page: 1006 year: 2009 end-page: 1010 ident: B21 article-title: Design and validation of new genotypic tools for easy and reliable estimation of HIV tropism before using CCR5 antagonists publication-title: J. Antimicrob. Chemother contributor: fullname: Poveda, E. – volume: 272 start-page: 872 year: 1996 end-page: 877 ident: B9 article-title: HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor publication-title: Science contributor: fullname: Berger, E. A. – volume: 169 start-page: 39 year: 2010 end-page: 46 ident: B16 article-title: The design and validation of a novel phenotypic assay to determine HIV-1 coreceptor usage of clinical isolates publication-title: J. Virol. Methods contributor: fullname: Lin, N. H. – ident: B27 article-title: Reeves J. D. . 2007 . Enhancements to the Trofile HIV coreceptor tropism assay enable reliable detection of CXCR4-using subpopulations at <1% . 47th Annu. Intersci. Conf. Antimicrob. Agents Chemother . – volume: 22 start-page: F11 year: 2008 end-page: F16 ident: B24 article-title: Correlation between genotypic predictions based on V3 sequences and phenotypic determination of HIV-1 tropism publication-title: AIDS contributor: fullname: Raymond, S. – volume: 201 start-page: 803 year: 2010 end-page: 813 ident: B3 article-title: Maraviroc versus efavirenz, both in combination with zidovudine-lamivudine, for the treatment of antiretroviral-naive subjects with CCR5-tropic HIV-1 infection publication-title: J. Infect. Dis contributor: fullname: Cooper, D. A. – volume: 24 start-page: 2517 year: 2010 end-page: 2525 ident: B20 article-title: Population-based V3 genotypic tropism assay: a retrospective analysis using screening samples from the A4001029 and MOTIVATE studies publication-title: AIDS contributor: fullname: McGovern, R. A. – volume: 54 start-page: 3335 year: 2010 end-page: 3340 ident: B26 article-title: Evaluation of the genotypic prediction of HIV-1 coreceptor use versus a phenotypic assay and correlation with the virological response to maraviroc: the ANRS GenoTropism study publication-title: Antimicrob. Agents Chemother contributor: fullname: Recordon-Pinson, P. – volume: 391 start-page: 240 year: 1998 ident: B2 article-title: A new classification for HIV-1 publication-title: Nature contributor: fullname: Berger, E. A. – volume: 253 start-page: 71 year: 1991 end-page: 74 ident: B13 article-title: Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1 publication-title: Science contributor: fullname: Cullen, B. R. – volume: 65 start-page: 2493 year: 2010 end-page: 2501 ident: B11 article-title: A sensitive phenotypic assay for the determination of human immunodeficiency virus type 1 tropism publication-title: J. Antimicrob. Chemother contributor: fullname: Gonzalez, N. – volume: 21 start-page: F17 year: 2007 end-page: F24 ident: B17 article-title: Current V3 genotyping algorithms are inadequate for predicting X4 coreceptor usage in clinical isolates publication-title: AIDS contributor: fullname: Low, A. J. – volume: 49 start-page: 4721 year: 2005 end-page: 4732 ident: B6 article-title: Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity publication-title: Antimicrob. Agents Chemother contributor: fullname: Dorr, P. – volume: 4 start-page: 136 year: 2009 end-page: 142 ident: B29 article-title: Current tests to evaluate HIV-1 coreceptor tropism publication-title: Curr. Opin. HIV AIDS contributor: fullname: Quinones-Mateu, M. E. – volume: 437 start-page: 376 year: 2005 end-page: 380 ident: B18 article-title: Genome sequencing in microfabricated high-density picolitre reactors publication-title: Nature contributor: fullname: Margulies, M. – volume: 51 start-page: 566 year: 2007 end-page: 575 ident: B34 article-title: Development and characterization of a novel single-cycle recombinant-virus assay to determine human immunodeficiency virus type 1 coreceptor tropism publication-title: Antimicrob. Agents Chemother contributor: fullname: Whitcomb, J. M. – volume: 77 start-page: 13376 year: 2003 end-page: 13388 ident: B14 article-title: Improved coreceptor usage prediction and genotypic monitoring of R5-to-X4 transition by motif analysis of human immunodeficiency virus type 1 env V3 loop sequences publication-title: J. Virol contributor: fullname: Jensen, M. A. – volume: 381 start-page: 661 year: 1996 end-page: 666 ident: B5 article-title: Identification of a major coreceptor for primary isolates of HIV-1 publication-title: Nature contributor: fullname: Deng, H. – volume: 66 start-page: 3183 year: 1992 end-page: 3187 ident: B10 article-title: Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule publication-title: J. Virol contributor: fullname: Fouchier, R. A. – volume: 381 start-page: 667 year: 1996 end-page: 673 ident: B7 article-title: HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5 publication-title: Nature contributor: fullname: Dragic, T. – volume: 23 start-page: 1209 year: 2009 end-page: 1218 ident: B1 article-title: Detection of low-frequency pretherapy chemokine (CXC motif) receptor 4 (CXCR4)-using HIV-1 with ultra-deep pyrosequencing publication-title: AIDS contributor: fullname: Archer, J. – volume: 359 start-page: 1429 year: 2008 end-page: 1441 ident: B12 article-title: Maraviroc for previously treated patients with R5 HIV-1 infection publication-title: N. Engl. J. Med contributor: fullname: Gulick, R. M. – volume: 281 start-page: 363 year: 1998 end-page: 365 ident: B28 article-title: A sequencing method based on real-time pyrophosphate publication-title: Science contributor: fullname: Nyren, P. – volume: 75 start-page: 251 year: 2001 end-page: 259 ident: B33 article-title: Determination of coreceptor usage of human immunodeficiency virus type 1 from patient plasma samples by using a recombinant phenotypic assay publication-title: J. Virol contributor: fullname: Trouplin, V. – volume: 12 start-page: 1097 year: 2007 end-page: 1106 ident: B30 article-title: Predicting HIV coreceptor usage on the basis of genetic and clinical