Failure of Anterior Cingulate Activation and Connectivity With the Amygdala During Implicit Regulation of Emotional Processing in Generalized Anxiety Disorder
ObjectiveClinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the p...
Saved in:
| Published in | The American journal of psychiatry Vol. 167; no. 5; pp. 545 - 554 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Arlington, VA
American Psychiatric Association
01.05.2010
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | ObjectiveClinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the pregenual anterior cingulate regulates emotional conflict on a trial-by-trial basis by dampening activity in the amygdala. The authors also showed that this process is specific to the regulation of emotional, compared to nonemotional, conflict. Here the authors examined whether this form of noninstructed emotion regulation is perturbed in generalized anxiety disorder.
MethodSeventeen patients with generalized anxiety disorder and 24 healthy comparison subjects underwent functional MRI while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect label words. Behavioral and neural measures were used to compare trial-by-trial changes in conflict regulation.
ResultsComparison subjects effectively regulated emotional conflict from trial to trial, even though they were unaware of having done so. By contrast, patients with generalized anxiety disorder were completely unable to regulate emotional conflict and failed to engage the pregenual anterior cingulate in ways that would dampen amygdalar activity. Moreover, performance and brain activation were correlated with symptoms and could be used to accurately classify the two groups.
ConclusionsThese data demonstrate that patients with generalized anxiety disorder show significant deficits in the noninstructed and spontaneous regulation of emotional processing. Conceptualization of anxiety as importantly involving abnormalities in emotion regulation, particularly a type occurring outside of awareness, may open up avenues for novel treatments, such as by targeting the medial prefrontal cortex. |
|---|---|
| AbstractList | Clinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the pregenual anterior cingulate regulates emotional conflict on a trial-by-trial basis by dampening activity in the amygdala. The authors also showed that this process is specific to the regulation of emotional, compared to nonemotional, conflict. Here the authors examined whether this form of noninstructed emotion regulation is perturbed in generalized anxiety disorder.
Seventeen patients with generalized anxiety disorder and 24 healthy comparison subjects underwent functional MRI while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect label words. Behavioral and neural measures were used to compare trial-by-trial changes in conflict regulation.
Comparison subjects effectively regulated emotional conflict from trial to trial, even though they were unaware of having done so. By contrast, patients with generalized anxiety disorder were completely unable to regulate emotional conflict and failed to engage the pregenual anterior cingulate in ways that would dampen amygdalar activity. Moreover, performance and brain activation were correlated with symptoms and could be used to accurately classify the two groups.
These data demonstrate that patients with generalized anxiety disorder show significant deficits in the noninstructed and spontaneous regulation of emotional processing. Conceptualization of anxiety as importantly involving abnormalities in emotion regulation, particularly a type occurring outside of awareness, may open up avenues for novel treatments, such as by targeting the medial prefrontal cortex. Clinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the pregenual anterior cingulate regulates emotional conflict on a trial-by-trial basis by dampening activity in the amygdala. The authors also showed that this process is specific to the regulation of emotional, compared to nonemotional, conflict. Here the authors examined whether this form of noninstructed emotion regulation is perturbed in generalized anxiety disorder. Seventeen patients with generalized anxiety disorder and 24 healthy comparison subjects underwent functional MRI while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect label words. Behavioral and neural measures were used to compare trial-by-trial changes in conflict regulation. Comparison subjects effectively regulated emotional conflict from trial to trial, even though they were unaware of having done so. By contrast, patients with generalized anxiety disorder were completely unable to regulate emotional conflict and failed to engage the pregenual anterior cingulate in ways that would dampen amygdalar activity. Moreover, performance and brain activation were correlated with symptoms and could be used to accurately classify the two groups. These data demonstrate that patients with generalized anxiety disorder show significant deficits in the noninstructed and spontaneous regulation of emotional processing. Conceptualization of anxiety as importantly involving abnormalities in emotion regulation, particularly a type occurring outside of awareness, may open up avenues for novel treatments, such as by targeting the medial prefrontal cortex. Clinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the pregenual anterior cingulate regulates emotional conflict on a trial-by-trial basis by dampening activity in the amygdala. The authors also showed that this process is specific to the regulation of emotional, compared to nonemotional, conflict. Here the authors examined whether this form of noninstructed emotion regulation is perturbed in generalized anxiety disorder.OBJECTIVEClinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the pregenual anterior cingulate regulates emotional conflict on a trial-by-trial basis by dampening activity in the amygdala. The authors also showed that this process is specific to the regulation of emotional, compared to nonemotional, conflict. Here the authors examined whether this form of noninstructed emotion regulation is perturbed in generalized anxiety disorder.Seventeen patients with generalized anxiety disorder and 24 healthy comparison subjects underwent functional MRI while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect label words. Behavioral and neural measures were used to compare trial-by-trial changes in conflict regulation.METHODSeventeen patients with generalized anxiety disorder and 24 healthy comparison subjects underwent functional MRI while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect label words. Behavioral and neural measures were used to compare trial-by-trial changes in conflict regulation.Comparison subjects effectively regulated emotional conflict from trial to trial, even though they were unaware of having done so. By contrast, patients with generalized anxiety disorder were completely unable to regulate emotional conflict and failed to engage the pregenual anterior cingulate in ways that would dampen amygdalar activity. Moreover, performance and brain activation were correlated with symptoms and could be used to accurately classify the two groups.RESULTSComparison subjects effectively regulated emotional conflict from trial to trial, even though they were unaware of having done so. By contrast, patients with generalized anxiety disorder were completely unable to regulate emotional conflict and failed to engage the pregenual anterior cingulate in ways that would dampen amygdalar activity. Moreover, performance and brain activation were correlated with symptoms and could be used to accurately classify the two groups.These data demonstrate that patients with generalized anxiety disorder show significant deficits in the noninstructed and spontaneous regulation of emotional processing. Conceptualization of anxiety as importantly involving abnormalities in emotion regulation, particularly a type occurring outside of awareness, may open up avenues for novel treatments, such as by targeting the medial prefrontal cortex.CONCLUSIONSThese data demonstrate that patients with generalized anxiety disorder show significant deficits in the noninstructed and spontaneous regulation of emotional processing. Conceptualization of anxiety as importantly involving abnormalities in emotion regulation, particularly a type occurring outside of awareness, may open up avenues for novel treatments, such as by targeting the medial prefrontal cortex. ObjectiveClinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these abnormalities remain poorly understood at the neurobiological level. The authors recently reported that in healthy volunteers the pregenual anterior cingulate regulates emotional conflict on a trial-by-trial basis by dampening activity in the amygdala. The authors also showed that this process is specific to the regulation of emotional, compared to nonemotional, conflict. Here the authors examined whether this form of noninstructed emotion regulation is perturbed in generalized anxiety disorder. MethodSeventeen patients with generalized anxiety disorder and 24 healthy comparison subjects underwent functional MRI while performing an emotional conflict task that involved categorizing facial affect while ignoring overlaid affect label words. Behavioral and neural measures were used to compare trial-by-trial changes in conflict regulation. ResultsComparison subjects effectively regulated emotional conflict from trial to trial, even though they were unaware of having done so. By contrast, patients with generalized anxiety disorder were completely unable to regulate emotional conflict and failed to engage the pregenual anterior cingulate in ways that would dampen amygdalar activity. Moreover, performance and brain activation were correlated with symptoms and could be used to accurately classify the two groups. ConclusionsThese data demonstrate that patients with generalized anxiety disorder show significant deficits in the noninstructed and spontaneous regulation of emotional processing. Conceptualization of anxiety as importantly involving abnormalities in emotion regulation, particularly a type occurring outside of awareness, may open up avenues for novel treatments, such as by targeting the medial prefrontal cortex. |
| Author | Menon, Vinod Etkin, Amit Hoeft, Fumiko Schatzberg, Alan F. Prater, Katherine E. |
| AuthorAffiliation | 2 Center for Interdisciplinary Brain Science Research, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 1 Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 3 Program in Neuroscience, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 |
