Omicron Variant (B.1.1.529): Infectivity, Vaccine Breakthrough, and Antibody Resistance

• Published in: Journal of chemical information and modeling Vol. 62; no. 2; pp. 412 - 422
• Main Authors: Chen, Jiahui, Wang, Rui, Gilby, Nancy Benovich, Wei, Guo-Wei
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 24.01.2022
• Subjects: Antibodies; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Artificial Intelligence; Bioinformatics; COVID-19; COVID-19 Vaccines; Humans; Monoclonal antibodies; Mutation; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike Glycoprotein, Coronavirus; United States; Vaccines; Viral diseases; United States

The latest severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant Omicron (B.1.1.529) has ushered panic responses around the world due to its contagious and vaccine escape mutations. The essential infectivity and antibody resistance of the SARS-CoV-2 variant are determined by its mutat...