covariates publication-title: Antivir. Ther contributor: fullname: Sing, T. – volume: 200 start-page: 1724 year: 2009 end-page: 1728 ident: B32 article-title: Response to vicriviroc in treatment-experienced subjects, as determined by an enhanced-sensitivity coreceptor tropism assay: reanalysis of AIDS clinical trials group A5211 publication-title: J. Infect. Dis contributor: fullname: Su, Z. – volume: 47 start-page: 2292 year: 2009 end-page: 2294 ident: B23 article-title: Genotypic prediction of human immunodeficiency virus type 1 CRF02-AG tropism publication-title: J. Clin. Microbiol contributor: fullname: Raymond, S. – volume: 53 start-page: 167 year: 2010 end-page: 175 ident: B25 article-title: Prediction of HIV type 1 subtype C tropism by genotypic algorithms built from subtype B viruses publication-title: J. Acquir. Immune Defic. Syndr contributor: fullname: Raymond, S. – volume: 45 start-page: 279 year: 2007 end-page: 284 ident: B31 article-title: Determining human immunodeficiency virus coreceptor use in a clinical setting: degree of correlation between two phenotypic assays and a bioinformatic model publication-title: J. Clin. Microbiol contributor: fullname: Skrabal, K. – volume: 25 start-page: 1407 year: 2007 end-page: 1410 ident: B15 article-title: Bioinformatics prediction of HIV coreceptor usage publication-title: Nat. Biotechnol contributor: fullname: Kaiser, R. – volume: 45 start-page: 1572 year: 2007 end-page: 1580 ident: B4 article-title: Population-based sequencing of the V3 region of env for predicting the coreceptor usage of human immunodeficiency virus type 1 quasispecies publication-title: J. Clin. Microbiol contributor: fullname: Delobel, P. – volume: 359 start-page: 1442 year: 2008 end-page: 1455 ident: B8 article-title: Subgroup analyses of maraviroc in previously treated R5 HIV-1 infection publication-title: N. Engl. J. Med contributor: fullname: Fatkenheuer, G. – ident: e_1_3_3_17_2 doi: 10.1016/j.jviromet.2010.06.012 – ident: e_1_3_3_34_2 doi: 10.1128/JVI.75.1.251-259.2001 – ident: e_1_3_3_8_2 doi: 10.1038/381667a0 – ident: e_1_3_3_35_2 doi: 10.1128/AAC.00853-06 – ident: e_1_3_3_32_2 doi: 10.1128/JCM.01118-06 – ident: e_1_3_3_14_2 doi: 10.1126/science.1905842 – volume: 12 start-page: 1097 year: 2007 ident: e_1_3_3_31_2 article-title: Predicting HIV coreceptor usage on the basis of genetic and clinical covariates publication-title: Antivir. Ther doi: 10.1177/135965350701200709 contributor: fullname: Sing T. – ident: e_1_3_3_33_2 doi: 10.1086/648090 – ident: e_1_3_3_23_2 doi: 10.1016/j.jcv.2009.11.018 – ident: e_1_3_3_16_2 doi: 10.1038/nbt1371 – ident: e_1_3_3_12_2 doi: 10.1093/jac/dkq379 – ident: e_1_3_3_29_2 doi: 10.1126/science.281.5375.363 – ident: e_1_3_3_19_2 doi: 10.1038/nature03959 – ident: e_1_3_3_3_2 doi: 10.1038/34571 – ident: e_1_3_3_6_2 doi: 10.1038/381661a0 – ident: e_1_3_3_10_2 doi: 10.1126/science.272.5263.872 – ident: e_1_3_3_25_2 doi: 10.1097/QAD.0b013e32830ebcd4 – ident: e_1_3_3_2_2 doi: 