Acousto-elasticity of Transversely Isotropic Incompressible Soft Tissues: Characterization of Skeletal Striated Muscle

• Published in: arXiv.org
• Main Authors: Remeniéras, Jean-Pierre, Bulot, Mahé, Gennisson, Jean-Luc, Fréd éric Patat, Destrade, Michel, Bacle, Guillaume
• Format: Paper Journal Article
• Language: English
• Published: Ithaca Cornell University Library, arXiv.org 17.03.2021
• Subjects: Acoustoelasticity; Modulus of elasticity; Muscles; Physics - Medical Physics; Physics - Soft Condensed Matter; S waves; Shear; Soft tissues; Stiffness
• ISSN: 2331-8422
• DOI: 10.48550/arxiv.2103.09152

Using shear wave elastography, we measure the changes in the wave speed with the stress produced by a striated muscle during isometric voluntary contraction. To isolate the behaviour of an individual muscle from complementary or antagonistic actions of adjacent muscles, we select the flexor digiti minimi muscle, whose sole function is to extend the little finger. To link the wave speed to the stiffness, we develop an acousto-elastic theory for shear waves in homogeneous, transversely isotropic, incompressible solids subject to uniaxial stress. We then provide measurements of the apparent shear elastic modulus along, and transversely to, the fibre axis for six healthy human volunteers of different age and sex. The results display a great variety across the six subjects. We find that the slope of the apparent shear elastic modulus along the fibre direction changes inversely to the maximum voluntary contraction (MVC) produced by the volunteer. We propose an interpretation of our results by introducing the S (slow) or F (fast) nature of the fibres, which harden the muscle differently and accordingly, produce different MVCs. This work opens the way to measuring the elastic stiffness of muscles in patients with musculoskeletal disorders or neurodegenerative diseases.