A Perspective on Late-Stage Aromatic C–H Bond Functionalization

• Published in: Journal of the American Chemical Society Vol. 144; no. 6; pp. 2399 - 2414
• Main Authors: Zhang, Li, Ritter, Tobias
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 16.02.2022
• Subjects: Americans; area; carbon-hydrogen bond activation; chemoselectivity

Late-stage functionalization of C–H bonds (C–H LSF) can provide a straightforward approach to the efficient synthesis of functionalized complex molecules. However, C–H LSF is challenging because the C–H bond must be functionalized in the presence of various other functional groups. In this Perspecti...