Parvoviruses: Small Does Not Mean Simple

• Published in: Annual review of virology Vol. 1; no. 1; p. 517
• Main Authors: Cotmore, Susan F, Tattersall, Peter
• Format: Journal Article
• Language: English
• Published: United States 29.09.2014
• Subjects: dynamic protein cylinder; viral diversity; capsid portals; early virion release; limited coding capacity; rolling hairpin replication

Parvoviruses are small, rugged, nonenveloped protein particles containing a linear, nonpermuted, single-stranded DNA genome of ∼5 kb. Their limited coding potential requires optimal adaptation to the environment of particular host cells, where entry is mediated by a variable program of capsid dynami...