Vancomycin-Rifampin Combination Therapy Has Enhanced Efficacy against an Experimental Staphylococcus aureus Prosthetic Joint Infection

• Published in: Antimicrobial Agents and Chemotherapy Vol. 57; no. 10; pp. 5080 - 5086
• Main Authors: Niska, Jared A., Shahbazian, Jonathan H., Ramos, Romela Irene, Francis, Kevin P., Bernthal, Nicholas M., Miller, Lloyd S.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.10.2013
• Subjects: Animals; Anti-Bacterial Agents; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial diseases; Biological and medical sciences; Diseases of the osteoarticular system; Drug Therapy, Combination; Experimental Therapeutics; Human bacterial diseases; Infectious diseases; Male; Medical sciences; Mice; Mice, Inbred C57BL; Miscellaneous. Osteoarticular involvement in other diseases; Pharmacology. Drug treatments; Prosthesis-Related Infections; Prosthesis-Related Infections - drug therapy; Rifampin; Rifampin - administration & dosage; Rifampin - therapeutic use; Staphylococcal Infections; Staphylococcal Infections - drug therapy; Staphylococcal infections, streptococcal infections, pneumococcal infections; Staphylococcus aureus; Staphylococcus aureus - drug effects; Staphylococcus aureus - pathogenicity; Vancomycin; Vancomycin - administration & dosage; Vancomycin - therapeutic use; Drug combination; Peptides; Prosthesis; Treatment efficiency; Diseases of the osteoarticular system; Arthritis; Vancomycin; Infection; Antibiotic; Rifampicin; Glycopeptide; Polypeptide; Bacteriosis; Bacteria; Micrococcales; Micrococcaceae; Antituberculous agent; Combined treatment; Protein synthesis inhibitor; Antibacterial agent; Staphylococcal infection; Staphylococcus aureus

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