| AuthorAffiliation_xml | – name: 1 Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 – name: 2 Center for Interdisciplinary Brain Science Research, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 – name: 3 Program in Neuroscience, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305 |
| Author_xml | – sequence: 1 givenname: Amit surname: Etkin fullname: Etkin, Amit email: amitetkin@stanford.edu – sequence: 2 givenname: Katherine E. surname: Prater fullname: Prater, Katherine E. email: amitetkin@stanford.edu – sequence: 3 givenname: Fumiko surname: Hoeft fullname: Hoeft, Fumiko email: amitetkin@stanford.edu – sequence: 4 givenname: Vinod surname: Menon fullname: Menon, Vinod email: amitetkin@stanford.edu – sequence: 5 givenname: Alan F. surname: Schatzberg fullname: Schatzberg, Alan F. email: amitetkin@stanford.edu |
| BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22772572$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/20123913$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkl1v0zAYhS00xLrBX5gsJMRViz-auJYQUtV9MGkSCIHgznKdN60rx87sZKL8GH4rztoV2M2u4tjPOTr2e07QkQ8eEDqjZEKpKN_ptrUTvWknjBA5IZIIIjl9hka04MVYMDY7QiNCCBvLgv84RicpbfIv4YK9QMeMUMYl5SP0-1Jb10fAocZz30G0IeKF9ave6Q7w3HT2Tnc2eKx9hRfBexi2bLfF3223xt06Q812VWmn8XkfsxJfN62zxnb4C9zbDOpsf9GEYakd_hyDgZQG1np8BR6idvYXVDnCTwvZ-9ymECuIL9HzWrsEr_bfU_Tt8uLr4uP45tPV9WJ-M9YFnXZjxqFk1EANRi_NsiRUkpJyUwguZ7NaSCKnQgOlkhupC07rmkhZSjObVZSRgp-iDzvftl82UBnwXY6k2mgbHbcqaKv-P_F2rVbhTk15KRhh2eDt3iCG2x5SpxqbDDinPYQ-KcF5wYpCkEy-fkRuQh_zsyTFGJlKVooyQ2f_5jkEeRhcBt7sAZ2MdnXU3tj0l2NCsEIMucodZ2JIKUJ9QChRQ5PU0CSVm6SGJqmHJmXh-0fCPNH7Web7W_e0nO_k9-eHGz6h-gM2AuR7 |
| CODEN | AJPSAO |
| CitedBy_id | crossref_primary_10_1089_brain_2017_0497 crossref_primary_10_1038_s41598_019_38990_0 crossref_primary_10_1177_00207640241306062 crossref_primary_10_3389_fnbeh_2021_637426 crossref_primary_10_1016_j_nicl_2019_102016 crossref_primary_10_1038_s41386_021_00987_7 crossref_primary_10_1002_da_20799 crossref_primary_10_1016_j_neuroimage_2018_05_079 crossref_primary_10_1177_0891988714541871 crossref_primary_10_3233_JIN_170074 crossref_primary_10_1521_soco_2016_34_3_167 crossref_primary_10_1016_j_jad_2019_07_022 crossref_primary_10_1038_s41398_022_01827_y crossref_primary_10_1016_j_biopsycho_2019_03_019 crossref_primary_10_1089_cap_2015_0066 crossref_primary_10_1002_hbm_22952 crossref_primary_10_1371_journal_pone_0057111 crossref_primary_10_1016_j_ijpsycho_2014_09_003 crossref_primary_10_1093_scan_nst065 crossref_primary_10_3389_fnins_2023_1209906 crossref_primary_10_1016_j_brat_2011_12_004 crossref_primary_10_1007_s12144_012_9157_y crossref_primary_10_1016_j_psychres_2015_12_031 crossref_primary_10_1007_s11031_014_9441_2 crossref_primary_10_1093_scan_nsab057 crossref_primary_10_1016_j_janxdis_2017_04_008 crossref_primary_10_1016_j_biopsych_2014_08_006 crossref_primary_10_1017_S0033291710001455 crossref_primary_10_1016_j_jagp_2013_08_004 crossref_primary_10_1080_17470919_2017_1288657 crossref_primary_10_1016_j_neuroimage_2013_03_075 crossref_primary_10_1016_j_neubiorev_2018_11_005 crossref_primary_10_3389_fpsyg_2022_1053381 crossref_primary_10_1002_da_22859 crossref_primary_10_7759_cureus_75315 crossref_primary_10_1111_psyp_13082 crossref_primary_10_1002_trc2_12154 crossref_primary_10_1016_j_jad_2024_03_038 crossref_primary_10_1002_hbm_21179 crossref_primary_10_1016_j_jad_2014_06_041 crossref_primary_10_1016_j_biopsych_2016_12_010 crossref_primary_10_1016_j_psychres_2014_10_020 crossref_primary_10_1146_annurev_clinpsy_050212_185544 crossref_primary_10_1371_journal_pone_0124141 crossref_primary_10_1080_15289168_2020_1790083 crossref_primary_10_1016_j_jad_2024_03_032 crossref_primary_10_1590_1516_4446_2018_0108 crossref_primary_10_1177_2041669519831028 crossref_primary_10_1016_j_biopsych_2012_04_013 crossref_primary_10_1017_S0954579421001449 crossref_primary_10_1093_scan_nsu016 crossref_primary_10_1016_j_neuroimage_2018_01_080 crossref_primary_10_1186_s13587_014_0015_4 crossref_primary_10_1017_S0954579419000452 crossref_primary_10_1016_j_jaac_2020_11_023 crossref_primary_10_1073_pnas_2220353120 crossref_primary_10_1111_ejn_12939 crossref_primary_10_1016_j_jad_2018_09_049 crossref_primary_10_1177_0956797611429134 crossref_primary_10_1002_da_23252 crossref_primary_10_1111_psyp_12699 crossref_primary_10_1016_j_biopsych_2019_07_022 crossref_primary_10_1002_da_22289 crossref_primary_10_1007_s10608_017_9872_7 crossref_primary_10_1186_s12888_016_0771_3 crossref_primary_10_1016_j_ijpsycho_2020_03_004 crossref_primary_10_1016_j_nicl_2016_09_023 crossref_primary_10_1007_s11920_012_0273_z crossref_primary_10_1002_hbm_24902 crossref_primary_10_1016_j_expneurol_2016_07_021 crossref_primary_10_1093_scan_nsy049 crossref_primary_10_1093_scan_nsw091 crossref_primary_10_1111_add_16047 crossref_primary_10_1016_j_neuroimage_2018_03_028 crossref_primary_10_1002_gps_4051 crossref_primary_10_1038_s41562_019_0754_8 crossref_primary_10_1177_0886260515604411 crossref_primary_10_20996_1819_6446_2019_15_2_258_264 crossref_primary_10_1007_s10548_021_00880_y crossref_primary_10_1038_s41598_023_41357_1 crossref_primary_10_1002_da_20901 crossref_primary_10_1016_j_biopsycho_2012_02_007 crossref_primary_10_1016_j_ntt_2021_106973 crossref_primary_10_1016_j_jad_2020_02_029 crossref_primary_10_1016_j_jpsychires_2012_04_013 crossref_primary_10_1111_j_1469_8986_2011_01345_x crossref_primary_10_1371_journal_pone_0225573 crossref_primary_10_1371_journal_pone_0079184 crossref_primary_10_1038_nrn3524 crossref_primary_10_1016_j_jad_2023_03_062 crossref_primary_10_1016_j_dr_2014_12_008 crossref_primary_10_1038_s41598_017_05520_9 crossref_primary_10_1080_00332747_2015_1069656 crossref_primary_10_1016_j_ijpsycho_2019_03_015 crossref_primary_10_1016_j_pscychresns_2019_03_005 crossref_primary_10_1016_j_neuroimage_2018_03_017 crossref_primary_10_1093_scan_nsae001 crossref_primary_10_1002_da_23195 crossref_primary_10_1016_j_jad_2021_08_039 crossref_primary_10_1038_srep37633 crossref_primary_10_1017_S0954579421000663 crossref_primary_10_1089_brain_2012_0093 crossref_primary_10_1176_appi_ajp_2018_18040425 crossref_primary_10_31887_DCNS_2017_19_2_gfonzo crossref_primary_10_3402_tdp_v1i0_19673 crossref_primary_10_1016_j_bpsc_2024_08_019 crossref_primary_10_1038_s41386_019_0483_8 crossref_primary_10_1177_1362361314553280 crossref_primary_10_1176_appi_focus_16205 crossref_primary_10_1073_pnas_1910842117 crossref_primary_10_1016_j_jad_2014_01_022 crossref_primary_10_1080_02699931_2010_550505 crossref_primary_10_1177_1754073911430251 crossref_primary_10_1002_erv_2494 crossref_primary_10_5127_jep_033512 crossref_primary_10_1016_j_aip_2024_102145 crossref_primary_10_1176_appi_ajp_2015_15060710 crossref_primary_10_1016_j_bpsc_2015_12_004 crossref_primary_10_1016_j_neuroimage_2011_12_084 crossref_primary_10_1016_j_euroneuro_2017_03_004 crossref_primary_10_1002_hbm_23113 crossref_primary_10_1016_j_janxdis_2016_07_002 crossref_primary_10_1371_journal_pone_0104088 crossref_primary_10_1007_s00221_016_4660_2 crossref_primary_10_1016_j_beth_2013_12_011 crossref_primary_10_1016_j_neubiorev_2011_08_005 crossref_primary_10_1111_nejo_12427 crossref_primary_10_3724_SP_J_1042_2019_00289 crossref_primary_10_1002_brb3_1137 crossref_primary_10_1038_s41562_018_0484_3 crossref_primary_10_1016_j_biopsych_2013_11_012 crossref_primary_10_1371_journal_pone_0128608 crossref_primary_10_1186_s13063_015_0986_5 crossref_primary_10_1016_j_neuroimage_2016_04_040 crossref_primary_10_1080_17470919_2017_1403375 crossref_primary_10_1080_1047840X_2015_969624 crossref_primary_10_3389_fpsyg_2017_00001 crossref_primary_10_1007_s10608_016_9772_2 crossref_primary_10_1016_j_neuroimage_2018_10_073 crossref_primary_10_1016_j_neuroscience_2014_01_064 crossref_primary_10_1080_20008066_2023_2185414 crossref_primary_10_1111_desc_12158 crossref_primary_10_1016_j_biopsych_2013_01_036 crossref_primary_10_1080_02699931_2010_544160 crossref_primary_10_3389_fnins_2022_1022455 crossref_primary_10_1007_s11920_012_0262_2 crossref_primary_10_1016_j_bpsc_2021_02_003 crossref_primary_10_1016_j_pscychresns_2015_12_008 crossref_primary_10_1002_jmri_24970 crossref_primary_10_1097_HRP_0000000000000194 crossref_primary_10_1088_1741_2552_ab2c58 crossref_primary_10_1016_j_euroneuro_2012_04_018 crossref_primary_10_3389_fnbeh_2014_00403 crossref_primary_10_3389_fpsyt_2018_00120 crossref_primary_10_1176_appi_ajp_2019_18070870 crossref_primary_10_3389_fpsyg_2021_666284 crossref_primary_10_1186_s12888_020_02831_6 crossref_primary_10_3389_fpsyg_2015_01226 crossref_primary_10_1016_j_cbpra_2013_02_001 crossref_primary_10_1136_bmjopen_2018_022694 crossref_primary_10_3389_fnhum_2017_00492 crossref_primary_10_1038_nrn4044 crossref_primary_10_1080_10615806_2014_909928 crossref_primary_10_1016_j_paid_2017_02_017 crossref_primary_10_3389_fnbeh_2019_00273 crossref_primary_10_1038_s41562_019_0732_1 crossref_primary_10_3389_fpsyg_2016_00927 crossref_primary_10_1016_j_biopsych_2019_12_013 crossref_primary_10_1016_j_jpsychires_2022_12_002 crossref_primary_10_1016_j_neuropsychologia_2014_08_003 crossref_primary_10_1073_pnas_1307893110 crossref_primary_10_1093_scan_nsae053 crossref_primary_10_2217_npy_13_71 crossref_primary_10_1176_appi_ajp_19010091 crossref_primary_10_1523_ENEURO_0079_19_2019 crossref_primary_10_1016_j_jpsychires_2021_07_047 crossref_primary_10_1016_j_actpsy_2012_11_005 crossref_primary_10_4236_jbbs_2013_32026 crossref_primary_10_1176_appi_ajp_2019_19010091 crossref_primary_10_3390_ijms22073630 crossref_primary_10_1002_gps_4535 crossref_primary_10_1016_j_janxdis_2019_02_004 crossref_primary_10_1176_appi_ajp_2010_10010234 crossref_primary_10_1111_adb_12135 crossref_primary_10_1016_j_jad_2020_12_102 crossref_primary_10_1176_appi_focus_20102 crossref_primary_10_1002_da_21913 crossref_primary_10_1038_s41467_021_26769_9 crossref_primary_10_1177_0003065114546746 crossref_primary_10_3389_fnbeh_2015_00154 crossref_primary_10_1002_hbm_22553 crossref_primary_10_1016_j_clinimag_2012_02_006 crossref_primary_10_1016_j_pscychresns_2016_12_002 crossref_primary_10_1017_S0033291717000265 crossref_primary_10_1080_02699931_2010_532606 crossref_primary_10_1016_j_ijdevneu_2014_05_012 crossref_primary_10_1177_20451253241298871 crossref_primary_10_1016_j_nicl_2014_11_012 crossref_primary_10_1016_j_tics_2012_06_007 crossref_primary_10_1146_annurev_neuro_071714_034111 crossref_primary_10_1017_S0954579416000584 crossref_primary_10_1016_j_biopsych_2020_12_026 crossref_primary_10_1016_j_jad_2014_07_031 crossref_primary_10_1186_s41235_021_00332_y crossref_primary_10_1016_j_neuropsychologia_2024_109035 crossref_primary_10_1007_s10578_021_01150_5 crossref_primary_10_1007_s11920_018_0870_6 crossref_primary_10_1080_09540091_2022_2071839 