Placebo Response and Practice Effects in Schizophrenia Cognition Trials

• Published in: JAMA psychiatry (Chicago, Ill.) Vol. 74; no. 8; p. 807
• Main Authors: Keefe, Richard S E, Davis, Vicki G, Harvey, Philip D, Atkins, Alexandra S, Haig, George M, Hagino, Owen, Marder, Stephen, Hilt, Dana C, Umbricht, Daniel
• Format: Journal Article
• Language: English
• Published: United States 01.08.2017
• Subjects: Adult; Cognition Disorders - complications; Cognition Disorders - psychology; Controlled Clinical Trials as Topic - psychology; Female; Humans; Male; Neuropsychological Tests; Placebo Effect; Practice (Psychology); Schizophrenia - complications; Schizophrenic Psychology; Young Adult

Patients' previous experience with performance-based cognitive tests in clinical trials for cognitive impairment associated with schizophrenia can create practice-related improvements. Placebo-controlled trials for cognitive impairment associated with schizophrenia are at risk for these practic...