High-Throughput Screen for Inhibitors of Transglycosylase and/or Transpeptidase Activities of Escherichia coli Penicillin Binding Protein 1b

• Published in: Antimicrobial Agents and Chemotherapy Vol. 48; no. 1; pp. 30 - 40
• Main Authors: CHANDRAKALA, B, SHANDIL, Radha K, MEHRA, Upasana, SUDHA RAVISHANKAR, T, KAUR, Parvinder, USHA, Veeraraghavan, JOE, Bina, DESOUSA, Sunita M
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.01.2004
• Subjects: Anti-Bacterial Agents - pharmacology; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Proteins - antagonists & inhibitors; Bacterial Proteins - metabolism; Biological and medical sciences; Carrier Proteins; Carrier Proteins - antagonists & inhibitors; Carrier Proteins - metabolism; Detergents - pharmacology; Drug Evaluation, Preclinical; Drug Evaluation, Preclinical - methods; Enzyme Inhibitors - pharmacology; Escherichia coli; Escherichia coli - drug effects; Escherichia coli - enzymology; Glycosyltransferases; Glycosyltransferases - antagonists & inhibitors; Glycosyltransferases - metabolism; Hexosyltransferases; Hexosyltransferases - antagonists & inhibitors; Hexosyltransferases - metabolism; Mechanisms of Action: Physiological Effects; Medical sciences; Muramoylpentapeptide Carboxypeptidase; Muramoylpentapeptide Carboxypeptidase - antagonists & inhibitors; Muramoylpentapeptide Carboxypeptidase - metabolism; N-Acetylglucosaminyltransferases - antagonists & inhibitors; Penicillin-Binding Proteins; Peptidoglycan - biosynthesis; Peptidyl Transferases; Peptidyl Transferases - antagonists & inhibitors; Peptidyl Transferases - metabolism; Pharmacology. Drug treatments; Ristocetin - pharmacology; Transferases - antagonists & inhibitors; Vancomycin - pharmacology; Wheat Germ Agglutinins; Bacteria; Inhibitor; Escherichia coli; Enterobacteriaceae; Penicillin binding protein
• ISSN: 0066-4804; 1098-6596
• DOI: 10.1128/AAC.48.1.30-40.2004

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