Localized Surface Plasmon Resonance Sensing of Lipid-Membrane-Mediated Biorecognition Events

• Published in: Journal of the American Chemical Society Vol. 127; no. 14; pp. 5043 - 5048
• Main Authors: Dahlin, Andreas, Zäch, Michael, Rindzevicius, Tomas, Käll, Mikael, Sutherland, Duncan S, Höök, Fredrik
• Format: Journal Article
• Language: English
• Published: Washington, DC American Chemical Society 13.04.2005
• Subjects: Adsorption; Biological and medical sciences; Biosensing Techniques - methods; Biosensors; Biotechnology; Biotin - chemistry; Condensed Matter Physics; Den kondenserade materiens fysik; Fundamental and applied biological sciences. Psychology; Fysik; Gold - chemistry; Lipid Bilayers - analysis; Lipid Bilayers - chemistry; Lipid Bilayers - metabolism; Membrane Lipids - analysis; Membrane Lipids - chemistry; Membrane Lipids - metabolism; Methods. Procedures. Technologies; Microscopy, Atomic Force; Natural Sciences; Naturvetenskap; Physical Sciences; Serum Albumin, Bovine - chemistry; Silicon Dioxide - chemistry; Spectroscopy, Near-Infrared; Surface Plasmon Resonance - methods; Various methods and equipments; Performance evaluation; Biosensor; Phospholipid; Molecular recognition; Single stranded DNA; Artificial membrane; Surface plasmon resonance; Bilayer

Supported phospholipid bilayers (SPBs) have emerged as important model systems for studies of the natural cell membrane and its components, which are essential for the integrity and function of cells in all living organisms, and also constitute common targets for therapeutic drugs and in disease dia...