10.1097/QAD.0b013e32832b4399 – volume-title: 17th Conference on Retroviruses and Opportunistic Infections year: 2010 ident: e_1_3_3_20_2 contributor: fullname: McGovern R. – ident: e_1_3_3_9_2 doi: 10.1056/NEJMoa0803154 – ident: e_1_3_3_22_2 doi: 10.1093/jac/dkp063 – ident: e_1_3_3_7_2 doi: 10.1128/AAC.49.11.4721-4732.2005 – ident: e_1_3_3_13_2 doi: 10.1056/NEJMoa0803152 – ident: e_1_3_3_26_2 doi: 10.1097/QAI.0b013e3181c8413b – volume-title: 47th Annu. Intersci. Conf. Antimicrob. Agents Chemother year: 2007 ident: e_1_3_3_28_2 contributor: fullname: Reeves J. D. – ident: e_1_3_3_5_2 doi: 10.1128/JCM.02090-06 – ident: e_1_3_3_27_2 doi: 10.1128/AAC.00148-10 – ident: e_1_3_3_15_2 doi: 10.1128/JVI.77.24.13376-13388.2003 – ident: e_1_3_3_24_2 doi: 10.1128/JCM.02439-08 – ident: e_1_3_3_18_2 doi: 10.1097/QAD.0b013e3282ef81ea – ident: e_1_3_3_4_2 doi: 10.1086/650697 – ident: e_1_3_3_11_2 doi: 10.1128/jvi.66.5.3183-3187.1992 – ident: e_1_3_3_21_2 doi: 10.1097/QAD.0b013e32833e6cfb – ident: e_1_3_3_30_2 doi: 10.1097/COH.0b013e328322f973 |
SSID | ssj0006590 |
Score | 2.2985876 |
Snippet | Classifications
Services
AAC
Citing Articles
Google Scholar
PubMed
Related Content
Social Bookmarking
CiteULike
Delicious
Digg
Facebook
Google+
Mendeley
Reddit... There have been few studies on the concordance between phenotypic assays for predicting human immunodeficiency virus type 1 (HIV-1) coreceptor usage. The... ABSTRACT There have been few studies on the concordance between phenotypic assays for predicting human immunodeficiency virus type 1 (HIV-1) coreceptor usage.... |
SourceID | pubmedcentral hal proquest crossref asm2 pubmed pascalfrancis highwire |
SourceType | Open Access Repository Aggregation Database Index Database Publisher |
StartPage | 2831 |
SubjectTerms | Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences CCR5 Receptor Antagonists Genotyping HIV-1 HIV-1 - genetics HIV-1 - physiology Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Life Sciences Medical sciences Microbiology and Parasitology Middle Aged Pharmacology. Drug treatments Phenotype Phenotyping Receptors, CCR5 Receptors, CXCR4 Receptors, CXCR4 - physiology Sequence Analysis, DNA Tropism Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viral Tropism |
Title | Concordance between Two Phenotypic Assays and Ultradeep Pyrosequencing for Determining HIV-1 Tropism |
URI | http://aac.asm.org/content/55/6/2831.abstract https://www.ncbi.nlm.nih.gov/pubmed/21464245 https://journals.asm.org/doi/10.1128/AAC.00091-11 https://search.proquest.com/docview/875717598 https://search.proquest.com/docview/911158951 https://hal.science/hal-00675722 https://pubmed.ncbi.nlm.nih.gov/PMC3101380 |
