Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study - Umhau, John C; Momenan, Reza; Schwandt, Melanie L; Singley, Erick; Lifshitz, Mariel; Doty, Linda; Adams, Lauren J; Vengeliene, Valentina; Spanagel, Rainer; Zhang, Yan; Shen, Jun; George, David T; et al. (Archives of general psychiatry, 2010)
Keywords: Acamprosate; Adult; Alcohol Deterrents - adverse effects; Alcohol Deterrents - therapeutic use; Alcoholism - physiopathology; Alcoholism - rehabilitation; Corticotropin-Releasing Hormone - physiology; Creatine - metabolism; Dexamethasone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glucocorticoids; Glutamic Acid - metabolism; Gyrus Cinguli - drug effects; Gyrus Cinguli - physiopathology; Humans; Magnetic Resonance Spectroscopy; Male; Taurine - adverse effects; Taurine - analogs & derivatives; Taurine - therapeutic use