crossref_primary_10_3389_fnbeh_2016_00008 crossref_primary_10_1038_npp_2014_311 crossref_primary_10_1007_s11682_016_9642_2 crossref_primary_10_1017_S1355617713000817 crossref_primary_10_3389_fnhum_2018_00382 crossref_primary_10_1186_s12967_021_02968_2 crossref_primary_10_1177_2158244016662106 crossref_primary_10_3389_fnins_2020_612445 crossref_primary_10_1016_j_neuropsychologia_2021_107905 crossref_primary_10_1016_j_brainres_2012_08_045 crossref_primary_10_1016_j_dcn_2019_100747 crossref_primary_10_1017_S0033291718002763 crossref_primary_10_1097_WNR_0000000000000913 crossref_primary_10_1111_jcpp_12266 crossref_primary_10_1016_j_biopsycho_2013_08_006 crossref_primary_10_1016_j_jad_2018_12_079 crossref_primary_10_1016_j_neuroscience_2014_06_040 crossref_primary_10_1038_s41380_021_01017_0 crossref_primary_10_1371_journal_pone_0055907 crossref_primary_10_1038_s41598_020_59195_w crossref_primary_10_3988_jcn_2024_0148 crossref_primary_10_1177_2470547020905787 crossref_primary_10_1002_da_22556 crossref_primary_10_1142_S2196888820500244 crossref_primary_10_1080_15294145_2016_1149777 crossref_primary_10_1038_srep41941 crossref_primary_10_1016_j_adolescence_2021_04_010 crossref_primary_10_1016_j_jecm_2012_01_006 crossref_primary_10_1007_s00429_018_1727_9 crossref_primary_10_1007_s12144_024_07129_4 crossref_primary_10_3389_fnbeh_2023_1102516 crossref_primary_10_3389_fnhum_2023_1150244 crossref_primary_10_1017_S0033291715002603 crossref_primary_10_1007_s11920_025_01600_0 crossref_primary_10_3758_s13415_011_0032_3 crossref_primary_10_1016_j_tics_2010_11_004 crossref_primary_10_1093_scan_nsx005 crossref_primary_10_1007_s12144_021_01486_0 crossref_primary_10_1016_j_jpsychires_2022_05_023 crossref_primary_10_3758_s13415_020_00789_2 crossref_primary_10_1016_j_neuropsychologia_2017_03_016 crossref_primary_10_1007_s00406_010_0147_5 crossref_primary_10_1016_j_jpsychires_2019_09_002 crossref_primary_10_1016_j_neulet_2014_10_019 crossref_primary_10_1080_13803395_2016_1230180 crossref_primary_10_1111_psyp_14355 crossref_primary_10_1016_j_bpsc_2019_07_008 crossref_primary_10_1007_s11682_020_00299_2 crossref_primary_10_1016_j_beth_2017_09_001 crossref_primary_10_1016_j_neuropsychologia_2023_108699 crossref_primary_10_1007_s00426_020_01321_4 crossref_primary_10_1016_j_neuroimage_2011_02_064 crossref_primary_10_1080_02699931_2014_994476 crossref_primary_10_1016_j_concog_2014_01_013 crossref_primary_10_1080_10926771_2014_904466 crossref_primary_10_1038_s41386_021_01186_0 crossref_primary_10_1016_j_copsyc_2014_12_027 crossref_primary_10_1080_02699931_2019_1650721 crossref_primary_10_1002_da_22014 crossref_primary_10_1002_da_22377 crossref_primary_10_1001_jamapsychiatry_2018_2172 crossref_primary_10_1007_s12144_022_03824_2 crossref_primary_10_1016_j_neuroimage_2010_11_018 crossref_primary_10_1080_17470218_2011_637114 crossref_primary_10_1521_pdps_2021_49_1_73 crossref_primary_10_1002_da_22016 crossref_primary_10_1016_j_jns_2016_10_021 crossref_primary_10_1016_j_nicl_2015_10_005 crossref_primary_10_1017_S0954579415000978 crossref_primary_10_1176_appi_ajp_2011_10091290 crossref_primary_10_3389_fnbeh_2021_601275 crossref_primary_10_1017_S0033291717001957 crossref_primary_10_3390_brainsci11091122 crossref_primary_10_3928_00485713_20110203_10 crossref_primary_10_1002_da_21957 crossref_primary_10_1016_j_jad_2011_03_040 crossref_primary_10_1016_j_neuroimage_2011_11_096 crossref_primary_10_1093_schbul_sbw012 crossref_primary_10_1016_S2215_0366_15_00579_9 crossref_primary_10_4236_health_2015_72021 crossref_primary_10_1002_hbm_23169 crossref_primary_10_3389_fpsyt_2019_00994 crossref_primary_10_1007_s00221_013_3566_5 crossref_primary_10_1016_j_jadr_2025_100895 crossref_primary_10_1111_jnp_12147 crossref_primary_10_1016_j_jad_2017_03_047 crossref_primary_10_1027_2151_2604_a000240 crossref_primary_10_3389_fnhum_2017_00549 crossref_primary_10_1016_j_bpsc_2017_08_010 crossref_primary_10_1016_j_tins_2012_04_012 crossref_primary_10_1186_s40479_015_0031_z crossref_primary_10_1007_s10899_020_09945_2 crossref_primary_10_1002_da_22140 crossref_primary_10_1007_s00146_023_01772_4 crossref_primary_10_4236_jbbs_2022_127020 crossref_primary_10_1016_j_neubiorev_2017_02_014 crossref_primary_10_1016_j_seizure_2012_04_012 crossref_primary_10_1080_17470218_2016_1199717 crossref_primary_10_3758_s13415_018_0585_5 crossref_primary_10_1371_journal_pone_0085107 crossref_primary_10_1038_s41598_017_07063_5 crossref_primary_10_1080_01480545_2023_2250576 crossref_primary_10_1162_jocn_a_00206 crossref_primary_10_1016_j_jad_2019_09_084 crossref_primary_10_3389_fpsyg_2017_00098 crossref_primary_10_1016_j_biopsycho_2011_10_016 crossref_primary_10_1146_annurev_psych_010814_015038 crossref_primary_10_1016_j_neuron_2012_06_002 crossref_primary_10_1007_s10608_022_10339_4 crossref_primary_10_1016_j_jad_2025_03_053 crossref_primary_10_1016_j_pscychresns_2018_09_006 crossref_primary_10_1016_j_cortex_2025_01_005 crossref_primary_10_1001_jamanetworkopen_2021_44759 crossref_primary_10_1002_dev_22166 crossref_primary_10_1007_s00426_020_01289_1 crossref_primary_10_1016_j_jaac_2012_12_010 crossref_primary_10_1002_da_22470 crossref_primary_10_1080_15294145_2011_10773658 crossref_primary_10_1177_15347354241269898 crossref_primary_10_1038_s41398_020_01141_5 crossref_primary_10_1016_j_biopsycho_2012_09_008 crossref_primary_10_1016_j_jad_2012_11_060 crossref_primary_10_1038_srep25826 crossref_primary_10_1162_jocn_a_02034 crossref_primary_10_1016_j_pscychresns_2015_10_009 crossref_primary_10_1017_S0033291720002275 crossref_primary_10_1186_1471_244X_14_41 crossref_primary_10_3758_s13415_022_01031_x crossref_primary_10_31887_DCNS_2017_19_2_dnutt crossref_primary_10_1016_j_pscychresns_2020_111154 crossref_primary_10_3389_fpsyt_2022_840836 crossref_primary_10_1016_j_ijpsycho_2017_07_013 crossref_primary_10_1016_j_pscychresns_2017_02_003 crossref_primary_10_1038_s41593_019_0445_9 crossref_primary_10_1002_ajmg_b_32174 crossref_primary_10_1080_10615806_2018_1489536 crossref_primary_10_1016_j_brainres_2014_01_025 crossref_primary_10_1016_j_neulet_2015_01_052 crossref_primary_10_3758_s13415_016_0415_6 crossref_primary_10_1017_S0033291713002274 crossref_primary_10_1186_s13293_024_00591_6 crossref_primary_10_1080_15294145_2011_10773663 crossref_primary_10_1177_2167702613505532 crossref_primary_10_3758_s13415_011_0030_5 crossref_primary_10_1016_j_bbr_2016_08_017 crossref_primary_10_1016_j_neuropsychologia_2015_10_029 crossref_primary_10_1016_S1516_4446_12_70056_9 crossref_primary_10_1002_hbm_25001 crossref_primary_10_1038_tp_2011_46 crossref_primary_10_1371_journal_pone_0115820 crossref_primary_10_1016_j_neulet_2017_10_031 crossref_primary_10_1177_0003065111410694 crossref_primary_10_1080_13543784_2023_2192922 crossref_primary_10_1111_nicc_12017 crossref_primary_10_1177_1475725720965761 crossref_primary_10_1007_s42761_021_00062_w crossref_primary_10_1093_scan_nsv139 crossref_primary_10_1515_ijamh_2015_0058 crossref_primary_10_3389_fpsyg_2020_586202 crossref_primary_10_1007_s00702_019_02024_w crossref_primary_10_1016_j_eatbeh_2015_05_011 crossref_primary_10_1002_hbm_22765 crossref_primary_10_1016_j_brat_2017_09_012 crossref_primary_10_1016_j_jad_2024_03_094 crossref_primary_10_1371_journal_pone_0075776 |
| Cites_doi | 10.1001/archpsyc.65.5.568 10.1038/nrn2538 10.1523/JNEUROSCI.2265-08.2008 10.1126/science.1089910 10.1037/0033-295X.108.3.624 10.1016/j.neuron.2008.06.029 10.1176/appi.ajp.2008.07101682 10.1002/mrm.10267 10.1007/s00429-005-0025-5 10.1001/archpsyc.64.1.97 10.1038/nn1051 10.1016/j.neuron.2006.07.029 10.1176/ajp.2006.163.6.1091 10.1037/0021-843X.104.1.15 10.1002/mrm.1910390305 10.1016/j.tics.2004.10.003 10.1037/0021-843X.104.1.3 10.1097/00001756-200001170-00009 10.1038/nn1594 10.1111/j.1467-9280.2007.01916.x 10.1002/hbm.460030303 10.1016/S0924-9338(97)83297-X 10.1016/j.neuroimage.2003.12.042 10.1093/cercor/bhm179 10.1016/j.beth.2006.09.001 10.1017/S0033291709005649 10.1176/appi.ajp.2008.07071060 10.1016/0005-7967(90)90135-6 10.1006/nimg.1997.0291 10.1016/j.tics.2005.03.010 10.1037/0096-3445.121.4.480 10.1016/j.neuron.2004.08.042 10.1016/S1053-8119(02)00051-4 10.1176/appi.ajp.2007.07030504 10.1016/j.neuroimage.2004.12.034 10.1016/j.brat.2006.12.004 10.1016/j.neuropsychologia.2007.01.023 10.1016/j.biopsych.2007.08.019 10.1016/j.neuroimage.2004.09.007 10.1002/hbm.460020402 10.1016/j.brat.2004.08.008 10.1016/S1053-8119(03)00169-1 10.1038/mp.2008.82 10.1038/46035 10.1016/j.neuron.2005.05.023 10.1073/pnas.97.4.1944 10.1002/(SICI)1097-0193(1996)4:1<58::AID-HBM4>3.0.CO;2-O 10.1111/j.1467-9280.2008.02061.x |
| ContentType | Journal Article |
| Copyright | Copyright © American Psychiatric Association 2010 2015 INIST-CNRS Copyright American Psychiatric Association May 2010 |
| Copyright_xml | – notice: Copyright © American Psychiatric Association 2010 – notice: 2015 INIST-CNRS – notice: Copyright American Psychiatric Association May 2010 |
| DBID | AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM K9. NAPCQ 7X8 5PM |
| DOI | 10.1176/appi.ajp.2009.09070931 |
| DatabaseName | CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Premium MEDLINE - Academic |
| DatabaseTitleList | MEDLINE ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1535-7228 |
| EndPage | 554 |
| ExternalDocumentID | PMC4367202 2025917031 20123913 22772572 10_1176_appi_ajp_2009_09070931 10.1176/appi.ajp.2009.09070931 |
| Genre | Research Support, U.S. Gov't, Non-P.H.S Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NICHD NIH HHS grantid: 5K23HD054720 – fundername: NICHD NIH HHS grantid: K23 HD054720 – fundername: NICHD NIH HHS grantid: R01 HD047520 – fundername: NICHD NIH HHS grantid: HD047520 – fundername: NINDS NIH HHS grantid: R21 NS058899 – fundername: NINDS NIH HHS grantid: NS058899 |
| GroupedDBID | --- --Z -DZ -~X .55 0WA 1HT 1QT 23M 2WC 4.4 53G 5GY 5RE 6J9 7K8 85S 8R4 8R5 AAIKC AAMNW AAWTL AAWTO ABIVO ABPPZ ABZEH ACBMB ACGFO ACGOD ACHQT ACNCT ADBBV ADCOW AENEX AETEA AFAZI AFMIJ AFOSN AGHSJ AGNAY AHMBA AIZTS ALMA_UNASSIGNED_HOLDINGS ASUFR BAJDF BAWUL BCR BENPR BKOMP BLC CS3 DIK E3Z EBS EJD EX3 F5P F8P FJW G0H HF~ HZ~ L7B MVM N4W N9A NHB OK1 P2P PEA PQQKQ Q.- Q2X RAY RWL RXW RYA S10 SJN TAE TEORI TR2 TWZ UHB UKR ULE UPT VVN WH7 WOQ WOW X6Y X7M XJT XOL XSW XZL YCJ YFH YOC YSK YWH YZZ ZCA ZHY ZRR ZY1 ~A~ ~G0 AAJMC AAYXX ADMHG CITATION H13 .GJ 08P 1CY 1KJ 2QL 354 3O- 41~ 6TJ 8F7 AAAHA AAKAS AAQQT AAYJJ ABDPE ADZCM AERZD AFFNX AHJKT AI. FA8 GOZPB GRPMH IQODW J5H LPU LXL LXN NEJ OHT OVD P-O SKT UBC UQL VH1 WHG X4V YQI YQJ YRY YXB YYQ ZGI ZKB ZXP ~X8 CGR CUY CVF ECM EIF NPM K9. NAPCQ 7X8 5PM ADXHL |
| ID | FETCH-LOGICAL-a514t-23e621cefecabcb60190613c573988f790947ae1193c9a531ff09969c88d12053 |
| ISSN | 0002-953X 1535-7228 |
