Efficacy of Tecovirimat (ST-246) in Nonhuman Primates Infected with Variola Virus (Smallpox)

• Published in: Antimicrobial Agents and Chemotherapy Vol. 57; no. 12; pp. 6246 - 6253
• Main Authors: MUCKER, Eric M, GOFF, Arthur J, CLEMMONS, Cody J, HUDSON, Paul, HRUBY, Dennis E, SHAMBLIN, Joshua D, GROSENBACH, Douglas W, DAMON, Inger K, MEHAL, Jason M, HOLMAN, Robert C, CARROLL, Darin, GALLARDO, Nadia, OLSON, Victoria A
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.12.2013
• Subjects: Animal models; Animals; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral Agents; Antiviral Agents - administration & dosage; Antiviral Agents - therapeutic use; Benzamides; Benzamides - administration & dosage; Benzamides - therapeutic use; Biological and medical sciences; Isoindoles; Isoindoles - administration & dosage; Isoindoles - therapeutic use; Macaca; Male; Medical sciences; Orthopoxvirus; Pharmacology. Drug treatments; Poxviridae Infections; Poxviridae Infections - blood; Poxviridae Infections - drug therapy; Random Allocation; Treatment Outcome; Variola virus; Variola virus - drug effects; Variola virus - pathogenicity; Virus; Infection; Chordopoxvirinae; Variola virus; Poxviridae; Orthopoxvirus; Treatment efficiency; Nonhuman primate; Tecovirimat; Benzamide derivatives; Antiviral

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