Influence of conversion of penicillin G into a basic derivative on its accumulation and subcellular localization in cultured macrophages

• Published in: Antimicrobial Agents and Chemotherapy Vol. 31; no. 3; pp. 410 - 416
• Main Authors: RENARD, C, VANDERHAEGHE, H. J, CLAES, P. J, ZENEBERGH, A, TULKENS, P. M
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.03.1987
• Subjects: Animals; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Biological and medical sciences; Carbon Radioisotopes; Cells, Cultured; Chemical Phenomena; Chemistry; Macrophages; Macrophages - metabolism; Macrophages - ultrastructure; Medical sciences; Mice; Penicillin G; Penicillin G - analogs & derivatives; Penicillin G - metabolism; Pharmacology. Drug treatments; Research Article; Structure-Activity Relationship; Cell culture; Antibiotic; Lactam; Prodrug; In vitro; Accumulation; Uptake; Activity metabolism relation; Macrophage

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