| IngestDate | Thu Aug 21 14:06:25 EDT 2025 Fri Jul 11 09:13:16 EDT 2025 Sun Jun 29 16:39:39 EDT 2025 Thu Apr 03 06:59:43 EDT 2025 Wed Apr 02 07:16:21 EDT 2025 Tue Jul 01 01:51:35 EDT 2025 Thu Apr 24 22:58:20 EDT 2025 Wed Jul 24 08:10:55 EDT 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Affect affectivity Amygdala Central nervous system Anxiety disorder Cognition Basal ganglion Activation Emotion emotionality Encephalon Cingulate cortex Generalized anxiety disorder Information processing Amygdaloid nucleus Failure |
| Language | English |
| License | CC BY 4.0 |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-a514t-23e621cefecabcb60190613c573988f790947ae1193c9a531ff09969c88d12053 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/4367202 |
| PMID | 20123913 |
| PQID | 220492676 |
| PQPubID | 40661 |
| PageCount | 10 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_4367202 proquest_miscellaneous_733525570 proquest_journals_220492676 pubmed_primary_20123913 pascalfrancis_primary_22772572 crossref_primary_10_1176_appi_ajp_2009_09070931 crossref_citationtrail_10_1176_appi_ajp_2009_09070931 appi_journals_10_1176_appi_ajp_2009_09070931 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2010-05-01 |
| PublicationDateYYYYMMDD | 2010-05-01 |
| PublicationDate_xml | – month: 05 year: 2010 text: 2010-05-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Arlington, VA |
| PublicationPlace_xml | – name: Arlington, VA – name: United States – name: Washington |
| PublicationTitle | The American journal of psychiatry |
| PublicationTitleAlternate | Am J Psychiatry |
| PublicationYear | 2010 |
| Publisher | American Psychiatric Association |
| Publisher_xml | – name: American Psychiatric Association |
| References | Mennin, DS 2007; 45 Carter, CS 1999; 402 Phillips, ML 2008; 13 Ochsner, KN 2005; 9 Habel, U 2005; 210 Poline, JB 1995; 2 Mohlberg, H 2005; 25 Van Bavel, JJ 2008; 19 Farach, FJ 2007; 45 Weiller, E 1997; 12 Metzger, RL 1990; 28 Egner, T 2005; 24 Crockett, MJ 2007; 18 Friston, KJ 1996; 4 Blair, RJ 2007; 64 Buckley, MJ 2009; 10 Derntl, B 2007; 45 Johnstone, T 2007; 63 Janavs, J 1998; 59 Gur, RC 2007; 45 Shaywitz, J 2008; 165 Bonora, LI 1997; 12 Spielman, DM 2002; 48 Worsley, KJ 1995; 2 McLaughlin, KA 2007; 45 Burdette, JH 2003; 19 Donchin, E 1992; 121 Mazziotta, JC 2000; 11 Vandal, AC 1996; 4 Carter, CS 2001; 108 Phelps, EA 2008; 59 Holmes, AP 1995; 2 Gross, JJ 2005; 9 Leibenluft, E 2007; 64 Ingvar, M 2005; 46 Drevets, WC 2008; 13 Jacobs, M 2008; 165 Liberzon, I 2003; 18 Smith, BW 2008; 165 Mondillo, K 2008; 165 Ernst, M 2006; 163 Cohen, JD 2004; 8 Adalsteinsson, E 2002; 48 Bookheimer, SY 2000; 11 Monk, CS 2007; 64 Charney, DS 2006; 163 Egner, T 2008; 18 Polis, S 2007; 63 Awh, E 2003; 6 Macdonald, AM 2000; 97 Hirsch, J 2008; 18 Ladouceur, CD 2008; 13 Carter, CS 2000; 97 Schinka, J 1997; 12 Mennin, DS 2007; 38 Davidson, RJ 2009; 166 Sambugaro, E 2010; 40 Petrovic, P 2005; 46 Nelson, EE 2006; 163 Frackowiak, RS 1995; 2 Davidson, RJ 2007; 63 Nitschke, JB 2009; 166 Kumar, R 2004; 22 MacDonald, AW 2004; 303 Hirsch, J 2005; 8 Coles, MG 1992; 121 Moser, E 2007; 45 Sassaroli, S 2010; 40 Bottini, G 2010; 40 Watson, D 1995; 104 Adler, A 2007; 64 Macey, PM 2004; 22 Fromm, S 2007; 64 Botvinick, MM 2004; 8 Lai, S 1998; 39 Dunbar, GC 1998; 59 Turk, CL 2005; 43 Jones, M 2008; 165 Cohen, JD 2000; 97 Tanaka, K 2009; 10 Laurey, P 2003; 6 Scialfa, G 2010; 40 Ross, LL 2000; 97 Fresco, DM 2005; 43 Danelli, L 2010; 40 Ruggiero, GM 2010; 40 Pieperhoff, P 2005; 210 Schneider, F 2005; 210 Etkin, A Heimberg, RG 2005; 43 Schatzberg, AF Behar, E 2004 LeDoux, JE 2004; 43 Amunts, K 2005; 25 Ernst, M 2007; 64 Paulesu, E 2010; 40 Holaway, RM 2007; 38 Cunningham, WA 2008; 19 Mansouri, FA 2009; 10 Tom, SM 2007; 18 Vythilingam, M 2008; 165 Glover, GH 2002; 48 Carter, CS 2004; 303 Egner, T 2006; 51 Hergueta, T 1998; 59 Dunbar, GC 1997; 12 Friston, KJ 1995; 2 Torti, T 2010; 40 Menon, V Delgado, MR 2004; 43 Chen, G 2008; 65 Weiller, E 1998; 59 Greicius, MD Windischberger, C 2007; 45 Botvinick, M 2000; 97 Cho, RY 2004; 303 Carter, CS 2004; 8 Grefkes, C 2005; 25 Worsley, KJ 1996; 4 Prater, KE Ernst, M 2008; 65 Pine, DS 2008; 165 Kindler, M 2005; 210 Phelps, EA 2004; 43 Fink, GR 2005; 25 Phelps, EA 2008; 28 McClure-Tone, EB 2008; 65 Blair, RJ 2008; 165 Etkin, A 2007; 164 Whalen, PJ 2009; 166 Etkin, A 2008; 18 Telzer, EH 2008; 65 Kandel, ER 2006; 51 Ledoux, JE 2008; 59 Miller, ML 1990; 28 Johnsen, IR 2008; 19 Nystrom, LE 1999; 402 Lieberman, MD 2007; 18 Somerville, LH 2007; 63 Botvinick, MM 2001; 108 Eickhoff, SB 2005; 25 Zilles, K 2005; 25 Charney, DS 2007; 64 McCormick, RA 1995; 104 Bradley, BP 2008; 65 Pine, DS 2006; 163 Blair, RJR 2006; 163 Botvinick, M 1999; 402 Bradley, BP 2006; 163 Meyer, TJ 1990; 28 Whalen, PJ 2007; 63 Leibenluft, E 2006; 163 Hariri, AR 2000; 11 Stenger, VA 2000; 97 Andersson, J 2005; 46 Clark, LA 1995; 104 Evans, AC 1996; 4 Monk, CS 2008; 65 Decker, LR 2003; 18 Taylor, SF 2003; 18 Knapp, E 1997; 12 Mogg, K 2008; 65 Marrett, S 1996; 4 Hirsch, J 2006; 51 Carlsson, K 2005; 46 LeDoux, JE 2008; 28 Neelin, P 1996; 4 Kryspin-Exner, I 2007; 45 Noll, D 2000; 97 Sarinopoulos, I 2009; 166 Fransson, P 2005; 46 Amorim, P 1998; 59 Parrish, JM 2007; 64 Assenheimer, JS 1995; 104 Dietrich, T 2005; 46 Pine, DS 2007; 64 Peraza, DM 2006; 51 Way, BM 2007; 18 Morris, J 1997; 6 Niv, Y 2008; 28 Ashburner, J 1995; 2 Dolan, RJ 1997; 6 Mohlberg, H 2005; 210 Delgado, MR 2008; 59 Schiller, D 2008; 28 Drevets, WC 2008; 165 Oathes, DJ 2009; 166 Cohen, JD 1999; 402 Chen, G 2006; 163 Gratton, G 1992; 121 Buechel, C 1997; 6 Fissell, K 1999; 402 Mogg, K 2006; 163 Harnett-Sheehan, K 1997; 12 Mennin, DS 2005; 43 Habel, U 2007; 45 Moore, MT 2007; 38 Nearing, KI 2004; 43 Stephan, KE 2005; 25 Frith, CD 1995; 2 Harper, RM 2004; 22 Wager, TD 2007; 164 Amunts, K 2005; 210 Alcaine, O 2004 Levy, I 2008; 28 Rhodes, R 2008; 165 Kerns, JG 2004; 303 Kalin, NH 2007; 63 Sheehan, KH 1998; 59 Mai, X 2008; 65 Mayr, U 2003; 6 Egner, T 2005; 8 Gale, S 2008; 18 Geraci, M 2008; 165 Sberna, M 2010; 40 Borkovec, TD 1990; 28 Sheehan, MF 1997; 12 McClure, EB 2006; 163 Cohen, JD 2004; 303 Turk, CL 2004 Maldjian, JA 2003; 19 Eisenberger, NI 2007; 18 Baker, R 1998; 59 Etkin, A 2006; 51 Zilles, K 2005; 210 Robinson, S 2007; 45 Cohen, JD 2001; 108 Ferri, F 2010; 40 Borkovec, TD 2004 Rolls, E 1997; 6 Hirsch, J 2005; 24 Pine, DS 2008; 65 Louro, HM 2008; 65 Kedo, O 2005; 210 Laurienti, PJ 2003; 19 Nelson, EE 2007; 64 Fink, GR 1997; 6 McCaffrey, D 2008; 165 Fresco, DM 2007; 38 Mennin, DS 2004 Blair, K 2008; 165 Heimberg, RG 2004 Sheehan, DV 1997; 12 Lecrubier, Y 1997; 12 Strauss, ME 1995; 104 Barch, DM 2001; 108 Sheehan, DV 1998; 59 Shah, NJ 2005; 210 Heimberg, RG 2007; 38 Finger, E 2008; 165 Glover, GH 1998; 39 Lecrubier, Y 1998; 59 McClure, EB 2007; 64 Stenger, VA 2004; 303 Nearing, KI 2008; 59 Kim, DH 2002; 48 Braver, TS 2001; 108 Kalin, NH 2009; 166 Nitschke, JB 2007; 63 Phan, KL 2003; 18 Janavs, J 1997; 12 Weber, K 1995; 104 Macey, KE 2004; 22 Johnstone, T 2009; 166 Keskiner, A 1997; 12 Heather, JD 1995; 2 Kraft, RA 2003; 19 Pfeifer, JH 2007; 18 Monk, CS 2006; 163 Charney, DS 2008; 165 Alexander, AL 2007; 63 Friston, KJ 1997; 6 ajp0931r31 ajp0931r36 ajp0931r2 ajp0931r3 ajp0931r33 ajp0931r39 ajp0931r37 ajp0931r4 ajp0931r5 ajp0931r6 ajp0931r7 ajp0931r8 ajp0931r9 ajp0931r43 ajp0931r42 ajp0931r41 ajp0931r40 ajp0931r47 Ekman P (ajp0931r38) 1976 ajp0931r46 ajp0931r45 ajp0931r44 ajp0931r49 ajp0931r48 ajp0931r50 ajp0931r10 ajp0931r54 ajp0931r53 ajp0931r52 Spielberger CD (ajp0931r32) 1970 ajp0931r14 ajp0931r13 ajp0931r57 ajp0931r56 ajp0931r11 ajp0931r55 ajp0931r18 ajp0931r17 ajp0931r16 Etkin A (ajp0931r12) ajp0931r15 (ajp0931r1) 1994 ajp0931r19 Beck AT (ajp0931r34) 1993 ajp0931r21 ajp0931r20 ajp0931r25 ajp0931r24 ajp0931r23 ajp0931r22 ajp0931r29 ajp0931r28 ajp0931r27 ajp0931r26 Sheehan DV (ajp0931r30) 1998; 59 Beck AT (ajp0931r35) 1996 Etkin A (ajp0931r51) 9881538 - J Clin Psychiatry. 1998;59 Suppl 20:22-33;quiz 34-57 15866151 - Trends Cogn Sci. 2005 May;9(5):242-9 16741211 - Am J Psychiatry. 2006 Jun;163(6):1091-7 12353290 - Magn Reson Med. 2002 Oct;48(4):715-22 17964548 - Biol Psychiatry. 2008 May 1;63(9):858-63 15363399 - Neuron. 2004 Sep 16;43(6):897-905 1431740 - J Exp Psychol Gen. 1992 Dec;121(4):480-506 7897037 - J Abnorm Psychol. 1995 Feb;104(1):15-25 12667842 - Neuroimage. 2003 Mar;18(3):650-9 18987188 - J Neurosci. 2008 Nov 5;28(45):11517-25 15110027 - Neuroimage. 2004 May;22(1):360-6 18458208 - Arch Gen Psychiatry. 2008 May;65(5):568-76 15627596 - Neuroimage. 2005 Jan 15;24(2):539-47 21309113 - Curr Top Behav Neurosci. 2010;2:251-77 17940084 - Cereb Cortex. 2008 Jun;18(6):1475-84 10647008 - Nature. 1999 Nov 11;402(6758):179-81 17408704 - Neuropsychologia. 2007 Jun 11;45(10):2369-77 12880848 - Neuroimage. 2003 Jul;19(3):1233-9 18574483 - Mol Psychiatry. 2008 Sep;13(9):829, 833-57 11488380 - Psychol Rev. 2001 Jul;108(3):624-52 12704394 - Nat Neurosci. 2003 May;6(5):450-2 9344826 - Neuroimage. 1997 Oct;6(3):218-29 19996041 - Arch Gen Psychiatry. 2009 Dec;66(12):1361-72 17697853 - Behav Ther. 2007 Sep;38(3):284-302 19122007 - Am J Psychiatry. 2009 Mar;166(3):302-10 17199059 - Arch Gen Psychiatry. 2007 Jan;64(1):97-106 17576282 - Psychol Sci. 2007 May;18(5):421-8 19153577 - Nat Rev Neurosci. 2009 Feb;10(2):141-52 9498591 - Magn Reson Med. 1998 Mar;39(3):361-8 16086981 - Behav Res Ther. 2005 Oct;43(10):1281-310 15556023 - Trends Cogn Sci. 2004 Dec;8(12):539-46 10683827 - Neuroreport. 2000 Jan 17;11(1):43-8 7897050 - J Abnorm Psychol. 1995 Feb;104(1):3-14 20439393 - Am J Psychiatry. 2010 May;167(5):489-92 14963333 - Science. 2004 Feb 13;303(5660):1023-6 2076086 - Behav Res Ther. 1990;28(6):487-95 19419593 - Psychol Med. 2010 Jan;40(1):117-24 16286928 - Nat Neurosci. 2005 Dec;8(12):1784-90 10677559 - Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1944-8 16208455 - Anat Embryol (Berl). 2005 Dec;210(5-6):343-52 18786365 - Neuron. 2008 Sep 11;59(5):829-38 15953423 - Neuron. 2005 Jun 16;46(6):957-69 16982430 - Neuron. 2006 Sep 21;51(6):871-82 20408186 - Hum Brain Mapp. 1996;4(1):58-73 18483136 - Am J Psychiatry. 2008 Sep;165(9):1193-202 18271863 - Psychol Sci. 2008 Feb;19(2):152-60 15850749 - Neuroimage. 2005 May 1;25(4):1325-35 17270145 - Behav Res Ther. 2007 Aug;45(8):1735-52 17898336 - Am J Psychiatry. 2007 Oct;164(10 ):1476-88 |
