Radiosynthesis, Preclinical, and Clinical Positron Emission Tomography Studies of Carbon-11 Labeled Endogenous and Natural Exogenous Compounds

• Published in: Chemical reviews Vol. 123; no. 1; pp. 105 - 229
• Main Authors: Shegani, Antonio, Kealey, Steven, Luzi, Federico, Basagni, Filippo, Machado, Joana do Mar, Ekici, Sevban Doğan, Ferocino, Alessandra, Gee, Antony D., Bongarzone, Salvatore
• Format: Journal Article
• Language: English
• Published: United States American Chemical Society 11.01.2023
• Subjects: Alcohols; automation; Carbon; Carbon Radioisotopes - chemistry; Emission analysis; Humans; Peptides; Positron emission; Positron-Emission Tomography; Radiochemistry; Radioisotopes; radiolabeling; Radiolabelling; Radiopharmaceuticals; Review; scanners; Tomography; Vitamins

The presence of positron emission tomography (PET) centers at most major hospitals worldwide, along with the improvement of PET scanner sensitivity and the introduction of total body PET systems, has increased the interest in the PET tracer development using the short-lived radionuclides carbon-11....