Randomized Pilot Trial of Eight Weeks of Bedaquiline (TMC207) Treatment for Multidrug-Resistant Tuberculosis: Long-Term Outcome, Tolerability, and Effect on Emergence of Drug Resistance

• Published in: Antimicrobial Agents and Chemotherapy Vol. 56; no. 6; pp. 3271 - 3276
• Main Authors: Diacon, A. H., Donald, P. R., Pym, A., Grobusch, M., Patientia, R. F., Mahanyele, R., Bantubani, N., Narasimooloo, R., De Marez, T., van Heeswijk, R., Lounis, N., Meyvisch, P., Andries, K., McNeeley, D. F.
• Format: Journal Article
• Language: English
• Published: Washington, DC American Society for Microbiology 01.06.2012
• Subjects: Acne; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antitubercular Agents; Antitubercular Agents - therapeutic use; Bacterial diseases; Biological and medical sciences; Chest; Clarithromycin - therapeutic use; Clinical Therapeutics; Clinical trials; Cycloserine - therapeutic use; Dapsone - therapeutic use; Diarylquinolines; Drug resistance; Erythromycin - therapeutic use; ethambutol; Ethionamide; Female; Hearing; Human bacterial diseases; Humans; Infectious diseases; Isoxazoles - therapeutic use; Lung; Male; Medical sciences; Mycobacterium; Nausea; Ofloxacin; Ofloxacin - therapeutic use; Oxazolidinones - therapeutic use; Pain; Pharmacokinetics; Pharmacology. Drug treatments; Quinolines - therapeutic use; Sputum; Tuberculosis; Tuberculosis and atypical mycobacterial infections; Tuberculosis, Multidrug-Resistant; Tuberculosis, Multidrug-Resistant - drug therapy; Treatment resistance; Prognosis; Toxicity; Mycobacterial infection; Epidemiology; Long term; Infection; Randomization; Treatment; Tuberculosis; Multiple resistance; Bacteriosis; Clinical trial

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