| References_xml | – volume: 43 start-page: 1281 year: 2005 end-page: 1310 article-title: Preliminary evidence for an emotion dysregulation model of generalized anxiety disorder publication-title: Behav Res Ther – article-title: Disrupted amygdalar subregion functional connectivity and evidence for a compensatory network in generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 108 start-page: 624 year: 2001 end-page: 652 article-title: Conflict monitoring and cognitive control publication-title: Psychol Rev – volume: 59 start-page: 829 year: 2008 end-page: 838 article-title: Neural circuitry underlying the regulation of conditioned fear and its relation to extinction publication-title: Neuron – volume: 43 start-page: 897 year: 2004 end-page: 905 article-title: Extinction learning in humans: role of the amygdala and vmPFC publication-title: Neuron – volume: 104 start-page: 15 year: 1995 end-page: 25 article-title: Testing a tripartite model, II: exploring the symptom structure of anxiety and depression in student, adult, and patient samples publication-title: J Abnorm Psychol – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 2 start-page: 165 year: 1995 end-page: 189 article-title: Spatial registration and normalization of images publication-title: Hum Brain Mapp – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 4 start-page: 58 year: 1996 end-page: 73 article-title: A unified statistical approach for determining significant signals in images of cerebral activation publication-title: Hum Brain Mapp – volume: 45 start-page: 1735 year: 2007 end-page: 1752 article-title: The contributory role of worry in emotion generation and dysregulation in generalized anxiety disorder publication-title: Behav Res Ther – volume: 6 start-page: 218 year: 1997 end-page: 229 article-title: Psychophysiological and modulatory interactions in neuroimaging publication-title: Neuroimage – volume: 6 start-page: 218 year: 1997 end-page: 229 article-title: Psychophysiological and modulatory interactions in neuroimaging publication-title: Neuroimage – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 8 start-page: 539 year: 2004 end-page: 546 article-title: Conflict monitoring and anterior cingulate cortex: an update publication-title: Trends Cogn Sci – volume: 18 start-page: 650 year: 2003 end-page: 659 article-title: Subjective rating of emotionally salient stimuli modulates neural activity publication-title: Neuroimage – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 402 start-page: 179 year: 1999 end-page: 181 article-title: Conflict monitoring versus selection-for-action in anterior cingulate cortex publication-title: Nature – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 28 start-page: 11517 year: 2008 end-page: 11525 article-title: From fear to safety and back: reversal of fear in the human brain publication-title: J Neurosci – volume: 18 start-page: 1475 year: 2008 end-page: 1484 article-title: Dissociable neural systems resolve conflict from emotional versus nonemotional distracters publication-title: Cereb Cortex – volume: 2 start-page: 189 year: 1995 end-page: 210 article-title: Statistical parametric maps in functional imaging: a general linear approach publication-title: Hum Brain Mapp – volume: 18 start-page: 650 year: 2003 end-page: 659 article-title: Subjective rating of emotionally salient stimuli modulates neural activity publication-title: Neuroimage – volume: 10 start-page: 141 year: 2009 end-page: 152 article-title: Conflict-induced behavioural adjustment: a clue to the executive functions of the prefrontal cortex publication-title: Nat Rev Neurosci – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 13 start-page: 829 833 year: 2008 end-page: 857 article-title: A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder publication-title: Mol Psychiatry – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 104 start-page: 15 year: 1995 end-page: 25 article-title: Testing a tripartite model, II: exploring the symptom structure of anxiety and depression in student, adult, and patient samples publication-title: J Abnorm Psychol – volume: 18 start-page: 1475 year: 2008 end-page: 1484 article-title: Dissociable neural systems resolve conflict from emotional versus nonemotional distracters publication-title: Cereb Cortex – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 46 start-page: 957 year: 2005 end-page: 969 article-title: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network publication-title: Neuron – volume: 104 start-page: 3 year: 1995 end-page: 14 article-title: Testing a tripartite model, I: evaluating the convergent and discriminant validity of anxiety and depression symptom scales publication-title: J Abnorm Psychol – volume: 46 start-page: 957 year: 2005 end-page: 969 article-title: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network publication-title: Neuron – volume: 28 start-page: 487 year: 1990 end-page: 495 article-title: Development and validation of the Penn State Worry Questionnaire publication-title: Behav Res Ther – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 48 start-page: 715 year: 2002 end-page: 722 article-title: Regularized higher-order in vivo shimming publication-title: Magn Reson Med – volume: 22 start-page: 360 year: 2004 end-page: 366 article-title: A method for removal of global effects from fMRI time series publication-title: Neuroimage – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 121 start-page: 480 year: 1992 end-page: 506 article-title: Optimizing the use of information: strategic control of activation of responses publication-title: J Exp Psychol Gen – volume: 402 start-page: 179 year: 1999 end-page: 181 article-title: Conflict monitoring versus selection-for-action in anterior cingulate cortex publication-title: Nature – volume: 51 start-page: 871 year: 2006 end-page: 882 article-title: Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala publication-title: Neuron – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – volume: 164 start-page: 1476 year: 2007 end-page: 1488 article-title: Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia publication-title: Am J Psychiatry – start-page: 77 year: 2004 end-page: 108 article-title: Avoidance theory of worry and generalized anxiety disorder, in Generalized Anxiety Disorder: Advances in Research and Practice – volume: 10 start-page: 141 year: 2009 end-page: 152 article-title: Conflict-induced behavioural adjustment: a clue to the executive functions of the prefrontal cortex publication-title: Nat Rev Neurosci – volume: 6 start-page: 450 year: 2003 end-page: 452 article-title: Conflict adaptation effects in the absence of executive control publication-title: Nat Neurosci – volume: 303 start-page: 1023 year: 2004 end-page: 1026 article-title: Anterior cingulate conflict monitoring and adjustments in control publication-title: Science – start-page: 77 year: 2004 end-page: 108 article-title: Avoidance theory of worry and generalized anxiety disorder, in Generalized Anxiety Disorder: Advances in Research and Practice – volume: 28 start-page: 11517 year: 2008 end-page: 11525 article-title: From fear to safety and back: reversal of fear in the human brain publication-title: J Neurosci – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 11 start-page: 43 year: 2000 end-page: 48 article-title: Modulating emotional responses: effects of a neocortical network on the limbic system publication-title: Neuroreport – volume: 2 start-page: 165 year: 1995 end-page: 189 article-title: Spatial registration and normalization of images publication-title: Hum Brain Mapp – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 28 start-page: 487 year: 1990 end-page: 495 article-title: Development and validation of the Penn State Worry Questionnaire publication-title: Behav Res Ther – volume: 2 start-page: 189 year: 1995 end-page: 210 article-title: Statistical parametric maps in functional imaging: a general linear approach publication-title: Hum Brain Mapp – volume: 11 start-page: 43 year: 2000 end-page: 48 article-title: Modulating emotional responses: effects of a neocortical network on the limbic system publication-title: Neuroreport – volume: 38 start-page: 284 year: 2007 end-page: 302 article-title: Delineating components of emotion and its dysregulation in anxiety and mood psychopathology publication-title: Behav Ther – start-page: 77 year: 2004 end-page: 108 article-title: Avoidance theory of worry and generalized anxiety disorder, in Generalized Anxiety Disorder: Advances in Research and Practice – volume: 28 start-page: 11517 year: 2008 end-page: 11525 article-title: From fear to safety and back: reversal of fear in the human brain publication-title: J Neurosci – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 45 start-page: 1735 year: 2007 end-page: 1752 article-title: The contributory role of worry in emotion generation and dysregulation in generalized anxiety disorder publication-title: Behav Res Ther – volume: 2 start-page: 189 year: 1995 end-page: 210 article-title: Statistical parametric maps in functional imaging: a general linear approach publication-title: Hum Brain Mapp – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 39 start-page: 361 year: 1998 end-page: 368 article-title: Self-navigated spiral fMRI: interleaved versus single-shot publication-title: Magn Reson Med – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 2 start-page: 165 year: 1995 end-page: 189 article-title: Spatial registration and normalization of images publication-title: Hum Brain Mapp – volume: 4 start-page: 58 year: 1996 end-page: 73 article-title: A unified statistical approach for determining significant signals in images of cerebral activation publication-title: Hum Brain Mapp – volume: 2 start-page: 189 year: 1995 end-page: 210 article-title: Statistical parametric maps in functional imaging: a general linear approach publication-title: Hum Brain Mapp – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 4 start-page: 58 year: 1996 end-page: 73 article-title: A unified statistical approach for determining significant signals in images of cerebral activation publication-title: Hum Brain Mapp – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 13 start-page: 829 833 year: 2008 end-page: 857 article-title: A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder publication-title: Mol Psychiatry – volume: 18 start-page: 421 year: 2007 end-page: 428 article-title: Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli publication-title: Psychol Sci – volume: 9 start-page: 242 year: 2005 end-page: 249 article-title: The cognitive control of emotion publication-title: Trends Cogn Sci – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 4 start-page: 58 year: 1996 end-page: 73 article-title: A unified statistical approach for determining significant signals in images of cerebral activation publication-title: Hum Brain Mapp – volume: 22 start-page: 360 year: 2004 end-page: 366 article-title: A method for removal of global effects from fMRI time series publication-title: