SARS-CoV-2 Bearing a Mutation at the S1/S2 Cleavage Site Exhibits Attenuated Virulence and Confers Protective Immunity - Sasaki, Michihito; Toba, Shinsuke; Itakura, Yukari; Chambaro, Herman M.; Kishimoto, Mai; Tabata, Koshiro; Intaruck, Kittiya; Uemura, Kentaro; Sanaki, Takao; Sato, Akihiko; Hall, William W.; Orba, Yasuko; et al. (mBio, 2021)
Keywords: Animals; Antibodies, Neutralizing - immunology; Antibodies, Viral - immunology; attenuation; Cell Line; Chlorocebus aethiops; COVID-19 - pathology; Cross Reactions - immunology; Furin - metabolism; furin cleavage site; Humans; Microbial Pathogenesis; neutralizing antibodies; Research Article; SARS-CoV-2; SARS-CoV-2 - genetics; SARS-CoV-2 - immunology; SARS-CoV-2 - pathogenicity; spike; Spike Glycoprotein, Coronavirus - genetics; Vaccines, Attenuated - immunology; Vero Cells; Virulence - genetics; neutralizing antibodies; SARS-CoV-2; attenuation; furin cleavage site; spike