Volume | 55 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwELfWSSBeEJSvblBZE-xpWZP4I85jVZgKoqgPLdqb5TiOVmlNqqUD5b_fXT5aitgLj0kuTpy7y53t3_1MyEdpY0haBfMcs77HRcS9BAt8eBAgPxwLpMVq5NkPOV3yb9fi-oiIrhamBu3bZHWZ364v89VNja3crO2ow4mN5rMJpCQBU_6oR3oRY90Qvf39StFMrEAs9bjyeYd2D9VoPJ4gX2EceEFQswBziQt_8Dc25To8iEy9G8RF7jiDETJpSvhqWbPdxb_y0b9hlX_EqasX5HmbYNJx05GX5MjlffKk2XKy6pOns3YxvU_O5w1tdXVBF_sqrPKCntP5ntC6ekXSSYFslykaCG2BXXTxuwAxlxfbarOyFNRsqpKaPKXLW3iv1LkNnVfQ0warDRGSQn5MP7fwGzyefv3pBXRxV2xW5fo1WV59WUymXrs7g2cEi7dephwMxqyvokQY4cLUcOYbZbLQqFRJiL1S8kw6lcKYL8tip0JmrBVZLCPjO8HekOO8yN07QpWKM65k4oRMeZbGCfLyqdCyVIApSTUgZ6gg3bpXqeuRS6g0KFTXCoXDAfnUqU9vGqaOR-TOQLc7EaTXno6_azyHoVtEYfgLhE461Wt4tDbGaiG01JCNwcXhgTHs2sJSm5BH_oDQzjo0eCsuwZjcFfelxu0DIGGL1eMiGH2EgsR3QN429rRvvzXYAYkOLO2gM4dXwIVqzvDWZU7--85T8qyZTscJqPfkeHt37z5APrZNhhgNxbD2wgc5iDFn |
link.rule.ids | 230,315,733,786,790,891,27955,27956,53825,53827 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3Pb9MwGLW2IWAXfpTBOmBYE-y0tIljO86xKkwdtFMP7bSb5TiOVrEm1dKCwl_P5_xo6cQOcEz9NZXdZ3_P9vMzQh-5DoG0Mt8xvnYdygLqRPaAD_U86w_ne1zb08ijSz6Y0q_X7HoHseYsTCna19Gsk97OO-nsptRWLua62-jEuuNRHyiJ5wu3u4seQX8lrJmk1wMwZ9XSCmRThwqXNnp3Irq9Xt86Foae43mlDzDldusPxmOVz8lWbtq9scrItWuwFU2qHNotqS68-BsjvS-s_CNTnT9HV00dK4HK985qGXX0r3v2j__cCC_Qs5q74l5V_BLtmLSFHle3WRYt9GRU79O30Om4csQuzvBkc8ArP8OneLzxyi5eobifWSPN2GIP15oxPPmZQZhJs2WxmGkMCFJFjlUa4-ktVDg2ZoHHBTRhJQOH5IuBeuPPtbLHPg8urhwPT-6yxSyfH6Dp-ZdJf-DUFz84ivnh0kmEgXmedkUQMcUMiRX1XSVUQpSIBYe0zjlNuBExTCeTJDSC-EprloQ8UK5h_mu0l2apOURYiDChgkeG8ZgmcRhZyz9BtB8zQCkXbXRi_3lZ99xclpMiIiQgRZZIgcc2-tTgQi4qE5AH4k4ANOsQ69w96A2l_cyyAhYQ8gOCjhpMSfhpqZSWjEkugehB4fEWytbvsqd4CA3cNsIN7CQMBHZ3R6UmW-XS3kwAXDAUD4fYxMYEcOo2elMBdfP-uie0UbAF4a3KbJcAMEs78hqIR__9zQ_o6WAyGsrhxeW3t2i_WrW361zv0N7ybmXeA-1bRsdlJ_8NdSlSZw |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1bb9MwGLXYEBMvXMqtA4Y1wZ6WNhfbcR6rjqqDdepDhyZeLMd2tIo1iZYWFH49n3Np14m97DHJ10R2j_0d28fHCH1mKgLSSgPHBMp1CA2JE9sNPsTzrD9c4DFldyNPztn4gny7pJe3jvqqRPsqnvfS60UvnV9V2sp8ofqtTqw_nQyBkngBd_u5Tvo76DG0WT9sB-pNJ8xoPb0CGdUh3CWt5t3n_cFgaF0LI8_xvMoLmDC7_Ad9siwW_lZ-2rmy6si1c7AVTsoC6i6pD734Hyu9K668la1Gz9HPtpy1SOVXb7WMe-rvHQvIB1XEC_Ss4bB4UIe8RI9M2kFP6lMtyw7amzTr9R10NK2dsctjPNts9CqO8RGebjyzy1dIDzNrqKktBnGjHcOzPxmEmTRblvlcYUCSLAssU40vrqHQ2pgcT0uoxloODkkYAwXHJ43Cx16PT384Hp7dZPm8WLxGF6Ovs-HYaQ6AcCQNoqWTcAPjPeXyMKaSGl9LEriSy8SXXHMG6Z0xkjDDNQwrkyQy3A-kUjSJWChdQ4M3aDfNUvMOYc6jhHAWG8o0SXQUW-s_7qtAU0Ar4110aP990bTgQlSDI58LQIuo0AKXXfSlxYbIazOQe-IOATjrEOvgPR6cCXvPsgMa-v5vCNpvcSXg00JKJSgVTADhg4cHW0hbv8vu5vFJ6HYRbqEnoEOwqzwyNdmqEPaEAuCEEb8_xCY4yoFbd9HbGqyb9zetoYvCLRhvFWb7CYCzsiVvwLj_4F9-QnvTk5E4Oz3__h49rSfv7XTXB7S7vFmZj8D-lvFB1c7_AQegVOc |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Concordance+between+two+phenotypic+assays+and+ultradeep+pyrosequencing+for+determining+HIV-1+tropism&rft.jtitle=Antimicrobial+agents+and+chemotherapy&rft.au=Saliou%2C+Adrien&rft.au=Delobel%2C+Pierre&rft.au=Dubois%2C+Martine&rft.au=Nicot%2C+Florence&rft.date=2011-06-01&rft.eissn=1098-6596&rft.volume=55&rft.issue=6&rft.spage=2831&rft.epage=2836&rft_id=info:doi/10.1128%2FAAC.00091-11&rft.externalDBID=NO_FULL_TEXT |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0066-4804&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0066-4804&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0066-4804&client=summon |