Neuroimage – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 18 start-page: 421 year: 2007 end-page: 428 article-title: Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli publication-title: Psychol Sci – volume: 28 start-page: 487 year: 1990 end-page: 495 article-title: Development and validation of the Penn State Worry Questionnaire publication-title: Behav Res Ther – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 24 start-page: 539 year: 2005 end-page: 547 article-title: The neural correlates and functional integration of cognitive control in a Stroop task publication-title: Neuroimage – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – article-title: Disrupted amygdalar subregion functional connectivity and evidence for a compensatory network in generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 303 start-page: 1023 year: 2004 end-page: 1026 article-title: Anterior cingulate conflict monitoring and adjustments in control publication-title: Science – volume: 108 start-page: 624 year: 2001 end-page: 652 article-title: Conflict monitoring and cognitive control publication-title: Psychol Rev – volume: 6 start-page: 450 year: 2003 end-page: 452 article-title: Conflict adaptation effects in the absence of executive control publication-title: Nat Neurosci – volume: 2 start-page: 165 year: 1995 end-page: 189 article-title: Spatial registration and normalization of images publication-title: Hum Brain Mapp – volume: 19 start-page: 1233 year: 2003 end-page: 1239 article-title: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets publication-title: Neuroimage – volume: 43 start-page: 1281 year: 2005 end-page: 1310 article-title: Preliminary evidence for an emotion dysregulation model of generalized anxiety disorder publication-title: Behav Res Ther – volume: 104 start-page: 3 year: 1995 end-page: 14 article-title: Testing a tripartite model, I: evaluating the convergent and discriminant validity of anxiety and depression symptom scales publication-title: J Abnorm Psychol – volume: 104 start-page: 15 year: 1995 end-page: 25 article-title: Testing a tripartite model, II: exploring the symptom structure of anxiety and depression in student, adult, and patient samples publication-title: J Abnorm Psychol – article-title: Disrupted amygdalar subregion functional connectivity and evidence for a compensatory network in generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 28 start-page: 487 year: 1990 end-page: 495 article-title: Development and validation of the Penn State Worry Questionnaire publication-title: Behav Res Ther – volume: 303 start-page: 1023 year: 2004 end-page: 1026 article-title: Anterior cingulate conflict monitoring and adjustments in control publication-title: Science – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 10 start-page: 141 year: 2009 end-page: 152 article-title: Conflict-induced behavioural adjustment: a clue to the executive functions of the prefrontal cortex publication-title: Nat Rev Neurosci – volume: 43 start-page: 897 year: 2004 end-page: 905 article-title: Extinction learning in humans: role of the amygdala and vmPFC publication-title: Neuron – volume: 18 start-page: 421 year: 2007 end-page: 428 article-title: Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli publication-title: Psychol Sci – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 104 start-page: 3 year: 1995 end-page: 14 article-title: Testing a tripartite model, I: evaluating the convergent and discriminant validity of anxiety and depression symptom scales publication-title: J Abnorm Psychol – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 46 start-page: 957 year: 2005 end-page: 969 article-title: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network publication-title: Neuron – volume: 48 start-page: 715 year: 2002 end-page: 722 article-title: Regularized higher-order in vivo shimming publication-title: Magn Reson Med – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 108 start-page: 624 year: 2001 end-page: 652 article-title: Conflict monitoring and cognitive control publication-title: Psychol Rev – volume: 104 start-page: 3 year: 1995 end-page: 14 article-title: Testing a tripartite model, I: evaluating the convergent and discriminant validity of anxiety and depression symptom scales publication-title: J Abnorm Psychol – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 303 start-page: 1023 year: 2004 end-page: 1026 article-title: Anterior cingulate conflict monitoring and adjustments in control publication-title: Science – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 43 start-page: 897 year: 2004 end-page: 905 article-title: Extinction learning in humans: role of the amygdala and vmPFC publication-title: Neuron – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – start-page: 77 year: 2004 end-page: 108 article-title: Avoidance theory of worry and generalized anxiety disorder, in Generalized Anxiety Disorder: Advances in Research and Practice – volume: 38 start-page: 284 year: 2007 end-page: 302 article-title: Delineating components of emotion and its dysregulation in anxiety and mood psychopathology publication-title: Behav Ther – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 46 start-page: 957 year: 2005 end-page: 969 article-title: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network publication-title: Neuron – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 4 start-page: 58 year: 1996 end-page: 73 article-title: A unified statistical approach for determining significant signals in images of cerebral activation publication-title: Hum Brain Mapp – volume: 38 start-page: 284 year: 2007 end-page: 302 article-title: Delineating components of emotion and its dysregulation in anxiety and mood psychopathology publication-title: Behav Ther – volume: 59 start-page: 829 year: 2008 end-page: 838 article-title: Neural circuitry underlying the regulation of conditioned fear and its relation to extinction publication-title: Neuron – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 19 start-page: 152 year: 2008 end-page: 160 article-title: Affective flexibility: evaluative processing goals shape amygdala activity publication-title: Psychol Sci – volume: 2 start-page: 165 year: 1995 end-page: 189 article-title: Spatial registration and normalization of images publication-title: Hum Brain Mapp – volume: 51 start-page: 871 year: 2006 end-page: 882 article-title: Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala publication-title: Neuron – volume: 19 start-page: 152 year: 2008 end-page: 160 article-title: Affective flexibility: evaluative processing goals shape amygdala activity publication-title: Psychol Sci – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 46 start-page: 957 year: 2005 end-page: 969 article-title: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network publication-title: Neuron – volume: 18 start-page: 421 year: 2007 end-page: 428 article-title: Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli publication-title: Psychol Sci – volume: 59 start-page: 829 year: 2008 end-page: 838 article-title: Neural circuitry underlying the regulation of conditioned fear and its relation to extinction publication-title: Neuron – volume: 303 start-page: 1023 year: 2004 end-page: 1026 article-title: Anterior cingulate conflict monitoring and adjustments in control publication-title: Science – volume: 6 start-page: 218 year: 1997 end-page: 229 article-title: Psychophysiological and modulatory interactions in neuroimaging publication-title: Neuroimage – volume: 38 start-page: 284 year: 2007 end-page: 302 article-title: Delineating components of emotion and its dysregulation in anxiety and mood psychopathology publication-title: Behav Ther – volume: 8 start-page: 1784 year: 2005 end-page: 1790 article-title: Cognitive control mechanisms resolve conflict through cortical amplification of task-relevant information publication-title: Nat Neurosci – volume: 48 start-page: 715 year: 2002 end-page: 722 article-title: Regularized higher-order in vivo shimming publication-title: Magn Reson Med – volume: 13 start-page: 829 833 year: 2008 end-page: 857 article-title: A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder publication-title: Mol Psychiatry – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 18 start-page: 1475 year: 2008 end-page: 1484 article-title: Dissociable neural systems resolve conflict from emotional versus nonemotional distracters publication-title: Cereb Cortex – volume: 51 start-page: 871 year: 2006 end-page: 882 article-title: Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala publication-title: Neuron – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 121 start-page: 480 year: 1992 end-page: 506 article-title: Optimizing the use of information: strategic control of activation of responses publication-title: J Exp Psychol Gen – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 108 start-page: 624 year: 2001 end-page: 652 article-title: Conflict monitoring and cognitive control publication-title: Psychol Rev – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 45 start-page: 1735 year: 2007 end-page: 1752 article-title: The contributory role of worry in emotion generation and dysregulation in generalized anxiety disorder publication-title: Behav Res Ther – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 104 start-page: 15 year: 1995 end-page: 25 article-title: Testing a tripartite model, II: exploring the symptom structure of anxiety and depression in student, adult, and patient samples publication-title: J Abnorm Psychol – volume: 43 start-page: 897 year: 2004 end-page: 905 article-title: Extinction learning in humans: role of the amygdala and vmPFC publication-title: Neuron – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 24 start-page: 539 year: 2005 end-page: 547 article-title: The neural correlates and functional integration of cognitive control in a Stroop task publication-title: Neuroimage – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 59 start-page: 829 year: 2008 end-page: 838 article-title: Neural circuitry underlying the regulation of conditioned fear and its relation to extinction publication-title: Neuron – start-page: 77 year: 2004 end-page: 108 article-title: Avoidance theory of worry and generalized anxiety disorder, in Generalized Anxiety Disorder: Advances in Research and Practice – volume: 121 start-page: 480 year: 1992 end-page: 506 article-title: Optimizing the use of information: strategic control of activation of responses publication-title: J Exp Psychol Gen – volume: 19 start-page: 1233 year: 2003 end-page: 1239 