Synthesis and Structure–Activity Relationship Correlations of Gnidimacrin Derivatives as Potent HIV‑1 Inhibitors and HIV Latency Reversing Agents - Liu, Qingbo; Cheng, Yung-Yi; Li, Wei; Huang, Li; Asada, Yoshihisa; Hsieh, Min-Tsang; Morris-Natschke, Susan L; Chen, Chin-Ho; Koike, Kazuo; Lee, Kuo-Hsiung (Journal of medicinal chemistry, 2019)
Keywords: Animals; Anti-HIV Agents - chemical synthesis; Anti-HIV Agents - pharmacology; Chemistry, Medicinal; Diterpenes - chemical synthesis; Diterpenes - pharmacology; HIV-1 - drug effects; HIV-1 - physiology; Humans; Life Sciences & Biomedicine; Pharmacology & Pharmacy; Plant Extracts - chemical synthesis; Plant Extracts - isolation & purification; Plant Extracts - pharmacology; Plant Roots; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species - chemical synthesis; Reactive Oxygen Species - pharmacology; Science & Technology; Structure-Activity Relationship; Virus Latency - drug effects; Virus Latency - physiology; ANTI-AIDS AGENTS; ELIMINATION; REPLICATION; DITERPENOIDS