Impaired Decision Making in Suicide Attempters

• Published in: The American journal of psychiatry Vol. 162; no. 2; pp. 304 - 310
• Main Authors: Jollant, Fabrice, Bellivier, Frank, Leboyer, Marion, Astruc, Bernard, Torres, Stéphane, Verdier, Régis, Castelnau, Didier, Malafosse, Alain, Courtet, Philippe
• Format: Journal Article
• Language: English
• Published: Washington, DC American Psychiatric Publishing 01.02.2005; American Psychiatric Association
• Subjects: Adult; Adult and adolescent clinical studies; Affective Symptoms - diagnosis; Affective Symptoms - psychology; Aged; Anger; Biological and medical sciences; Cognition Disorders - diagnosis; Cognition Disorders - physiopathology; Cognition Disorders - psychology; Comparative studies; Decision Making; Female; Frontal Lobe - physiopathology; Gambling; Hostility; Humans; Impulsive Behavior - diagnosis; Impulsive Behavior - psychology; Male; Medical sciences; Middle Aged; Mood Disorders - diagnosis; Mood Disorders - psychology; Neuropsychological impairment; Neuropsychological Tests - statistics & numerical data; Parasuicide; Personality Assessment; Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Risk factors; Self destructive behavior; Serotonin - physiology; Suicidal behaviour; Suicide; Suicide, Attempted - psychology; Suicides & suicide attempts; Violence - psychology; France; Europe; Anger; Social environment; Human; Impulsivity; Aggression; Decision making; Mental health; Cognition; Emotion emotionality; Personality; Experimental study; Suicide attempt; Hostility; Predictive factor; Neuropsychologia; Comparative study; Public health

OBJECTIVE: The understanding of suicidal behavior is incomplete. The stress-diathesis model suggests that a deficit in serotonergic projections to the orbitofrontal cortex is involved in susceptibility to suicidal behavior. The orbitofrontal cortex has been implicated in decision making, a cognitive...