article-title: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets publication-title: Neuroimage – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 8 start-page: 539 year: 2004 end-page: 546 article-title: Conflict monitoring and anterior cingulate cortex: an update publication-title: Trends Cogn Sci – volume: 402 start-page: 179 year: 1999 end-page: 181 article-title: Conflict monitoring versus selection-for-action in anterior cingulate cortex publication-title: Nature – volume: 51 start-page: 871 year: 2006 end-page: 882 article-title: Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala publication-title: Neuron – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – volume: 18 start-page: 421 year: 2007 end-page: 428 article-title: Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli publication-title: Psychol Sci – volume: 2 start-page: 165 year: 1995 end-page: 189 article-title: Spatial registration and normalization of images publication-title: Hum Brain Mapp – volume: 9 start-page: 242 year: 2005 end-page: 249 article-title: The cognitive control of emotion publication-title: Trends Cogn Sci – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 25 start-page: 1325 year: 2005 end-page: 1335 article-title: A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data publication-title: Neuroimage – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 6 start-page: 450 year: 2003 end-page: 452 article-title: Conflict adaptation effects in the absence of executive control publication-title: Nat Neurosci – volume: 22 start-page: 360 year: 2004 end-page: 366 article-title: A method for removal of global effects from fMRI time series publication-title: Neuroimage – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 22 start-page: 360 year: 2004 end-page: 366 article-title: A method for removal of global effects from fMRI time series publication-title: Neuroimage – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – volume: 6 start-page: 218 year: 1997 end-page: 229 article-title: Psychophysiological and modulatory interactions in neuroimaging publication-title: Neuroimage – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 45 start-page: 2369 year: 2007 end-page: 2377 article-title: Amygdala activation and facial expressions: explicit emotion discrimination versus implicit emotion processing publication-title: Neuropsychologia – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 164 start-page: 1476 year: 2007 end-page: 1488 article-title: Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia publication-title: Am J Psychiatry – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 18 start-page: 421 year: 2007 end-page: 428 article-title: Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli publication-title: Psychol Sci – article-title: Disrupted amygdalar subregion functional connectivity and evidence for a compensatory network in generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 2 start-page: 189 year: 1995 end-page: 210 article-title: Statistical parametric maps in functional imaging: a general linear approach publication-title: Hum Brain Mapp – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 51 start-page: 871 year: 2006 end-page: 882 article-title: Resolving emotional conflict: a role for the rostral anterior cingulate cortex in modulating activity in the amygdala publication-title: Neuron – volume: 43 start-page: 1281 year: 2005 end-page: 1310 article-title: Preliminary evidence for an emotion dysregulation model of generalized anxiety disorder publication-title: Behav Res Ther – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 402 start-page: 179 year: 1999 end-page: 181 article-title: Conflict monitoring versus selection-for-action in anterior cingulate cortex publication-title: Nature – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 2 start-page: 189 year: 1995 end-page: 210 article-title: Statistical parametric maps in functional imaging: a general linear approach publication-title: Hum Brain Mapp – volume: 19 start-page: 152 year: 2008 end-page: 160 article-title: Affective flexibility: evaluative processing goals shape amygdala activity publication-title: Psychol Sci – volume: 18 start-page: 1475 year: 2008 end-page: 1484 article-title: Dissociable neural systems resolve conflict from emotional versus nonemotional distracters publication-title: Cereb Cortex – volume: 104 start-page: 3 year: 1995 end-page: 14 article-title: Testing a tripartite model, I: evaluating the convergent and discriminant validity of anxiety and depression symptom scales publication-title: J Abnorm Psychol – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 104 start-page: 15 year: 1995 end-page: 25 article-title: Testing a tripartite model, II: exploring the symptom structure of anxiety and depression in student, adult, and patient samples publication-title: J Abnorm Psychol – article-title: Disrupted amygdalar subregion functional connectivity and evidence for a compensatory network in generalized anxiety disorder publication-title: Arch Gen Psychiatry – start-page: 77 year: 2004 end-page: 108 article-title: Avoidance theory of worry and generalized anxiety disorder, in Generalized Anxiety Disorder: Advances in Research and Practice – volume: 39 start-page: 361 year: 1998 end-page: 368 article-title: Self-navigated spiral fMRI: interleaved versus single-shot publication-title: Magn Reson Med – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 46 start-page: 957 year: 2005 end-page: 969 article-title: Placebo in emotional processing-induced expectations of anxiety relief activate a generalized modulatory network publication-title: Neuron – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 19 start-page: 1233 year: 2003 end-page: 1239 article-title: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets publication-title: Neuroimage – volume: 210 start-page: 343 year: 2005 end-page: 352 article-title: Cytoarchitectonic mapping of the human amygdala, hippocampal region, and entorhinal cortex: intersubject variability and probability maps publication-title: Anat Embryol (Berl) – volume: 166 start-page: 302 year: 2009 end-page: 310 article-title: Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response publication-title: Am J Psychiatry – volume: 28 start-page: 11517 year: 2008 end-page: 11525 article-title: From fear to safety and back: reversal of fear in the human brain publication-title: J Neurosci – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 6 start-page: 218 year: 1997 end-page: 229 article-title: Psychophysiological and modulatory interactions in neuroimaging publication-title: Neuroimage – volume: 11 start-page: 43 year: 2000 end-page: 48 article-title: Modulating emotional responses: effects of a neocortical network on the limbic system publication-title: Neuroreport – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 48 start-page: 715 year: 2002 end-page: 722 article-title: Regularized higher-order in vivo shimming publication-title: Magn Reson Med – volume: 28 start-page: 11517 year: 2008 end-page: 11525 article-title: From fear to safety and back: reversal of fear in the human brain publication-title: J Neurosci – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – volume: 38 start-page: 284 year: 2007 end-page: 302 article-title: Delineating components of emotion and its dysregulation in anxiety and mood psychopathology publication-title: Behav Ther – volume: 43 start-page: 1281 year: 2005 end-page: 1310 article-title: Preliminary evidence for an emotion dysregulation model of generalized anxiety disorder publication-title: Behav Res Ther – volume: 19 start-page: 1233 year: 2003 end-page: 1239 article-title: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets publication-title: Neuroimage – volume: 104 start-page: 3 year: 1995 end-page: 14 article-title: Testing a tripartite model, I: evaluating the convergent and discriminant validity of anxiety and depression symptom scales publication-title: J Abnorm Psychol – volume: 4 start-page: 58 year: 1996 end-page: 73 article-title: A unified statistical approach for determining significant signals in images of cerebral activation publication-title: Hum Brain Mapp – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 6 start-page: 218 year: 1997 end-page: 229 article-title: Psychophysiological and modulatory interactions in neuroimaging publication-title: Neuroimage – volume: 8 start-page: 1784 year: 2005 end-page: 1790 article-title: Cognitive control mechanisms resolve conflict through cortical amplification of task-relevant information publication-title: Nat Neurosci – volume: 97 start-page: 1944 year: 2000 end-page: 1948 article-title: Parsing executive processes: strategic vs evaluative functions of the anterior cingulate cortex publication-title: Proc Natl Acad Sci USA – volume: 104 start-page: 15 year: 1995 end-page: 25 article-title: Testing a tripartite model, II: exploring the symptom structure of anxiety and depression in student, adult, and patient samples publication-title: J Abnorm Psychol – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 108 start-page: 624 year: 2001 end-page: 652 article-title: Conflict monitoring and cognitive control publication-title: Psychol Rev – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 63 start-page: 858 year: 2007 end-page: 863 article-title: A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder publication-title: Biol Psychiatry – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 18 start-page: 650 year: 2003 end-page: 659 article-title: Subjective rating of emotionally salient stimuli modulates neural activity publication-title: Neuroimage – volume: 8 start-page: 539 year: 2004 end-page: 546 article-title: Conflict monitoring and anterior cingulate cortex: an update publication-title: Trends Cogn Sci – volume: 40 start-page: 117 year: 2010 end-page: 124 article-title: Neural correlates of worry in generalized anxiety disorder and in normal controls: a functional MRI study publication-title: Psychol Med – volume: 303 start-page: 1023 year: 2004 end-page: 1026 article-title: Anterior cingulate conflict monitoring and adjustments in control publication-title: Science – volume: 402 start-page: 179 year: 1999 end-page: 181 article-title: Conflict monitoring versus selection-for-action in anterior cingulate cortex publication-title: Nature – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 59 start-page: 22 year: 1998 end-page: 33 article-title: The Mini-International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10 publication-title: J Clin Psychiatry – volume: 18 start-page: 650 year: 2003 end-page: 659 article-title: Subjective rating of emotionally salient