Mucosal SARS-CoV-2 S1 adenovirus-based vaccine elicits robust systemic and mucosal immunity and protects against disease in animals - Aljehani, Najwa D; Tamming, Levi; Khan, Muhammad Yasir; Abdulal, Rwaa H; Alfaleh, Mohamed A; Ghazwani, Aishah; Helal, Asalah; Alsulaiman, Reem M; Sanki, Mohammad A; Alluhaybi, Khalid; Sukareh, Farah Ayman; Alharbi, Rahaf H; et al. (mBio, 2025)
Keywords: Adenoviridae - genetics; Adenoviridae - immunology; adenoviruses; Administration, Intranasal; Animals; Antibodies, Neutralizing - blood; Antibodies, Neutralizing - immunology; Antibodies, Viral - blood; COVID-19 - immunology; COVID-19 - prevention & control; COVID-19 Vaccines - administration & dosage; COVID-19 Vaccines - immunology; Cricetinae; Female; Humans; Immunity, Mucosal; Immunoglobulin G - blood; Injections, Intramuscular; Mesocricetus; Mice; Mice, Inbred BALB C; mucosal vaccines; Research Article; SARS-CoV-2; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; Spike Glycoprotein, Coronavirus - genetics; Spike Glycoprotein, Coronavirus - immunology; Vaccination; vaccine; Vaccines; SARS-CoV-2; vaccine; adenoviruses; mucosal vaccines