Cytotoxic Clerodane Diterpenoids and Their Hydrolysis Products from Casearia nigrescens from the Rainforest of Madagascar - Williams, Russell B; Norris, Andrew; Miller, James S; Birkinshaw, Chris; Ratovoson, Fidy; Andriantsiferana, Rabodo; Rasamison, Vincent E; Kingston, David G. I (Journal of natural products (Washington, D.C.), 2007)
Keywords: anticarcinogenic activity; Antineoplastic Agents, Phytogenic; Antineoplastic Agents, Phytogenic - chemistry; Antineoplastic Agents, Phytogenic - isolation & purification; Antineoplastic Agents, Phytogenic - pharmacology; Biological and medical sciences; caseanigrescen; Casearia; Casearia - chemistry; Casearia nigrescens; chemical structure; chemistry; Chemistry, Medicinal; clerodane diterpene; cultured cells; cytotoxicity; Diterpenes, Clerodane; Diterpenes, Clerodane - chemistry; Diterpenes, Clerodane - isolation & purification; Diterpenes, Clerodane - pharmacology; diterpenoids; Drug Screening Assays, Antitumor; Female; Flowers; Flowers - chemistry; General pharmacology; Humans; hydrolysis; Inhibitory Concentration 50; isolation & purification; Life Sciences & Biomedicine; Madagascar; Medical sciences; Molecular Structure; nuclear magnetic resonance spectroscopy; Pharmacognosy. Homeopathy. Health food; pharmacology; Pharmacology & Pharmacy; Pharmacology. Drug treatments; Plant Leaves; Plant Leaves - chemistry; Plant Sciences; Plants, Medicinal; Plants, Medicinal - chemistry; rain forests; Salicaceae; Science & Technology; spectral analysis; stereochemistry; Madagascar; Malagasy Republic; Africa; BARK; TWIGS; LEAVES; Rain forest; Cytotoxicity; Extract; NMR spectrometry; Medicinal plant; Acetal; Ovary; Dicotyledones; Acylal; Angiospermae; Flacourtiaceae; Tumor cell; Human; Terpenoid; Flower; Pharmacognosy; Plant leaf; In vitro; Biological activity; Two dimension spectrometry; Hydrolysis; Cell line; Plant origin; Diterpene; Isolation; Spermatophyta; Degradation product; Structural analysis