stimuli modulates neural activity publication-title: Neuroimage – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 12 start-page: 232 year: 1997 end-page: 241 article-title: Reliability and validity of the MINI International Neuropsychiatric Interview (MINI): according to the SCID-P publication-title: Eur Psychiatry – volume: 64 start-page: 97 year: 2007 end-page: 106 article-title: Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 65 start-page: 568 year: 2008 end-page: 576 article-title: Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder publication-title: Arch Gen Psychiatry – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume: 165 start-page: 1193 year: 2008 end-page: 1202 article-title: Response to emotional expressions in generalized social phobia and generalized anxiety disorder: evidence for separate disorders publication-title: Am J Psychiatry – volume: 163 start-page: 1091 year: 2006 end-page: 1097 article-title: Ventrolateral prefrontal cortex activation and attentional bias in response to angry faces in adolescents with generalized anxiety disorder publication-title: Am J Psychiatry – volume-title: Pictures of Facial Affect year: 1976 ident: ajp0931r38 – ident: ajp0931r8 doi: 10.1001/archpsyc.65.5.568 – ident: ajp0931r23 doi: 10.1038/nrn2538 – ident: ajp0931r49 doi: 10.1523/JNEUROSCI.2265-08.2008 – ident: ajp0931r20 doi: 10.1126/science.1089910 – ident: ajp0931r21 doi: 10.1037/0033-295X.108.3.624 – ident: ajp0931r28 doi: 10.1016/j.neuron.2008.06.029 – ident: ajp0931r11 doi: 10.1176/appi.ajp.2008.07101682 – ident: ajp0931r40 doi: 10.1002/mrm.10267 – ident: ajp0931r47 doi: 10.1007/s00429-005-0025-5 – volume-title: American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed (DSM-IV) year: 1994 ident: ajp0931r1 – ident: ajp0931r7 doi: 10.1001/archpsyc.64.1.97 – ident: ajp0931r24 doi: 10.1038/nn1051 – ident: ajp0931r16 doi: 10.1016/j.neuron.2006.07.029 – ident: ajp0931r14 doi: 10.1176/ajp.2006.163.6.1091 – ident: ajp0931r36 doi: 10.1037/0021-843X.104.1.15 – ident: ajp0931r39 doi: 10.1002/mrm.1910390305 – ident: ajp0931r22 doi: 10.1016/j.tics.2004.10.003 – ident: ajp0931r37 doi: 10.1037/0021-843X.104.1.3 – ident: ajp0931r55 doi: 10.1097/00001756-200001170-00009 – volume-title: Manual for the State-Trait Anxiety Inventory year: 1970 ident: ajp0931r32 – volume-title: Beck Anxiety Inventory year: 1993 ident: ajp0931r34 – ident: ajp0931r18 doi: 10.1038/nn1594 – ident: ajp0931r56 doi: 10.1111/j.1467-9280.2007.01916.x – ident: ajp0931r41 doi: 10.1002/hbm.460030303 – ident: ajp0931r31 doi: 10.1016/S0924-9338(97)83297-X – ident: ajp0931r42 doi: 10.1016/j.neuroimage.2003.12.042 – ident: ajp0931r15 doi: 10.1093/cercor/bhm179 – ident: ajp0931r5 doi: 10.1016/j.beth.2006.09.001 – ident: ajp0931r13 doi: 10.1017/S0033291709005649 – volume-title: Functional neuroanatomy of anxiety: a neural circuit perspective, in Behavioral Neurobiology of Anxiety and Its Treatment ident: ajp0931r51 – ident: ajp0931r9 doi: 10.1176/appi.ajp.2008.07071060 – ident: ajp0931r33 doi: 10.1016/0005-7967(90)90135-6 – ident: ajp0931r44 doi: 10.1006/nimg.1997.0291 – volume-title: Manual for Beck Depression Inventory II (BDI-II) year: 1996 ident: ajp0931r35 – ident: ajp0931r50 doi: 10.1016/j.tics.2005.03.010 – ident: ajp0931r19 doi: 10.1037/0096-3445.121.4.480 – ident: ajp0931r27 doi: 10.1016/j.neuron.2004.08.042 – ident: ajp0931r57 doi: 10.1016/S1053-8119(02)00051-4 – ident: ajp0931r6 doi: 10.1176/appi.ajp.2007.07030504 – ident: ajp0931r48 doi: 10.1016/j.neuroimage.2004.12.034 – ident: ajp0931r3 doi: 10.1016/j.brat.2006.12.004 – ident: ajp0931r2 – ident: ajp0931r54 doi: 10.1016/j.neuropsychologia.2007.01.023 – ident: ajp0931r10 doi: 10.1016/j.biopsych.2007.08.019 – ident: ajp0931r26 doi: 10.1016/j.neuroimage.2004.09.007 – ident: ajp0931r43 doi: 10.1002/hbm.460020402 – ident: ajp0931r4 doi: 10.1016/j.brat.2004.08.008 – ident: ajp0931r12 publication-title: Arch Gen Psychiatry – ident: ajp0931r46 doi: 10.1016/S1053-8119(03)00169-1 – ident: ajp0931r52 doi: 10.1038/mp.2008.82 – volume: 59 start-page: 22 year: 1998 ident: ajp0931r30 publication-title: J Clin Psychiatry – ident: ajp0931r17 doi: 10.1038/46035 – ident: ajp0931r29 doi: 10.1016/j.neuron.2005.05.023 – ident: ajp0931r25 doi: 10.1073/pnas.97.4.1944 – ident: ajp0931r45 doi: 10.1002/(SICI)1097-0193(1996)4:1<58::AID-HBM4>3.0.CO;2-O – ident: ajp0931r53 doi: 10.1111/j.1467-9280.2008.02061.x – reference: 19996041 - Arch Gen Psychiatry. 2009 Dec;66(12):1361-72 – reference: 11488380 - Psychol Rev. 2001 Jul;108(3):624-52 – reference: 9344826 - Neuroimage. 1997 Oct;6(3):218-29 – reference: 17408704 - Neuropsychologia. 2007 Jun 11;45(10):2369-77 – reference: 18574483 - Mol Psychiatry. 2008 Sep;13(9):829, 833-57 – reference: 19419593 - Psychol Med. 2010 Jan;40(1):117-24 – reference: 16982430 - Neuron. 2006 Sep 21;51(6):871-82 – reference: 17964548 - Biol Psychiatry. 2008 May 1;63(9):858-63 – reference: 17199059 - Arch Gen Psychiatry. 2007 Jan;64(1):97-106 – reference: 17270145 - Behav Res Ther. 2007 Aug;45(8):1735-52 – reference: 18987188 - J Neurosci. 2008 Nov 5;28(45):11517-25 – reference: 7897037 - J Abnorm Psychol. 1995 Feb;104(1):15-25 – reference: 19122007 - Am J Psychiatry. 2009 Mar;166(3):302-10 – reference: 20408186 - Hum Brain Mapp. 1996;4(1):58-73 – reference: 15627596 - Neuroimage. 2005 Jan 15;24(2):539-47 – reference: 10677559 - Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1944-8 – reference: 12353290 - Magn Reson Med. 2002 Oct;48(4):715-22 – reference: 10647008 - Nature. 1999 Nov 11;402(6758):179-81 – reference: 15953423 - Neuron. 2005 Jun 16;46(6):957-69 – reference: 12880848 - Neuroimage. 2003 Jul;19(3):1233-9 – reference: 16208455 - Anat Embryol (Berl). 2005 Dec;210(5-6):343-52 – reference: 9498591 - Magn Reson Med. 1998 Mar;39(3):361-8 – reference: 18458208 - Arch Gen Psychiatry. 2008 May;65(5):568-76 – reference: 17898336 - Am J Psychiatry. 2007 Oct;164(10 ):1476-88 – reference: 16286928 - Nat Neurosci. 2005 Dec;8(12):1784-90 – reference: 2076086 - Behav Res Ther. 1990;28(6):487-95 – reference: 12667842 - Neuroimage. 2003 Mar;18(3):650-9 – reference: 12704394 - Nat Neurosci. 2003 May;6(5):450-2 – reference: 15850749 - Neuroimage. 2005 May 1;25(4):1325-35 – reference: 17576282 - Psychol Sci. 2007 May;18(5):421-8 – reference: 15110027 - Neuroimage. 2004 May;22(1):360-6 – reference: 16086981 - Behav Res Ther. 2005 Oct;43(10):1281-310 – reference: 21309113 - Curr Top Behav Neurosci. 2010;2:251-77 – reference: 14963333 - Science. 2004 Feb 13;303(5660):1023-6 – reference: 17940084 - Cereb Cortex. 2008 Jun;18(6):1475-84 – reference: 9881538 - J Clin Psychiatry. 1998;59 Suppl 20:22-33;quiz 34-57 – reference: 17697853 - Behav Ther. 2007 Sep;38(3):284-302 – reference: 15866151 - Trends Cogn Sci. 2005 May;9(5):242-9 – reference: 19153577 - Nat Rev Neurosci. 2009 Feb;10(2):141-52 – reference: 15556023 - Trends Cogn Sci. 2004 Dec;8(12):539-46 – reference: 10683827 - Neuroreport. 2000 Jan 17;11(1):43-8 – reference: 18786365 - Neuron. 2008 Sep 11;59(5):829-38 – reference: 15363399 - Neuron. 2004 Sep 16;43(6):897-905 – reference: 1431740 - J Exp Psychol Gen. 1992 Dec;121(4):480-506 – reference: 7897050 - J Abnorm Psychol. 1995 Feb;104(1):3-14 – reference: 20439393 - Am J Psychiatry. 2010 May;167(5):489-92 – reference: 18271863 - Psychol Sci. 2008 Feb;19(2):152-60 – reference: 18483136 - Am J Psychiatry. 2008 Sep;165(9):1193-202 – reference: 16741211 - Am J Psychiatry. 2006 Jun;163(6):1091-7 |
| SSID | ssj0000372 |
| Score | 2.5130239 |
| Snippet | ObjectiveClinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder,... Clinical data suggest that abnormalities in the regulation of emotional processing contribute to the pathophysiology of generalized anxiety disorder, yet these... |
| SourceID | pubmedcentral proquest pubmed pascalfrancis crossref appi |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 545 |
| SubjectTerms | Adaptation, Psychological - physiology Adult Adult and adolescent clinical studies Amygdala - physiopathology Anxiety Anxiety Disorders - physiopathology Anxiety disorders. Neuroses Biological and medical sciences Case-Control Studies Conflict (Psychology) Emotions - physiology Female Gyrus Cinguli - physiopathology Humans Magnetic Resonance Imaging Male Medical sciences Miscellaneous Neural Pathways - physiopathology Neurosciences Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology Psychopathology. Psychiatry Studies |
| Title | Failure of Anterior Cingulate Activation and Connectivity With the Amygdala During Implicit Regulation of Emotional Processing in Generalized Anxiety Disorder |
| URI | http://dx.doi.org/10.1176/appi.ajp.2009.09070931 https://www.ncbi.nlm.nih.gov/pubmed/20123913 https://www.proquest.com/docview/220492676 https://www.proquest.com/docview/733525570 https://pubmed.ncbi.nlm.nih.gov/PMC4367202 |
| Volume | 167 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3bbtNAEF1FRUJICHHHFKp94C2YJnbstR-jNlFC1BYhF_pmOet1a2jtqEkk6MfwdXwIM3vxpY0U4MWK7Ox6kzmei3fmDCHv3EGYCLAktsfDxB6IgNsBn7t2EOAmExqdDAuFj479yeng45l31un8bmQtrVfzD_xmY13J_0gVzoFcsUr2HyRbTQon4DPIF44gYTj-lYzHSY5Z5dKbxD8oL6-7B2CLsCWX6A65aV0mdwhkSgvXzSK-ytevsqrk53maXCbdQ1WvOJUZ5jnmKp_rzl4y-VB1-wF56soCXQqjWavzG_Bbh8UPmQBqCD2bfm9UF7AUTbaKdrK1dO2j2VSlHlzldW3252GkUjZmpmKxLqGYnIzGkXTC11f597KC0Oj4RE70JS_KtPl2Q23MNzNFzMo-meXk_A5wa9UeerK5cK3aVasPjWGvoag9RWKpbb6niKzvmhMmeZQXWFb4zbCbhqAlQ226Wvzdt-xqle3oOBDCeAwchXv4CftsHE5ntb_gMscEafgDdB073Ht_853Be8ALLU_q4SJZwkOdqW4sm8Kl21m_DTcqekwe6fiHDhWYn5COKJ6S-0c6w-MZ-aUxTcuMGkzTCtO0xjQFTNMmpilimgI6qME0VZimBtO0xjROX2Ga1pimeUEbmKYa09Rg-jk5HY-ig4mte4jYCYQCK9txhe_0ucgET-Z87iN1Aniw3GNuGAQZC3vhgIG2gjgGlBUYpCyDmMkPeRCkfQcs1AuyU5SFeEVogCW1bsaSlIHbmyaByPwAd-LTPs88ISzyHsUS64doGcv4mvmxPAtSxJavYWykaBHPiC_mmo8f28Jcbh23X41bKEaarSP2WuiohhlgWmTXwKVeveP0kEyU-Rah1VWwPbihmBSiXC9jhgWbyOFnkZcKW_XUGKuFfdcirIW66gtIa9--UuQXkt5-4PrM6Tmvt616lzyoNcYbsrO6Xou3ECGs5nvyAfsDOhEYGQ |
| linkProvider | Flying Publisher |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Failure+of+Anterior+Cingulate+Activation+and+Connectivity+With+the+Amygdala+During+Implicit+Regulation+of+Emotional+Processing+in+Generalized+Anxiety+Disorder&rft.jtitle=The+American+journal+of+psychiatry&rft.au=ETKIN%2C+Amit&rft.au=PRATER%2C+Katherine+E&rft.au=HOEFT%2C+Fumiko&rft.au=MENON%2C+Vinod&rft.date=2010-05-01&rft.pub=American+Psychiatric+Association&rft.issn=0002-953X&rft.volume=167&rft.issue=5&rft.spage=545&rft.epage=554&rft_id=info:doi/10.1176%2Fappi.ajp.2009.09070931&rft.externalDBID=n%2Fa&rft.externalDocID=22772572 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0002-953X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0002-953X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0002-953X&client=summon |